NLRX1 ligand, docosahexaenoic acid, ameliorates LPS-induced inflammatory hyperalgesia by decreasing TRAF6/IKK/IκB-α/NF-κB signaling pathway activity
Dilsah Ezgi Yilmaz, Sefika Pinar Senol, Meryem Temiz-Resitoglu, Seyhan Sahan-Firat, Bahar Tunctan
Published in Cellular and Molecular Biology (08.10.2023)
Published in Cellular and Molecular Biology (08.10.2023)
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Journal Article
Pro-inflammatory GPR75 and anti-apoptotic phospholipase signaling pathways contribute to the ameliorating effect of soluble epoxide hydrolase inhibition on chronic experimental autoimmune encephalomyelitis in mice
Horat, Mehmet Furkan, Senol, Sefika Pinar, Bahceli, Omer, Temiz-Resitoglu, Meryem, Sahan-Firat, Seyhan, Sevim, Serhan, Tunctan, Bahar
Published in Cellular and Molecular Biology (31.10.2023)
Published in Cellular and Molecular Biology (31.10.2023)
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Journal Article
Suppression of TLR4/MyD88/TAK1/NF-κB/COX-2 Signaling Pathway in the Central Nervous System by Bexarotene, a Selective RXR Agonist, Prevents Hyperalgesia in the Lipopolysaccharide-Induced Pain Mouse Model
Senol, Sefika Pinar, Temiz-Resitoglu, Meryem, Guden, Demet Sinem, Sari, Ayse Nihal, Sahan-Firat, Seyhan, Tunctan, Bahar
Published in Neurochemical research (01.03.2021)
Published in Neurochemical research (01.03.2021)
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Journal Article
Soluble epoxide hydrolase inhibitor trifluoromethoxyphenyl‐3‐(1‐propionylpiperidin‐4‐yl)urea prevents hyperalgesia through regulating NLRC4 inflammasome‐related pro‐inflammatory and anti‐inflammatory signaling pathways in the lipopolysaccharide‐induced pain mouse model
Cagli, Ali, Senol, Sefika Pinar, Temiz‐Resitoglu, Meryem, Guden, Demet Sinem, Sari, Ayse Nihal, Sahan‐Firat, Seyhan, Tunctan, Bahar
Published in Drug development research (01.09.2021)
Published in Drug development research (01.09.2021)
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Journal Article
Eicosanoids derived from cytochrome P450 pathway of arachidonic acid and inflammatory shock
Tunctan, Bahar, Senol, Sefika Pinar, Temiz-Resitoglu, Meryem, Guden, Demet Sinem, Sahan-Firat, Seyhan, Falck, John R., Malik, Kafait U.
Published in Prostaglandins & other lipid mediators (01.12.2019)
Published in Prostaglandins & other lipid mediators (01.12.2019)
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Journal Article
mTOR inhibition as a possible pharmacological target in the management of systemic inflammatory response and associated neuroinflammation by lipopolysaccharide challenge in rats
Guden, Demet Sinem, Temiz-Resitoglu, Meryem, Senol, Sefika Pinar, Kibar, Deniz, Yilmaz, Sakir Necat, Tunctan, Bahar, Malik, Kafait U, Sahan-Firat, Seyhan
Published in Canadian journal of physiology and pharmacology (01.09.2021)
Published in Canadian journal of physiology and pharmacology (01.09.2021)
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Journal Article
NF‐κB activation mediates LPS‐or zymosan‐induced hypotension and inflammation reversed by BAY61‐3606, a selective Syk inhibitor, in rat models of septic and non‐septic shock
Sahan‐Firat, Seyhan, Temiz‐Resitoglu, Meryem, Guden, Demet Sinem, Senol, Sefika Pinar, Sari, Ayse Nihal, Cil, Meltem, Unsal, Demet, Korkmaz, Belma, Tunctan, Bahar, Malik, Kafait U., Buharalioglu, Cuneyt Kemal
Published in Clinical and experimental pharmacology & physiology (01.02.2019)
Published in Clinical and experimental pharmacology & physiology (01.02.2019)
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Journal Article
Pyroptosis and necroptosis inhibitor necrosulfonamide ameliorates lipopolysaccharide-induced inflammatory hyperalgesia in mice
Ozgen, Beyza, Senol, Sefika Pinar, Yilmaz, Dilsah Ezgi, Temiz-Resitoglu, Meryem, Bahceli, Omer, Tunctan, Bahar
Published in Farmacija (16.11.2023)
Published in Farmacija (16.11.2023)
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Journal Article
Inhibition of NLRP3 Inflammasome Prevents LPS-Induced Inflammatory Hyperalgesia in Mice: Contribution of NF-κB, Caspase-1/11, ASC, NOX, and NOS Isoforms
Dolunay, Abdurrahman, Senol, Sefika Pinar, Temiz-Resitoglu, Meryem, Guden, Demet Sinem, Sari, Ayse Nihal, Sahan-Firat, Seyhan, Tunctan, Bahar
Published in Inflammation (01.04.2017)
Published in Inflammation (01.04.2017)
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Journal Article
Inhibition of mTOR protects against skeletal muscle and kidney injury following hindlimb ischemia-reperfusion in rats by regulating MEK1/ERK1/2 activity
AKINCI UYSAL, Çağla, TEMİZ REŞİTOĞLU, Meryem, GÜDEN, Demet Sinem, ŞENOL, Sefika Pınar, VEZİR, Özden, SUCU, Nehir, TUNÇTAN, Bahar, MALİK, Kafait U., FIRAT, Seyhan
Published in Cukurova Medical Journal (01.01.2022)
Published in Cukurova Medical Journal (01.01.2022)
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Journal Article
Pharmacological inhibition of soluble epoxide hydrolase attenuates chronic experimental autoimmune encephalomyelitis by modulating inflammatory and anti-inflammatory pathways in an inflammasome-dependent and -independent manner
Biliktu, Merve, Senol, Sefika Pinar, Temiz-Resitoglu, Meryem, Guden, Demet Sinem, Horat, Mehmet Furkan, Sahan-Firat, Seyhan, Sevim, Serhan, Tunctan, Bahar
Published in Inflammopharmacology (01.12.2020)
Published in Inflammopharmacology (01.12.2020)
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Journal Article
Activation of GPR75 Signaling Pathway Contributes to the Effect of a 20-HETE Mimetic, 5,14-HEDGE, to Prevent Hypotensive and Tachycardic Responses to Lipopolysaccharide in a Rat Model of Septic Shock
Tunctan, Bahar, Senol, Sefika Pinar, Temiz-Resitoglu, Meryem, Yilmaz, Dilsah Ezgi, Guden, Demet Sinem, Bahceli, Omer, Horat, Mehmet Furkan, Sahan-Firat, Seyhan, Sari, Ayse Nihal, Falck, John R, Anugu, Raghunath Reddy, Malik, Kafait U
Published in Journal of cardiovascular pharmacology (01.08.2022)
Published in Journal of cardiovascular pharmacology (01.08.2022)
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Journal Article
NLRX1 ligand, docosahexaenoic acid, ameliorates LPS-induced inflammatory hyperalgesia by decreasing TRAF6/IKK/IkB-a/NF-kB signaling pathway activity
Yilmaz, Dilsah Ezgi, Senol, Sefika Pinar, Temiz-Resitoglu, Meryem, Sahan-Firat, Seyhan, Tunctan, Bahar
Published in Cellular and molecular biology (Noisy-le-Grand, France) (30.09.2023)
Published in Cellular and molecular biology (Noisy-le-Grand, France) (30.09.2023)
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Journal Article
Bexarotene Ameliorates LPS-Induced Hyperalgesia: Contribution of TLR4/MyD88-Dependent Pro-Inflammatory, Anti-Apoptotic and Anti-Inflammatory Signaling Pathways
Bahceli, Omer, Pinar Seno, Sefika, Temiz-Resi, Meryem, Furkan Hor, Mehmet, Sahan-Fira, Seyhan, Tunctan, Bahar
Published in International journal of pharmacology (15.06.2022)
Published in International journal of pharmacology (15.06.2022)
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Journal Article
NF ‐κB activation mediates LPS ‐or zymosan‐induced hypotension and inflammation reversed by BAY 61‐3606, a selective Syk inhibitor, in rat models of septic and non‐septic shock
Sahan‐Firat, Seyhan, Temiz‐Resitoglu, Meryem, Guden, Demet Sinem, Senol, Sefika Pinar, Sari, Ayse Nihal, Cil, Meltem, Unsal, Demet, Korkmaz, Belma, Tunctan, Bahar, Malik, Kafait U., Buharalioglu, Cuneyt Kemal
Published in Clinical and experimental pharmacology & physiology (01.02.2019)
Published in Clinical and experimental pharmacology & physiology (01.02.2019)
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Journal Article
Contribution of PPARα/β/γ, AP-1, importin-α3, and RXRα to the protective effect of 5,14-HEDGE, a 20-HETE mimetic, against hypotension, tachycardia, and inflammation in a rat model of septic shock
Senol, Sefika Pinar, Temiz, Meryem, Guden, Demet Sinem, Cecen, Pelin, Sari, Ayse Nihal, Sahan-Firat, Seyhan, Falck, John R., Dakarapu, Rambabu, Malik, Kafait U., Tunctan, Bahar
Published in Inflammation research (01.05.2016)
Published in Inflammation research (01.05.2016)
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Journal Article
Contribution of PPAR alpha / beta / gamma , AP-1, importin- alpha 3, and RXR alpha to the protective effect of 5,14-HEDGE, a 20-HETE mimetic, against hypotension, tachycardia, and inflammation in a rat model of septic shock
Senol, Sefika Pinar, Temiz, Meryem, Guden, Demet Sinem, Cecen, Pelin, Sari, Ayse Nihal, Sahan-Firat, Seyhan, Falck, John R, Dakarapu, Rambabu, Malik, Kafait U, Tunctan, Bahar
Published in Inflammation research (01.05.2016)
Published in Inflammation research (01.05.2016)
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Journal Article
Inhibition of NLRP3 Inflammasome Prevents LPS-Induced Inflammatory Hyperalgesia in Mice: Contribution of NF-[kappa]B, Caspase-1/11, ASC, NOX, and NOS Isoforms
Dolunay, Abdurrahman, Senol, Sefika Pinar, Temiz-resitoglu, Meryem, Guden, Demet Sinem, Sari, Ayse Nihal, Sahan-firat, Seyhan, Tunctan, Bahar
Published in Inflammation (01.04.2017)
Published in Inflammation (01.04.2017)
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Journal Article
Contribution of PPAR[alpha]/[beta]/[gamma], AP-1, importin-[alpha]3, and RXR[alpha] to the protective effect of 5,14-HEDGE, a 20-HETE mimetic, against hypotension, tachycardia, and inflammation in a rat model of septic shock
Senol, Sefika Pinar, Temiz, Meryem, Guden, Demet Sinem, Cecen, Pelin, Sari, Ayse Nihal, Sahan-firat, Seyhan, Falck, John R, Dakarapu, Rambabu, Malik, Kafait U, Tunctan, Bahar
Published in Inflammation research (01.05.2016)
Published in Inflammation research (01.05.2016)
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Journal Article
The role of peroxisome proliferator-activated receptors in the pathogenesis of insulin resistance and septic shock
Senol, Sefika, Tunctan, Bahar
Published in Marmara Üniversitesi Saglik Bilimleri Enstitüsü Dergisi (01.01.2015)
Published in Marmara Üniversitesi Saglik Bilimleri Enstitüsü Dergisi (01.01.2015)
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Book Review