Adolescent Stress—Induced Epigenetic Control of Dopaminergic Neurons via Glucocorticoids
Niwa, Minae, Jaaro-Peled, Hanna, Tankou, Stephanie, Seshadri, Saurav, Hikida, Takatoshi, Matsumoto, Yurie, Cascella, Nicola G., Kano, Shin-ichi, Ozaki, Norio, Nabeshima, Toshitaka, Sawa, Akira
Published in Science (American Association for the Advancement of Science) (18.01.2013)
Published in Science (American Association for the Advancement of Science) (18.01.2013)
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Journal Article
Neurodevelopmental mechanisms of schizophrenia: understanding disturbed postnatal brain maturation through neuregulin-1–ErbB4 and DISC1
Jaaro-Peled, Hanna, Hayashi-Takagi, Akiko, Seshadri, Saurav, Kamiya, Atsushi, Brandon, Nicholas J, Sawa, Akira
Published in Trends in neurosciences (Regular ed.) (01.09.2009)
Published in Trends in neurosciences (Regular ed.) (01.09.2009)
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Journal Article
Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1
Penzes, Peter, Houslay, Miles D, Brandon, Nicholas J, Murdoch, Hannah, Hayashi-Takagi, Akiko, Dunlop, Allan J, Graziane, Nick, Sawa, Akira, Makino, Yuichi, Yan, Zhen, Ishizuka, Koko, Takaki, Manabu, Xie, Zhong, Srivastava, Deepak P, Kamiya, Atsushi, Seshadri, Anupamaa J, Seshadri, Saurav, Baraban, Jay M, Tomoda, Toshifumi
Published in Nature neuroscience (01.03.2010)
Published in Nature neuroscience (01.03.2010)
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Journal Article
Knockdown of DISC1 by In Utero Gene Transfer Disturbs Postnatal Dopaminergic Maturation in the Frontal Cortex and Leads to Adult Behavioral Deficits
Niwa, Minae, Kamiya, Atsushi, Murai, Rina, Kubo, Ken-ichiro, Gruber, Aaron J., Tomita, Kenji, Lu, Lingling, Tomisato, Shuta, Jaaro-Peled, Hanna, Seshadri, Saurav, Hiyama, Hideki, Huang, Beverly, Kohda, Kazuhisa, Noda, Yukihiro, O'Donnell, Patricio, Nakajima, Kazunori, Sawa, Akira, Nabeshima, Toshitaka
Published in Neuron (Cambridge, Mass.) (25.02.2010)
Published in Neuron (Cambridge, Mass.) (25.02.2010)
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Dominant-negative DISC1 transgenic mice display schizophrenia-associated phenotypes detected by measures translatable to humans
Hikida, Takatoshi, Jaaro-Peled, Hanna, Seshadri, Saurav, Oishi, Kenichi, Hookway, Caroline, Kong, Stephanie, Wu, Di, Xue, Rong, Andradé, Manuella, Tankou, Stephanie, Mori, Susumu, Gallagher, Michela, Ishizuka, Koko, Pletnikov, Mikhail, Kida, Satoshi, Sawa, Akira
Published in Proceedings of the National Academy of Sciences - PNAS (04.09.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (04.09.2007)
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Journal Article
Calcium Imaging in Drug Discovery for Psychiatric Disorders
Seshadri, Saurav, Hoeppner, Daniel J., Tajinda, Katsunori
Published in Frontiers in psychiatry (23.07.2020)
Published in Frontiers in psychiatry (23.07.2020)
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Journal Article
Neuronal Avalanches in Input and Associative Layers of Auditory Cortex
Bowen, Zac, Winkowski, Daniel E, Seshadri, Saurav, Plenz, Dietmar, Kanold, Patrick O
Published in Frontiers in systems neuroscience (04.09.2019)
Published in Frontiers in systems neuroscience (04.09.2019)
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Journal Article
Disrupted-in-Schizophrenia-1 expression is regulated by β-site amyloid precursor protein cleaving enzyme-1-neuregulin cascade
Seshadri, Saurav, Kamiya, Atsushi, Yokota, Yukako, Prikulis, Ingrid, Kano, Shin-ichi, Hayashi-Takagi, Akiko, Stanco, Amelia, Eom, Tae-Yeon, Rao, Sarada, Ishizuka, Koko, Wong, Philip, Korth, Carsten, Anton, E.S, Sawa, Akira
Published in Proceedings of the National Academy of Sciences - PNAS (23.03.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (23.03.2010)
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Journal Article
Impaired NMDA receptor transmission alters striatal synapses and DISC1 protein in an age-dependent manner
Ramsey, Amy J, Milenkovic, Marija, Oliveira, Ana F, Escobedo-Lozoya, Yasmin, Seshadri, Saurav, Salahpour, Ali, Sawa, Akira, Yasuda, Ryohei, Caron, Marc G
Published in Proceedings of the National Academy of Sciences - PNAS (05.04.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (05.04.2011)
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Journal Article
Migration defects by DISC1 knockdown in C57BL/6, 129X1/SvJ, and ICR strains via in utero gene transfer and virus-mediated RNAi
Kubo, Ken-ichiro, Tomita, Kenji, Uto, Asuka, Kuroda, Keisuke, Seshadri, Saurav, Cohen, Jared, Kaibuchi, Kozo, Kamiya, Atsushi, Nakajima, Kazunori
Published in Biochemical and biophysical research communications (01.10.2010)
Published in Biochemical and biophysical research communications (01.10.2010)
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Journal Article
Interneuronal DISC1 regulates NRG1-ErbB4 signalling and excitatory–inhibitory synapse formation in the mature cortex
Seshadri, Saurav, Faust, Travis, Ishizuka, Koko, Delevich, Kristen, Chung, Youjin, Kim, Sun-Hong, Cowles, Martis, Niwa, Minae, Jaaro-Peled, Hanna, Tomoda, Toshifumi, Lai, Cary, Anton, E. S., Li, Bo, Sawa, Akira
Published in Nature communications (11.12.2015)
Published in Nature communications (11.12.2015)
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Journal Article
DISC1-dependent switch from progenitor proliferation to migration in the developing cortex
Ishizuka, Koko, Kamiya, Atsushi, Oh, Edwin C., Kanki, Hiroaki, Seshadri, Saurav, Robinson, Jon F., Murdoch, Hannah, Dunlop, Allan J., Kubo, Ken-ichiro, Furukori, Keiko, Huang, Beverly, Zeledon, Mariela, Hayashi-Takagi, Akiko, Okano, Hideyuki, Nakajima, Kazunori, Houslay, Miles D., Katsanis, Nicholas, Sawa, Akira
Published in Nature (London) (05.05.2011)
Published in Nature (London) (05.05.2011)
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Journal Article
DISC1 regulates trafficking and processing of APP and Aβ generation
Shahani, N, Seshadri, S, Jaaro-Peled, H, Ishizuka, K, Hirota-Tsuyada, Y, Wang, Q, Koga, M, Sedlak, T W, Korth, C, Brandon, N J, Kamiya, A, Subramaniam, S, Tomoda, T, Sawa, A
Published in Molecular psychiatry (01.07.2015)
Published in Molecular psychiatry (01.07.2015)
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Journal Article
Clinical utility of neuronal cells directly converted from fibroblasts of patients for neuropsychiatric disorders: studies of lysosomal storage diseases and channelopathy
Kano, S, Yuan, M, Cardarelli, R A, Maegawa, G, Higurashi, N, Gaval-Cruz, M, Wilson, A M, Tristan, C, Kondo, M A, Chen, Y, Koga, M, Obie, C, Ishizuka, K, Seshadri, S, Srivastava, R, Kato, T A, Horiuchi, Y, Sedlak, T W, Lee, Y, Rapoport, J L, Hirose, S, Okano, H, Valle, D, O'Donnell, P, Sawa, A, Kai, M
Published in Current molecular medicine (01.01.2015)
Published in Current molecular medicine (01.01.2015)
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Journal Article
Neorodevelopmental mechanisms of schizophrenia: understanding disturbed postnatal brain muturation through neuregulin-1-ErbB4 and DISC1
Jaaro-Peled, Hanna, Hayashi-Takagi, Akiko, Seshadri, Saurav, Kamiya, Atsushi, Brandon, Nicholas J, Sawa, Akira
Published in Trends in neurosciences (Regular ed.) (01.09.2009)
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Published in Trends in neurosciences (Regular ed.) (01.09.2009)
Journal Article
Disrupted-in-Schizophrenia-1 expression is regulated by [beta]-site amyloid precursor protein cleaving enzyme-1-neuregulin cascade
Seshadri, Saurav, Kamiya, Atsushi, Yokota, Yukako, Prikulis, Ingrid, Kano, Shin-ichi, Hayashi-Takagi, Akiko, Stanco, Amelia, Eom, Tae-Yeon, Rao, Sarada, Ishizuka, Koko, Wong, Philip, Korth, Carsten, Anton, E S, Sawa, Akira
Published in Proceedings of the National Academy of Sciences - PNAS (23.03.2010)
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Published in Proceedings of the National Academy of Sciences - PNAS (23.03.2010)
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