MYC and MET cooperatively drive hepatocellular carcinoma with distinct molecular traits and vulnerabilities
Sequera, Celia, Grattarola, Margherita, Holczbauer, Agnes, Dono, Rosanna, Pizzimenti, Stefania, Barrera, Giuseppina, Wangensteen, Kirk J, Maina, Flavio
Published in Cell death & disease (24.11.2022)
Published in Cell death & disease (24.11.2022)
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Journal Article
C3G downregulation induces the acquisition of a mesenchymal phenotype that enhances aggressiveness of glioblastoma cells
Manzano, Sara, Gutierrez-Uzquiza, Alvaro, Bragado, Paloma, Sequera, Celia, Herranz, Óscar, Rodrigo-Faus, María, Jauregui, Patricia, Morgner, Stephanie, Rubio, Ignacio, Guerrero, Carmen, Porras, Almudena
Published in Cell death & disease (06.04.2021)
Published in Cell death & disease (06.04.2021)
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Journal Article
How Rap and its GEFs control liver physiology and cancer development. C3G alterations in human hepatocarcinoma
Sequera, Celia, Manzano, Sara, Guerrero, Carmen, Porras, Almudena
Published in Hepatic oncology (01.01.2018)
Published in Hepatic oncology (01.01.2018)
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Journal Article
C3G Is Upregulated in Hepatocarcinoma, Contributing to Tumor Growth and Progression and to HGF/MET Pathway Activation
Sequera, Celia, Bragado, Paloma, Manzano, Sara, Arechederra, Maria, Richelme, Sylvie, Gutiérrez-Uzquiza, Alvaro, Sánchez, Aránzazu, Maina, Flavio, Guerrero, Carmen, Porras, Almudena
Published in Cancers (01.08.2020)
Published in Cancers (01.08.2020)
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Journal Article
MYC and MET cooperatively drive hepatocellular carcinoma with distinct molecular traits and vulnerabilities
Sequera, Célia, Grattarola, Margherita, Holczbauer, Agnes, Dono, Rosanna, Pizzimenti, Stefania, Barrera, Giuseppina, Wangensteen, Kirk, Maina, Flavio
Published in Cell death & disease (24.11.2022)
Published in Cell death & disease (24.11.2022)
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Journal Article
Enhanced Wild-Type MET Receptor Levels in Mouse Hepatocytes Attenuates Insulin-Mediated Signaling
Rada, Patricia, Lamballe, Fabienne, Carceller-López, Elena, Hitos, Ana B, Sequera, Celia, Maina, Flavio, Valverde, Ángela M
Published in Cells (Basel, Switzerland) (24.02.2022)
Published in Cells (Basel, Switzerland) (24.02.2022)
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Journal Article
p38 MAPK Down-regulates Fibulin 3 Expression through Methylation of Gene Regulatory Sequences
Arechederra, María, Priego, Neibla, Vázquez-Carballo, Ana, Sequera, Celia, Gutiérrez-Uzquiza, Álvaro, Cerezo-Guisado, María Isabel, Ortiz-Rivero, Sara, Roncero, Cesáreo, Cuenda, Ana, Guerrero, Carmen, Porras, Almudena
Published in The Journal of biological chemistry (13.02.2015)
Published in The Journal of biological chemistry (13.02.2015)
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Journal Article
ADAMTSL5 is an epigenetically activated gene underlying tumorigenesis and drug resistance in hepatocellular carcinoma
Arechederra, Maria, Bazai, Sehrish K., Abdouni, Ahmed, Sequera, Celia, Mead, Timothy J., Richelme, Sylvie, Daian, Fabrice, Audebert, Stéphane, Dono, Rosanna, Lozano, Anthony, Gregoire, Damien, Hibner, Urszula, Allende, Daniela S., Apte, Suneel S., Maina, Flavio
Published in Journal of hepatology (01.04.2021)
Published in Journal of hepatology (01.04.2021)
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Journal Article
Abstract 1974: C3G down-regulation in glioblastoma induces a pro-invasive and glycolytic phenotype, accompanied by RTKs dysregulation
Manzano, Sara, Herranz, Óscar, Bragado, Paloma, Jáuregui, Patricia, Rodrigo, María, Sequera, Celia, Baquero, Cristina, Palao, Nerea, Rubio, Ignacio, Gutierrez-Uzquiza, Álvaro, Guerrero, Carmen, Porras, Almudena
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
C3G down-regulation enhances pro-migratory and stemness properties of oval cells by promoting an epithelial-mesenchymal-like process
Palao, Nerea, Sequera, Celia, Cuesta, Ángel M, Baquero, Cristina, Bragado, Paloma, Gutierrez-Uzquiza, Alvaro, Sánchez, Aránzazu, Guerrero, Carmen, Porras, Almudena
Published in International journal of biological sciences (01.01.2022)
Published in International journal of biological sciences (01.01.2022)
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Journal Article
p38 MAPK down-regulates fibulin 3 expression through methylation of gene regulatory sequences: role in migration and invasion
Arechederra, María, Priego, Neibla, Vázquez-Carballo, Ana, Sequera, Celia, Gutiérrez-Uzquiza, Álvaro, Cerezo-Guisado, María Isabel, Ortiz-Rivero, Sara, Roncero, Cesáreo, Cuenda, Ana, Guerrero, Carmen, Porras, Almudena
Published in The Journal of biological chemistry (13.02.2015)
Published in The Journal of biological chemistry (13.02.2015)
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Journal Article
C3G promotes a selective release of angiogenic factors from activated mouse platelets to regulate angiogenesis and tumor metastasis
Martín-Granado, Víctor, Ortiz-Rivero, Sara, Carmona, Rita, Gutiérrez-Herrero, Sara, Barrera, Mario, San-Segundo, Laura, Sequera, Celia, Perdiguero, Pedro, Lozano, Francisco, Martín-Herrero, Francisco, González-Porras, José Ramón, Muñoz-Chápuli, Ramón, Porras, Almudena, Guerrero, Carmen
Published in Oncotarget (19.12.2017)
Published in Oncotarget (19.12.2017)
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Journal Article
TWEAK promotes migration and invasion in MEFs through a mechanism dependent on ERKs activation and Fibulin 3 down‐regulation
Sequera, Celia, Vázquez‐Carballo, Ana, Arechederra, María, Fernández‐Veledo, Sonia, Porras, Almudena
Published in Journal of cellular physiology (01.02.2018)
Published in Journal of cellular physiology (01.02.2018)
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Journal Article
C3G knock-down enhances migration and invasion by increasing Rap1-mediated p38α activation, while it impairs tumor growth through p38α-independent mechanisms
Priego, Neibla, Arechederra, María, Sequera, Celia, Bragado, Paloma, Vázquez-Carballo, Ana, Gutiérrez-Uzquiza, Álvaro, Martín-Granado, Víctor, Ventura, Juan José, Kazanietz, Marcelo G, Guerrero, Carmen, Porras, Almudena
Published in Oncotarget (19.07.2016)
Published in Oncotarget (19.07.2016)
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Journal Article