HCV genotype 1-6 NS3 residue 80 substitutions impact protease inhibitor activity and promote viral escape
Pham, Long V., Jensen, Sanne Brun, Fahnøe, Ulrik, Pedersen, Martin Schou, Tang, Qi, Ghanem, Lubna, Ramirez, Santseharay, Humes, Daryl, Serre, Stéphanie B.N., Schønning, Kristian, Bukh, Jens, Gottwein, Judith M.
Published in Journal of hepatology (01.03.2019)
Published in Journal of hepatology (01.03.2019)
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Hypervariable Region 1 Differentially Impacts Viability of Hepatitis C Virus Strains of Genotypes 1 to 6 and Impairs Virus Neutralization
PRENTOE, Jannick, JENSEN, Tanja B, MEULEMAN, Philip, SERRE, Stéphanie B. N, SCHEEL, Troels K. H, LEROUX-ROELS, Geert, GOTTWEIN, Judith M, BUKH, Jens
Published in Journal of Virology (01.03.2011)
Published in Journal of Virology (01.03.2011)
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Substitutions at NS3 Residue 155, 156, or 168 of Hepatitis C Virus Genotypes 2 to 6 Induce Complex Patterns of Protease Inhibitor Resistance
Jensen, Sanne B, Serre, Stéphanie B N, Humes, Daryl G, Ramirez, Santseharay, Li, Yi-Ping, Bukh, Jens, Gottwein, Judith M
Published in Antimicrobial agents and chemotherapy (01.12.2015)
Published in Antimicrobial agents and chemotherapy (01.12.2015)
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Hepatitis C Virus Genotype 1 to 6 Protease Inhibitor Escape Variants: In Vitro Selection, Fitness, and Resistance Patterns in the Context of the Infectious Viral Life Cycle
Serre, Stéphanie B N, Jensen, Sanne B, Ghanem, Lubna, Humes, Daryl G, Ramirez, Santseharay, Li, Yi-Ping, Krarup, Henrik, Bukh, Jens, Gottwein, Judith M
Published in Antimicrobial agents and chemotherapy (01.06.2016)
Published in Antimicrobial agents and chemotherapy (01.06.2016)
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Hypervariable Region 1 Deletion and Required Adaptive Envelope Mutations Confer Decreased Dependency on Scavenger Receptor Class B Type I and Low-Density Lipoprotein Receptor for Hepatitis C Virus
Prentoe, Jannick, Serre, Stéphanie B N, Ramirez, Santseharay, Nicosia, Alfredo, Gottwein, Judith M, Bukh, Jens
Published in Journal of Virology (01.02.2014)
Published in Journal of Virology (01.02.2014)
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Identification of Alpha Interferon-Induced Envelope Mutations of Hepatitis C Virus In Vitro Associated with Increased Viral Fitness and Interferon Resistance
Serre, Stéphanie B N, Krarup, Henrik B, Bukh, Jens, Gottwein, Judith M
Published in Journal of Virology (01.12.2013)
Published in Journal of Virology (01.12.2013)
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Combination Treatment with Hepatitis C Virus Protease and NS5A Inhibitors Is Effective against Recombinant Genotype 1a, 2a, and 3a Viruses
GOTTWEIN, Judith M, JENSEN, Sanne B, LI, Yi-Ping, GHANEM, Lubna, SCHEEL, Troels K. H, SERRE, Stéphanie B. N, MIKKELSEN, Lotte, BUKH, Jens
Published in Antimicrobial Agents and Chemotherapy (01.03.2013)
Published in Antimicrobial Agents and Chemotherapy (01.03.2013)
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Adapted J6/JFH1-Based Hepatitis C Virus Recombinants with Genotype-Specific NS4A Show Similar Efficacies against Lead Protease Inhibitors, Alpha Interferon, and a Putative NS4A Inhibitor
GOTTWEIN, Judith M, JENSEN, Sanne B, SERRE, Stéphanie B. N, GHANEM, Lubna, SCHEEL, Troels K. H, JENSEN, Tanja B, KRARUP, Henrik, UZCATEGUI, Nathalie, MIKKELSEN, Lotte S, BUKH, Jens
Published in Antimicrobial Agents and Chemotherapy (01.12.2013)
Published in Antimicrobial Agents and Chemotherapy (01.12.2013)
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Development and Application of Hepatitis C Reporter Viruses with Genotype 1 to 7 Core-Nonstructural Protein 2 (NS2) Expressing Fluorescent Proteins or Luciferase in Modified JFH1 NS5A
GOTTWEIN, Judith M, JENSEN, Tanja B, MATHIESEN, Christian K, MEULEMAN, Philip, SERRE, Stephanie B. N, LADEMANN, Jacob B, GHANEM, Lubna, SCHEEL, Troels K. H, LEROUX-ROELS, Geert, BUKH, Jens
Published in Journal of Virology (01.09.2011)
Published in Journal of Virology (01.09.2011)
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