Genomic analysis identifies new drivers and progression pathways in skin basal cell carcinoma
Bonilla, Ximena, Parmentier, Laurent, King, Bryan, Bezrukov, Fedor, Kaya, Gürkan, Zoete, Vincent, Seplyarskiy, Vladimir B, Sharpe, Hayley J, McKee, Thomas, Letourneau, Audrey, Ribaux, Pascale G, Popadin, Konstantin, Basset-Seguin, Nicole, Chaabene, Rouaa Ben, Santoni, Federico A, Andrianova, Maria A, Guipponi, Michel, Garieri, Marco, Verdan, Carole, Grosdemange, Kerstin, Sumara, Olga, Eilers, Martin, Aifantis, Iannis, Michielin, Olivier, de Sauvage, Frederic J, Antonarakis, Stylianos E, Nikolaev, Sergey I
Published in Nature genetics (01.04.2016)
Published in Nature genetics (01.04.2016)
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Journal Article
APOBEC-induced mutations in human cancers are strongly enriched on the lagging DNA strand during replication
Seplyarskiy, Vladimir B, Soldatov, Ruslan A, Popadin, Konstantin Y, Antonarakis, Stylianos E, Bazykin, Georgii A, Nikolaev, Sergey I
Published in Genome research (01.02.2016)
Published in Genome research (01.02.2016)
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Journal Article
Extraordinary Genetic Diversity in a Wood Decay Mushroom
Baranova, Maria A, Logacheva, Maria D, Penin, Aleksey A, Seplyarskiy, Vladimir B, Safonova, Yana Y, Naumenko, Sergey A, Klepikova, Anna V, Gerasimov, Evgeny S, Bazykin, Georgii A, James, Timothy Y, Kondrashov, Alexey S
Published in Molecular biology and evolution (01.10.2015)
Published in Molecular biology and evolution (01.10.2015)
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Journal Article
Gene Age Predicts the Strength of Purifying Selection Acting on Gene Expression Variation in Humans
Popadin, Konstantin Y., Gutierrez-Arcelus, Maria, Lappalainen, Tuuli, Buil, Alfonso, Steinberg, Julia, Nikolaev, Sergey I., Lukowski, Samuel W., Bazykin, Georgii A., Seplyarskiy, Vladimir B., Ioannidis, Panagiotis, Zdobnov, Evgeny M., Dermitzakis, Emmanouil T., Antonarakis, Stylianos E.
Published in American journal of human genetics (04.12.2014)
Published in American journal of human genetics (04.12.2014)
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Journal Article
Germline de novo mutation clusters arise during oocyte aging in genomic regions with high double-strand-break incidence
Goldmann, Jakob M., Seplyarskiy, Vladimir B., Wong, Wendy S. W., Vilboux, Thierry, Neerincx, Pieter B., Bodian, Dale L., Solomon, Benjamin D., Veltman, Joris A., Deeken, John F., Gilissen, Christian, Niederhuber, John E.
Published in Nature genetics (01.04.2018)
Published in Nature genetics (01.04.2018)
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Journal Article
APOBEC3A/B-induced mutagenesis is responsible for 20% of heritable mutations in the TpCpW context
Seplyarskiy, Vladimir B, Andrianova, Maria A, Bazykin, Georgii A
Published in Genome research (01.02.2017)
Published in Genome research (01.02.2017)
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Journal Article
Evolution of Local Mutation Rate and Its Determinants
Terekhanova, Nadezhda V, Seplyarskiy, Vladimir B, Soldatov, Ruslan A, Bazykin, Georgii A
Published in Molecular biology and evolution (01.05.2017)
Published in Molecular biology and evolution (01.05.2017)
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Journal Article
Discovery of recessive effect of human polymerase δ proofreading deficiency through mutational analysis of POLD1-mutated normal and cancer cells
Andrianova, Maria A, Seplyarskiy, Vladimir B, Terradas, Mariona, Sánchez-Heras, Ana Beatriz, Mur, Pilar, Soto, José Luis, Aiza, Gemma, Borràs, Emma, Kondrashov, Fyodor A, Kondrashov, Alexey S, Bazykin, Georgii A, Valle, Laura
Published in European journal of human genetics : EJHG (01.07.2024)
Published in European journal of human genetics : EJHG (01.07.2024)
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Journal Article
Population sequencing data reveal a compendium of mutational processes in the human germ line
Seplyarskiy, Vladimir B, Soldatov, Ruslan A, Koch, Evan, McGinty, Ryan J, Goldmann, Jakob M, Hernandez, Ryan D, Barnes, Kathleen, Correa, Adolfo, Burchard, Esteban G, Ellinor, Patrick T, McGarvey, Stephen T, Mitchell, Braxton D, Vasan, Ramachandran S, Redline, Susan, Silverman, Edwin, Weiss, Scott T, Arnett, Donna K, Blangero, John, Boerwinkle, Eric, He, Jiang, Montgomery, Courtney, Rao, D C, Rotter, Jerome I, Taylor, Kent D, Brody, Jennifer A, Chen, Yii-Der Ida, de Las Fuentes, Lisa, Hwu, Chii-Min, Rich, Stephen S, Manichaikul, Ani W, Mychaleckyj, Josyf C, Palmer, Nicholette D, Smith, Jennifer A, Kardia, Sharon L R, Peyser, Patricia A, Bielak, Lawrence F, O'Connor, Timothy D, Emery, Leslie S, Gilissen, Christian, Wong, Wendy S W, Kharchenko, Peter V, Sunyaev, Shamil
Published in Science (American Association for the Advancement of Science) (27.08.2021)
Published in Science (American Association for the Advancement of Science) (27.08.2021)
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Publisher Correction: Germline de novo mutation clusters arise during oocyte aging in genomic regions with high double-strand-break incidence
Goldmann, Jakob M., Seplyarskiy, Vladimir B., Wong, Wendy S. W., Vilboux, Thierry, Neerincx, Pieter B., Bodian, Dale L., Solomon, Benjamin D., Veltman, Joris A., Deeken, John F., Gilissen, Christian, Niederhuber, John E.
Published in Nature genetics (01.08.2021)
Published in Nature genetics (01.08.2021)
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Journal Article
Germline PMS2 and somatic POLE exonuclease mutations cause hypermutability of the leading DNA strand in biallelic mismatch repair deficiency syndrome brain tumours
Andrianova, Maria A, Chetan, Ghati Kasturirangan, Sibin, Madathan Kandi, Mckee, Thomas, Merkler, Doron, Narasinga, Rao KVL, Ribaux, Pascale, Blouin, Jean‐Louis, Makrythanasis, Periklis, Seplyarskiy, Vladimir B, Antonarakis, Stylianos E, Nikolaev, Sergey I
Published in The Journal of pathology (01.11.2017)
Published in The Journal of pathology (01.11.2017)
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Journal Article
Crossing-over in a hypervariable species preferentially occurs in regions of high local similarity
Seplyarskiy, Vladimir B, Logacheva, Maria D, Penin, Aleksey A, Baranova, Maria A, Leushkin, Evgeny V, Demidenko, Natalia V, Klepikova, Anna V, Kondrashov, Fyodor A, Kondrashov, Alexey S, James, Timothy Y
Published in Molecular biology and evolution (01.11.2014)
Published in Molecular biology and evolution (01.11.2014)
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Journal Article
Error-prone bypass of DNA lesions during lagging-strand replication is a common source of germline and cancer mutations
Seplyarskiy, Vladimir B., Akkuratov, Evgeny E., Akkuratova, Natalia, Andrianova, Maria A., Nikolaev, Sergey I., Bazykin, Georgii A., Adameyko, Igor, Sunyaev, Shamil R.
Published in Nature genetics (01.01.2019)
Published in Nature genetics (01.01.2019)
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