Global Proteomic Assessment of the Classical Protein-Tyrosine Phosphatome and “Redoxome”
Karisch, Robert, Fernandez, Minerva, Taylor, Paul, Virtanen, Carl, St-Germain, Jonathan R., Jin, Lily L., Harris, Isaac S., Mori, Jun, Mak, Tak W., Senis, Yotis A., Östman, Arne, Moran, Michael F., Neel, Benjamin G.
Published in Cell (02.09.2011)
Published in Cell (02.09.2011)
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Journal Article
Collagen type I degradation fragments act through the collagen receptor LAIR-1 to provide a negative feedback for osteoclast formation
Boraschi-Diaz, Iris, Mort, John S., Brömme, Dieter, Senis, Yotis A., Mazharian, Alexandra, Komarova, Svetlana V.
Published in Bone (New York, N.Y.) (01.12.2018)
Published in Bone (New York, N.Y.) (01.12.2018)
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Journal Article
Megakaryocyte-specific deletion of the protein-tyrosine phosphatases Shp1 and Shp2 causes abnormal megakaryocyte development, platelet production, and function
Mazharian, Alexandra, Mori, Jun, Wang, Ying-Jie, Heising, Silke, Neel, Benjamin G., Watson, Steve P., Senis, Yotis A.
Published in Blood (16.05.2013)
Published in Blood (16.05.2013)
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Journal Article
Megakaryocyte NLRP3 hyperactivation induces mild anemia and potentiates inflammatory response in mice
Bourne, Joshua H, Campos, Joana, Hopkin, Sophie J, Whitworth, Katharine, Palis, James, Senis, Yotis A, Rayes, Julie, Iqbal, Asif J, Brill, Alexander
Published in Frontiers in immunology (09.08.2023)
Published in Frontiers in immunology (09.08.2023)
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Journal Article
Mice Lacking the Inhibitory Collagen Receptor LAIR-1 Exhibit a Mild Thrombocytosis and Hyperactive Platelets
Smith, Christopher W, Thomas, Steven G, Raslan, Zaher, Patel, Pushpa, Byrne, Maxwell, Lordkipanidzé, Marie, Bem, Danai, Meyaard, Linde, Senis, Yotis A, Watson, Steve P, Mazharian, Alexandra
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2017)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2017)
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Journal Article
Evaluation of the Total Thrombus-Formation System (T-TAS): application to human and mouse blood analysis
Al Ghaithi, Rashid, Mori, Jun, Nagy, Zoltan, Maclachlan, Annabel, Hardy, Lewis, Philippou, Helen, Hethershaw, Emma, Morgan, Neil V., Senis, Yotis A., Harrison, Paul
Published in Platelets (Edinburgh) (03.10.2019)
Published in Platelets (Edinburgh) (03.10.2019)
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Journal Article
Heparan sulfates are critical regulators of the inhibitory megakaryocyte-platelet receptor G6b-B
Vögtle, Timo, Sharma, Sumana, Mori, Jun, Nagy, Zoltan, Semeniak, Daniela, Scandola, Cyril, Geer, Mitchell J, Smith, Christopher W, Lane, Jordan, Pollack, Scott, Lassila, Riitta, Jouppila, Annukka, Barr, Alastair J, Ogg, Derek J, Howard, Tina D, McMiken, Helen J, Warwicker, Juli, Geh, Catherine, Rowlinson, Rachel, Abbott, W Mark, Eckly, Anita, Schulze, Harald, Wright, Gavin J, Mazharian, Alexandra, Fütterer, Klaus, Rajesh, Sundaresan, Douglas, Michael R, Senis, Yotis A
Published in eLife (22.08.2019)
Published in eLife (22.08.2019)
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Journal Article
Lymphatic blood filling in CLEC-2-deficient mouse models
Haining, Elizabeth J, Lowe, Kate L, Wichaiyo, Surasak, Kataru, Raghu P, Nagy, Zoltan, Kavanagh, Dean Pj, Lax, Sian, Di, Ying, Nieswandt, Bernhard, Ho-Tin-Noé, Benoît, Mehrara, Babak J, Senis, Yotis A, Rayes, Julie, Watson, Steve P
Published in Platelets (Edinburgh) (03.04.2021)
Published in Platelets (Edinburgh) (03.04.2021)
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Journal Article
Platelet Src family kinases: A tale of reversible phosphorylation
Senis, Yotis A., Nagy, Zoltan, Mori, Jun, Lane, Sophia, Lane, Patrick
Published in Research and practice in thrombosis and haemostasis (01.03.2021)
Published in Research and practice in thrombosis and haemostasis (01.03.2021)
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Journal Article
The tyrosine phosphatase CD148 is an essential positive regulator of platelet activation and thrombosis
Senis, Yotis A., Tomlinson, Michael G., Ellison, Stuart, Mazharian, Alexandra, Lim, Jenson, Zhao, Yan, Kornerup, Kristin N., Auger, Jocelyn M., Thomas, Steve G., Dhanjal, Tarvinder, Kalia, Neena, Zhu, Jing W., Weiss, Arthur, Watson, Steve P.
Published in Blood (14.05.2009)
Published in Blood (14.05.2009)
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Journal Article
Mice lacking the ITIM-containing receptor G6b-B exhibit macrothrombocytopenia and aberrant platelet function
Mazharian, Alexandra, Wang, Ying-Jie, Mori, Jun, Bem, Danai, Finney, Brenda, Heising, Silke, Gissen, Paul, White, James G, Berndt, Michael C, Gardiner, Elizabeth E, Nieswandt, Bernhard, Douglas, Michael R, Campbell, Robert D, Watson, Steve P, Senis, Yotis A
Published in Science signaling (30.10.2012)
Published in Science signaling (30.10.2012)
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Journal Article
LAIR-1 and PECAM-1 function via the same signaling pathway to inhibit GPVI-mediated platelet activation
Smith, Christopher W., Nagy, Zoltan, Geer, Mitchell J., Pike, Jeremy A., Patel, Pushpa, Senis, Yotis A., Mazharian, Alexandra
Published in Research and practice in thrombosis and haemostasis (01.08.2024)
Published in Research and practice in thrombosis and haemostasis (01.08.2024)
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Journal Article
TREM-like transcript 1: a more sensitive marker of platelet activation than P-selectin in humans and mice
Smith, Christopher W., Raslan, Zaher, Parfitt, Lola, Khan, Abdullah O., Patel, Pushpa, Senis, Yotis A., Mazharian, Alexandra
Published in Blood advances (28.08.2018)
Published in Blood advances (28.08.2018)
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Journal Article
Enhanced BCR signaling inflicts early plasmablast and germinal center B cell death
Yam-Puc, Juan Carlos, Zhang, Lingling, Maqueda-Alfaro, Raul A, Garcia-Ibanez, Laura, Zhang, Yang, Davies, Jessica, Senis, Yotis A, Snaith, Michael, Toellner, Kai-Michael
Published in iScience (19.02.2021)
Published in iScience (19.02.2021)
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Journal Article
Identification of Tspan9 as a novel platelet tetraspanin and the collagen receptor GPVI as a component of tetraspanin microdomains
Protty, Majd B, Watkins, Nicholas A, Colombo, Dario, Thomas, Steven G, Heath, Victoria L, Herbert, John M J, Bicknell, Roy, Senis, Yotis A, Ashman, Leonie K, Berditchevski, Fedor, Ouwehand, Willem H, Watson, Steve P, Tomlinson, Michael G
Published in Biochemical journal (01.01.2009)
Published in Biochemical journal (01.01.2009)
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Journal Article
A Comprehensive Proteomics and Genomics Analysis Reveals Novel Transmembrane Proteins in Human Platelets and Mouse Megakaryocytes Including G6b-B, a Novel Immunoreceptor Tyrosine-based Inhibitory Motif Protein
Senis, Yotis A., Tomlinson, Michael G., García, Ángel, Dumon, Stephanie, Heath, Victoria L., Herbert, John, Cobbold, Stephen P., Spalton, Jennifer C., Ayman, Sinem, Antrobus, Robin, Zitzmann, Nicole, Bicknell, Roy, Frampton, Jon, Authi, Kalwant S., Martin, Ashley, Wakelam, Michael J.O., Watson, Stephen P.
Published in Molecular & cellular proteomics (01.03.2007)
Published in Molecular & cellular proteomics (01.03.2007)
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Journal Article
G6b-B Inhibits Constitutive and Agonist-induced Signaling by Glycoprotein VI and CLEC-2
Mori, Jun, Pearce, Andrew C., Spalton, Jennifer C., Grygielska, Beata, Eble, Johannes A., Tomlinson, Michael G., Senis, Yotis A., Watson, Steve P.
Published in The Journal of biological chemistry (19.12.2008)
Published in The Journal of biological chemistry (19.12.2008)
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