Rapid and direct control of target protein levels with VHL-recruiting dTAG molecules
Nabet, Behnam, Ferguson, Fleur M., Seong, Bo Kyung A., Kuljanin, Miljan, Leggett, Alan L., Mohardt, Mikaela L., Robichaud, Amanda, Conway, Amy S., Buckley, Dennis L., Mancias, Joseph D., Bradner, James E., Stegmaier, Kimberly, Gray, Nathanael S.
Published in Nature communications (18.09.2020)
Published in Nature communications (18.09.2020)
Get full text
Journal Article
A Metastatic Mouse Model Identifies Genes That Regulate Neuroblastoma Metastasis
Seong, Bo Kyung A, Fathers, Kelly E, Hallett, Robin, Yung, Christina K, Stein, Lincoln D, Mouaaz, Samar, Kee, Lynn, Hawkins, Cynthia E, Irwin, Meredith S, Kaplan, David R
Published in Cancer research (Chicago, Ill.) (01.02.2017)
Published in Cancer research (Chicago, Ill.) (01.02.2017)
Get full text
Journal Article
An In Vivo CRISPR Screening Platform for Prioritizing Therapeutic Targets in AML
Lin, Shan, Larrue, Clément, Scheidegger, Nastassja K, Seong, Bo Kyung A, Dharia, Neekesh V, Kuljanin, Miljan, Wechsler, Caroline S, Kugener, Guillaume, Robichaud, Amanda L, Conway, Amy Saur, Mashaka, Thelma, Mouche, Sarah, Adane, Biniam, Ryan, Jeremy A, Mancias, Joseph D, Younger, Scott T, Piccioni, Federica, Lee, Lynn H, Wunderlich, Mark, Letai, Anthony, Tamburini, Jérôme, Stegmaier, Kimberly
Published in Cancer discovery (01.02.2022)
Published in Cancer discovery (01.02.2022)
Get full text
Journal Article
TRIM8 modulates the EWS/FLI oncoprotein to promote survival in Ewing sarcoma
Seong, Bo Kyung A., Dharia, Neekesh V., Lin, Shan, Donovan, Katherine A., Chong, Shasha, Robichaud, Amanda, Conway, Amy, Hamze, Amanda, Ross, Linda, Alexe, Gabriela, Adane, Biniam, Nabet, Behnam, Ferguson, Fleur M., Stolte, Björn, Wang, Emily Jue, Sun, Jialin, Darzacq, Xavier, Piccioni, Federica, Gray, Nathanael S., Fischer, Eric S., Stegmaier, Kimberly
Published in Cancer cell (13.09.2021)
Published in Cancer cell (13.09.2021)
Get full text
Journal Article
STAG2 loss rewires oncogenic and developmental programs to promote metastasis in Ewing sarcoma
Adane, Biniam, Alexe, Gabriela, Seong, Bo Kyung A., Lu, Diana, Hwang, Elizabeth E., Hnisz, Denes, Lareau, Caleb A., Ross, Linda, Lin, Shan, Dela Cruz, Filemon S., Richardson, Melissa, Weintraub, Abraham S., Wang, Sarah, Iniguez, Amanda Balboni, Dharia, Neekesh V., Conway, Amy Saur, Robichaud, Amanda L., Tanenbaum, Benjamin, Krill-Burger, John M., Vazquez, Francisca, Schenone, Monica, Berman, Jason N., Kung, Andrew L., Carr, Steven A., Aryee, Martin J., Young, Richard A., Crompton, Brian D., Stegmaier, Kimberly
Published in Cancer cell (14.06.2021)
Published in Cancer cell (14.06.2021)
Get full text
Journal Article
The ETS transcription factor ETV6 constrains the transcriptional activity of EWS–FLI to promote Ewing sarcoma
Lu, Diana Y., Ellegast, Jana M., Ross, Kenneth N., Malone, Clare F., Lin, Shan, Mabe, Nathaniel W., Dharia, Neekesh V., Meyer, Ashleigh, Conway, Amy, Su, Angela H., Selich-Anderson, Julia, Taslim, Cenny, Byrum, Andrea K., Seong, Bo Kyung A., Adane, Biniam, Gray, Nathanael S., Rivera, Miguel N., Lessnick, Stephen L., Stegmaier, Kimberly
Published in Nature cell biology (01.02.2023)
Published in Nature cell biology (01.02.2023)
Get full text
Journal Article
Gene Fusions Create Partner and Collateral Dependencies Essential to Cancer Cell Survival
Gillani, Riaz, Seong, Bo Kyung A, Crowdis, Jett, Conway, Jake R, Dharia, Neekesh V, Alimohamed, Saif, Haas, Brian J, Han, Kyuho, Park, Jihye, Dietlein, Felix, He, Meng Xiao, Imamovic, Alma, Ma, Clement, Bassik, Michael C, Boehm, Jesse S, Vazquez, Francisca, Gusev, Alexander, Liu, David, Janeway, Katherine A, McFarland, James M, Stegmaier, Kimberly, Van Allen, Eliezer M
Published in Cancer research (Chicago, Ill.) (01.08.2021)
Published in Cancer research (Chicago, Ill.) (01.08.2021)
Get full text
Journal Article
Structure-activity relationship study of THZ531 derivatives enables the discovery of BSJ-01-175 as a dual CDK12/13 covalent inhibitor with efficacy in Ewing sarcoma
Jiang, Baishan, Jiang, Jie, Kaltheuner, Ines H., Iniguez, Amanda Balboni, Anand, Kanchan, Ferguson, Fleur M., Ficarro, Scott B., Seong, Bo Kyung Alex, Greifenberg, Ann Katrin, Dust, Sofia, Kwiatkowski, Nicholas P., Marto, Jarrod A., Stegmaier, Kimberly, Zhang, Tinghu, Geyer, Matthias, Gray, Nathanael S.
Published in European journal of medicinal chemistry (05.10.2021)
Published in European journal of medicinal chemistry (05.10.2021)
Get full text
Journal Article
Vitamin D Receptor Activation Attenuates Hippo Pathway Effectors and Cell Survival in Metastatic Neuroblastoma
Ladumor, Yagnesh, Seong, Bo Kyung Alex, Hallett, Robin, Valencia-Sama, Ivette, Adderley, Teresa, Wang, Yingying, Kee, Lynn, Gont, Alexander, Kaplan, David R, Irwin, Meredith S
Published in Molecular cancer research (03.06.2022)
Published in Molecular cancer research (03.06.2022)
Get full text
Journal Article
Abstract 3106: Targeting vitamin D signalling in metastatic neuroblastoma
Ladumor, Yagnesh, Seong, Bo Kyung Alex, Hallett, Robin, Adderley, Teresa, Wang, Yingying, Kee, Lynn, Kaplan, David, Irwin, Meredith
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Get full text
Journal Article
Abstract B50: Targeting EWS/FLI fusion oncoprotein stability/degradation in Ewing sarcoma
Seong, Bo Kyung Alex, Lin, Shan, Donovan, Katherine, Robichaud, Amanda, Stolte, Bjorn, Wang, Emily, Dharia, Neekesh, Nabet, Behnam, Piccioni, Federica, Gray, Nathanael, Fischer, Eric, Stegmaier, Kimberly
Published in Cancer research (Chicago, Ill.) (15.07.2020)
Published in Cancer research (Chicago, Ill.) (15.07.2020)
Get full text
Journal Article
An In Vivo CRISPR Screening Platform to Identify New Therapeutic Targets in AML
Lin, Shan, Larrue, Clement, Scheidegger, Nastassja K., Seong, Bo Kyung A., Dharia, Neekesh V, Wechsler, Caroline, Kugener, Guillaume, Robinchaud, Amanda L, Conway, Amy, Adane, Biniam, Younger, Scott, Piccioni, Federica, Lee, Lynn, Wunderlich, Mark, Tamburini, Jerome, Stegmaier, Kimberly
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
Get full text
Journal Article
SLC5A3 Transports Myo-Inositol to Support the Growth of Acute Myeloid Leukemia
Lin, Shan, Scheidegger, Nastassja K., Alexe, Gabriela, Seong, Bo Kyung A., Dharia, Neekesh V, Wechsler, Caroline, Kugener, Guillaume, Robinchaud, Amanda L, Conway, Amy, Adane, Biniam, Younger, Scott, Piccioni, Federica, Lee, Lynn, Wunderlich, Mark, Stegmaier, Kimberly
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
Get full text
Journal Article
Abstract 3244: EWS-FLI1-driven upregulation of UGT3A2 unlocks drug sensitivity pathway in Ewing sarcoma
Olaoye, Olasunkanmi, Harrington, Colleen, Ross, Kenneth, Seong, Bo Kyung A., de Waal, Luk, Qi, Jun, Roth, Jennifer, Stegmaier, Kimberly
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Get full text
Journal Article
Abstract 96: Gene fusions create partner and collateral dependencies that are essential to cancer cell survival
Gillani, Riaz, Seong, Bo Kyung A., Crowdis, Jett, Conway, Jake R., Dharia, Neekesh V., Alimohamed, Saif, Haas, Brian J., Han, Kyuho, Park, Jihye, Liu, David, Dietlein, Felix, He, Meng Xiao, Imamovic, Alma, Ma, Clement, Bassik, Michael C., Boehm, Jesse S., Vazquez, Francisca, Gusev, Alexander, Janeway, Katherine A., McFarland, James M., Stegmaier, Kimberly, Van Allen, Eliezer M.
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Get full text
Journal Article
The absence of a novel intron 19-retaining ALK transcript ( ALK -I19) and MYCN amplification correlates with an excellent clinical outcome in neuroblastoma patients
Alshareef, Abdulraheem, Irwin, Meredith S, Gupta, Nidhi, Zhang, Hai-Feng, Haque, Moinul, Findlay, Scott D, Seong, Bo Kyung Alex, Lai, Justine, Rayis, Mohammed, Al-Dandan, Sadeq, Lai, Raymond
Published in Oncotarget (13.02.2018)
Published in Oncotarget (13.02.2018)
Get full text
Journal Article
A Personality Specialized Artificial Emotion for a Scrolling Shooter game
Jun-Seok Ham, Myung-Bum Jung, Bo-Kyung Seong, Jun-Hyoung Park, Min-ho Park, Il-Ju Ko
Published in 2008 10th International Conference on Advanced Communication Technology (01.02.2008)
Published in 2008 10th International Conference on Advanced Communication Technology (01.02.2008)
Get full text
Conference Proceeding