Defective Mitophagy in XPA via PARP-1 Hyperactivation and NAD+/SIRT1 Reduction
Fang, Evandro Fei, Scheibye-Knudsen, Morten, Brace, Lear E., Kassahun, Henok, SenGupta, Tanima, Nilsen, Hilde, Mitchell, James R., Croteau, Deborah L., Bohr, Vilhelm A.
Published in Cell (08.05.2014)
Published in Cell (08.05.2014)
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Journal Article
NAD+ augmentation restores mitophagy and limits accelerated aging in Werner syndrome
Fang, Evandro F., Hou, Yujun, Lautrup, Sofie, Jensen, Martin Borch, Yang, Beimeng, SenGupta, Tanima, Caponio, Domenica, Khezri, Rojyar, Demarest, Tyler G., Aman, Yahyah, Figueroa, David, Morevati, Marya, Lee, Ho-Joon, Kato, Hisaya, Kassahun, Henok, Lee, Jong-Hyuk, Filippelli, Deborah, Okur, Mustafa Nazir, Mangerich, Aswin, Croteau, Deborah L., Maezawa, Yoshiro, Lyssiotis, Costas A., Tao, Jun, Yokote, Koutaro, Rusten, Tor Erik, Mattson, Mark P., Jasper, Heinrich, Nilsen, Hilde, Bohr, Vilhelm A.
Published in Nature communications (21.11.2019)
Published in Nature communications (21.11.2019)
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Journal Article
Assessment of dopaminergic neuron degeneration in a C. elegans model of Parkinson’s disease
Palikaras, Konstantinos, SenGupta, Tanima, Nilsen, Hilde, Tavernarakis, Nektarios
Published in STAR protocols (17.06.2022)
Published in STAR protocols (17.06.2022)
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Journal Article
Crosstalk between Different DNA Repair Pathways Contributes to Neurodegenerative Diseases
Gupta, Swapnil, You, Panpan, SenGupta, Tanima, Nilsen, Hilde, Sharma, Kulbhushan
Published in Biology (Basel, Switzerland) (19.02.2021)
Published in Biology (Basel, Switzerland) (19.02.2021)
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Journal Article
Uracil Accumulation and Mutagenesis Dominated by Cytosine Deamination in CpG Dinucleotides in Mice Lacking UNG and SMUG1
Alsøe, Lene, Sarno, Antonio, Carracedo, Sergio, Domanska, Diana, Dingler, Felix, Lirussi, Lisa, SenGupta, Tanima, Tekin, Nuriye Basdag, Jobert, Laure, Alexandrov, Ludmil B., Galashevskaya, Anastasia, Rada, Cristina, Sandve, Geir Kjetil, Rognes, Torbjørn, Krokan, Hans E., Nilsen, Hilde
Published in Scientific reports (03.08.2017)
Published in Scientific reports (03.08.2017)
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Journal Article
Correction: Publisher Correction: Base excision repair AP endonucleases and mismatch repair act together to induce checkpoint-mediated autophagy
SenGupta, Tanima, Torgersen, Maria Lyngaas, Kassahun, Henok, Vellai, Tibor, Simonsen, Anne, Nilsen, Hilde
Published in Nature communications (29.03.2018)
Published in Nature communications (29.03.2018)
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Journal Article
Targeted Central Nervous System Irradiation with Proton Microbeam Induces Mitochondrial Changes in Caenorhabditis elegans
Sleiman, Ahmad, Lalanne, Kévin, Vianna, François, Perrot, Yann, Richaud, Myriam, SenGupta, Tanima, Cardot-Martin, Mikaël, Pedini, Pascal, Picard, Christophe, Nilsen, Hilde, Galas, Simon, Adam-Guillermin, Christelle
Published in Biology (Basel, Switzerland) (09.06.2023)
Published in Biology (Basel, Switzerland) (09.06.2023)
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Journal Article
Constitutive MAP-kinase activation suppresses germline apoptosis in NTH-1 DNA glycosylase deficient C. elegans
Kassahun, Henok, SenGupta, Tanima, Schiavi, Alfonso, Maglioni, Silvia, Skjeldam, Hanne K., Arczewska, Katarzyna, Brockway, Nicole L., Estes, Suzanne, Eide, Lars, Ventura, Natascia, Nilsen, Hilde
Published in DNA repair (01.01.2018)
Published in DNA repair (01.01.2018)
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Journal Article
Preclinical validation of human recombinant glutamate-oxaloacetate transaminase for the treatment of acute ischemic stroke
Pérez-Mato, María, Dopico-López, Antonio, Akkoc, Yunus, López-Amoedo, Sonia, Correa-Paz, Clara, Candamo-Lourido, María, Iglesias-Rey, Ramón, López-Arias, Esteban, Bugallo-Casal, Ana, da Silva-Candal, Andrés, Bravo, Susana B., Chantada-Vázquez, María del Pilar, Arias, Susana, Santamaría-Cadavid, María, Estany-Gestal, Ana, Zaghmi, Ahlem, Gauthier, Marc A., Gutiérrez-Fernández, María, Martin, Abraham, Llop, Jordi, Rodríguez, Cristina, Almeida, Ángeles, Migliavacca, Martina, Polo, Ester, Pelaz, Beatriz, Gozuacik, Devrim, El Yamani, Naouale, SenGupta, Tanima, Rundén-Pran, Elise, Vivancos, José, Castellanos, Mar, Díez-Tejedor, Exuperio, Sobrino, Tomás, Rabinkov, Aharon, Mirelman, David, Castillo, José, Campos, Francisco
Published in iScience (15.11.2024)
Published in iScience (15.11.2024)
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Journal Article
Nicotinamide riboside first alleviates symptoms but later downregulates dopamine metabolism in proteasome inhibition mouse model of Parkinson's disease
Turconi, Giorgio, Alam, Farhan, SenGupta, Tanima, Pirnes-Karhu, Sini, Olfat, Soophie, Schmidt, Mark S., Mätlik, Kärt, Montaño-Rodriguez, Ana, Heiskanen, Vladimir, Garton, Daniel, Piepponen, Petteri T., Brenner, Charles, Holmberg, Carina I., Nilsen, Hilde, Pirinen, Eija, Andressoo, Jaan-Olle
Published in Heliyon (30.07.2024)
Published in Heliyon (30.07.2024)
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Journal Article
Cross-species functional genomic analysis identifies resistance genes of the histone deacetylase inhibitor valproic acid
Forthun, Rakel Brendsdal, Sengupta, Tanima, Skjeldam, Hanne Kim, Lindvall, Jessica Margareta, McCormack, Emmet, Gjertsen, Bjørn Tore, Nilsen, Hilde
Published in PloS one (14.11.2012)
Published in PloS one (14.11.2012)
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Journal Article
Loss of Caenorhabditis elegans UNG-1 uracil-DNA glycosylase affects apoptosis in response to DNA damaging agents
Skjeldam, Hanne K., Kassahun, Henok, Fensgård, Øyvind, SenGupta, Tanima, Babaie, Eshrat, Lindvall, Jessica M., Arczewska, Katarzyna, Nilsen, Hilde
Published in DNA repair (05.08.2010)
Published in DNA repair (05.08.2010)
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Journal Article
Base excision repair causes age-dependent accumulation of single-stranded DNA breaks that contribute to Parkinson disease pathology
SenGupta, Tanima, Palikaras, Konstantinos, Esbensen, Ying Q., Konstantinidis, Georgios, Galindo, Francisco Jose Naranjo, Achanta, Kavya, Kassahun, Henok, Stavgiannoudaki, Ioanna, Bohr, Vilhelm A., Akbari, Mansour, Gaare, Johannes, Tzoulis, Charalampos, Tavernarakis, Nektarios, Nilsen, Hilde
Published in Cell reports (Cambridge) (07.09.2021)
Published in Cell reports (Cambridge) (07.09.2021)
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Journal Article
Recent advances and current challenges of new approach methodologies in developmental and adult neurotoxicity testing
Serafini, Melania Maria, Sepehri, Sara, Midali, Miriam, Stinckens, Marth, Biesiekierska, Marta, Wolniakowska, Anna, Gatzios, Alexandra, Rundén-Pran, Elise, Reszka, Edyta, Marinovich, Marina, Vanhaecke, Tamara, Roszak, Joanna, Viviani, Barbara, SenGupta, Tanima
Published in Archives of toxicology (01.05.2024)
Published in Archives of toxicology (01.05.2024)
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Journal Article
Amelioration of Alzheimer’s disease pathology by mitophagy inducers identified via machine learning and a cross-species workflow
Xie, Chenglong, Zhuang, Xu-Xu, Niu, Zhangming, Ai, Ruixue, Lautrup, Sofie, Zheng, Shuangjia, Jiang, Yinghui, Han, Ruiyu, Gupta, Tanima Sen, Cao, Shuqin, Lagartos-Donate, Maria Jose, Cai, Cui-Zan, Xie, Li-Ming, Caponio, Domenica, Wang, Wen-Wen, Schmauck-Medina, Tomas, Zhang, Jianying, Wang, He-ling, Lou, Guofeng, Xiao, Xianglu, Zheng, Wenhua, Palikaras, Konstantinos, Yang, Guang, Caldwell, Kim A., Caldwell, Guy A., Shen, Han-Ming, Nilsen, Hilde, Lu, Jia-Hong, Fang, Evandro F.
Published in Nature biomedical engineering (01.01.2022)
Published in Nature biomedical engineering (01.01.2022)
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Journal Article
Uracil Accumulation and Mutagenesis Dominated by Cytosine Deamination in CpG Dinucleotides in Mice Lacking UNG and SMUG
Alsøe, Lene, Sarno, Antonio, Carracedo Huroz, Sergio, Domanska, Diana Ewa, Dingler, Felix, Lirussi, Lisa, Sengupta, Tanima, Tekin, Nuriye Basdag, Jobert, Laure, Alexandrov, Ludmil B, Galashevskaya, Anastasia, Rada, Cristina, Sandve, Geir Kjetil, Rognes, Torbjørn, Krokan, Hans Einar, Nilsen, Hilde Loge
Published in Scientific reports (01.12.2017)
Published in Scientific reports (01.12.2017)
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Journal Article
Krill oil protects dopaminergic neurons from age-related degeneration through temporal transcriptome rewiring and suppression of several hallmarks of aging
SenGupta, Tanima, Lefol, Yohan, Lirussi, Lisa, Suaste, Veronica, Luders, Torben, Gupta, Swapnil, Aman, Yahyah, Sharma, Kulbhushan, Fang, Evandro Fei, Nilsen, Hilde
Published in Aging (Albany, NY.) (15.11.2022)
Published in Aging (Albany, NY.) (15.11.2022)
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Journal Article
Targeted Central Nervous System Irradiation with Proton Microbeam Induces Mitochondrial Changes in ICaenorhabditis elegans/I
Sleiman, Ahmad, Lalanne, Kévin, Vianna, François, Perrot, Yann, Richaud, Myriam, SenGupta, Tanima, Cardot-Ma, Pedini, Pascal, Picard, Christophe, Nilsen, Hilde, Galas, Simon, Adam-Guillermin, Christelle
Published in Biology (Basel, Switzerland) (01.06.2023)
Published in Biology (Basel, Switzerland) (01.06.2023)
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Journal Article