A multi-center, phase Ib study of subcutaneous administration of isatuximab in combination with pomalidomide and dexamethasone in patients with relapsed/refractory multiple myeloma
Quach, Hang, Parmar, Gurdeep, Ocio, Enrique M, Prince, H Miles, Oriol, Albert, Crowther, Helen, Tsukada, Nobuhiro, Bories, Pierre, Madan, Sumit, Nathwani, Nitya, Sunami, Kazutaka, Semiond, Dorothee, Yu, Disa, Cordero, Paul, Macé, Sandrine, Suzan, Florence, Moreau, Philippe
Published in Haematologica (Roma) (15.08.2024)
Published in Haematologica (Roma) (15.08.2024)
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Drug‐Disease Interaction and Time‐Dependent Population Pharmacokinetics of Isatuximab in Relapsed/Refractory Multiple Myeloma Patients
Fau, Jean‐Baptiste, El‐Cheikh, Raouf, Brillac, Claire, Koiwai, Kimiko, Mace, Nathalie, Campana, Frank, Semiond, Dorothee, Nguyen, Laurent
Published in CPT: pharmacometrics and systems pharmacology (01.11.2020)
Published in CPT: pharmacometrics and systems pharmacology (01.11.2020)
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A phase 1b study of isatuximab plus pomalidomide/dexamethasone in relapsed/refractory multiple myeloma
Mikhael, Joseph, Richardson, Paul, Usmani, Saad Z., Raje, Noopur, Bensinger, William, Karanes, Chatchada, Campana, Frank, Kanagavel, Dheepak, Dubin, Franck, Liu, Qianying, Semiond, Dorothée, Anderson, Kenneth
Published in Blood (11.07.2019)
Published in Blood (11.07.2019)
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Phase I and Pharmacokinetic Study of XRP6258 (RPR 116258A), a Novel Taxane, Administered as a 1-Hour Infusion Every 3 Weeks in Patients with Advanced Solid Tumors
MITA, Alain C, DENIS, Louis J, SEMIOND, Dorothée, BESENVAL, Michèle, TOLCHER, Anthony W, ROWINSKY, Eric K, DEBONO, Johann S, GOETZ, Andrew D, OCHOA, Leonel, FOROUZESH, Bahram, BEERAM, Muralidhar, PATNAIK, Amita, MOLPUS, Kathleen
Published in Clinical cancer research (15.01.2009)
Published in Clinical cancer research (15.01.2009)
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A phase 2 study of isatuximab monotherapy in patients with multiple myeloma who are refractory to daratumumab
Mikhael, Joseph, Belhadj-Merzoug, Karim, Hulin, Cyrille, Vincent, Laure, Moreau, Philippe, Gasparetto, Cristina, Pour, Ludek, Spicka, Ivan, Vij, Ravi, Zonder, Jeffrey, Atanackovic, Djordje, Gabrail, Nashat, Martin, Thomas G., Perrot, Aurore, Bensfia, Samira, Weng, Qilong, Brillac, Claire, Semiond, Dorothée, Macé, Sandrine, Corzo, Kathryn P., Leleu, Xavier
Published in Blood cancer journal (New York) (12.05.2021)
Published in Blood cancer journal (New York) (12.05.2021)
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Discovery and Pharmacokinetic and Pharmacological Properties of the Potent and Selective MET Kinase Inhibitor 1‑{6-[6-(4-Fluorophenyl)-[1,2,4]triazolo[4,3‑b]pyridazin-3-ylsulfanyl]benzothiazol-2-yl}-3-(2-morpholin-4-ylethyl)urea (SAR125844)
Ugolini, Antonio, Kenigsberg, Mireille, Rak, Alexey, Vallée, Francois, Houtmann, Jacques, Lowinski, Maryse, Capdevila, Cécile, Khider, Jean, Albert, Eva, Martinet, Nathalie, Nemecek, Conception, Grapinet, Sandrine, Bacqué, Eric, Roesner, Manfred, Delaisi, Christine, Calvet, Loreley, Bonche, Fabrice, Semiond, Dorothée, Egile, Coumaran, Goulaouic, Hélène, Schio, Laurent
Published in Journal of medicinal chemistry (11.08.2016)
Published in Journal of medicinal chemistry (11.08.2016)
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Isatuximab Monotherapy for Desensitization in Highly Sensitized Patients Awaiting Kidney Transplant
Vincenti, Flavio, Bestard, Oriol, Brar, Amarpali, Cruzado, Josep M, Seron, Daniel, Gaber, A Osama, Ali, Nicole, Tambur, Anat R, Lee, Helen, Abbadessa, Giovanni, Paul, Jo-Anne, Dudek, Markus, Siegel, Ruby J, Torija, Alba, Semiond, Dorothee, Lépine, Lucie, Ternes, Nils, Montgomery, Robert A, Stegall, Mark
Published in Journal of the American Society of Nephrology (01.03.2024)
Published in Journal of the American Society of Nephrology (01.03.2024)
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Model‐based simulation to support the approval of isatuximab alone or with dexamethasone for the treatment of relapsed/refractory multiple myeloma in Japanese patients
Thai, Hoai‐Thu, Koiwai, Kimiko, Shitara, Yoshihisa, Kazama, Hirotaka, Fau, Jean‐Baptiste, Semiond, Dorothée, Veyrat‐Follet, Christine
Published in CPT: pharmacometrics and systems pharmacology (01.12.2023)
Published in CPT: pharmacometrics and systems pharmacology (01.12.2023)
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Journal Article
Joint modelling and simulation of M‐protein dynamics and progression‐free survival for alternative isatuximab dosing with pomalidomide/dexamethasone
Thai, Hoai‐Thu, Gaudel, Nadia, Cerou, Marc, Ayral, Geraldine, Fau, Jean‐Baptiste, Sebastien, Bernard, Velde, Helgi, Semiond, Dorothée, Veyrat‐Follet, Christine
Published in British journal of clinical pharmacology (01.05.2022)
Published in British journal of clinical pharmacology (01.05.2022)
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Population pharmacokinetics of cabazitaxel in patients with advanced solid tumors
Ferron, Géraldine M., Dai, Yang, Semiond, Dorothée
Published in Cancer chemotherapy and pharmacology (01.03.2013)
Published in Cancer chemotherapy and pharmacology (01.03.2013)
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PK/PD modeling analysis for dosing regimen selection of isatuximab as single agent and in combination therapy in patients with multiple myeloma
Koiwai, Kimiko, El‐Cheikh, Raouf, Thai, Hoai‐Thu, Brillac, Claire, Fau, Jean‐Baptiste, Veyrat‐Follet, Christine, Risse, Marie‐Laure, Velde, Helgi, Semiond, Dorothée, Nguyen, Laurent
Published in CPT: pharmacometrics and systems pharmacology (01.08.2021)
Published in CPT: pharmacometrics and systems pharmacology (01.08.2021)
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Phase I and Pharmacokinetic Study of Oral Irinotecan Given Once Daily for 5 Days Every 3 Weeks in Combination With Capecitabine in Patients With Solid Tumors
SOEPENBERG, Otto, DUMEZ, Herlinde, SPARREBOOM, Alex, VAN OOSTEROM, A. T, VERWEIJ, Jaap, SEMIOND, Dorothee, DEJONGE, Maja J. A, ESKENS, Ferry A. L. M, TER STEEG, Judith, SELLESLACH, Johan, ASSADOURIAN, Sylvie, SANDERINK, Ger-Jan
Published in Journal of clinical oncology (01.02.2005)
Published in Journal of clinical oncology (01.02.2005)
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Preclinical profile of cabazitaxel
Vrignaud, Patricia, Semiond, Dorothée, Benning, Veronique, Beys, Eric, Bouchard, Hervé, Gupta, Sunil
Published in Drug design, development and therapy (01.01.2014)
Published in Drug design, development and therapy (01.01.2014)
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Exposure‐response analyses for selection/confirmation of optimal isatuximab dosing regimen in combination with pomalidomide/dexamethasone treatment in patients with multiple myeloma
Rachedi, Fatiha, Koiwai, Kimiko, Gaudel‐Dedieu, Nadia, Sebastien, Bernard, Thai, Hoai‐Thu, Brillac, Claire, Fau, Jean Baptiste, Nguyen, Laurent, van de Velde, Helgi, Veyrat‐Follet, Christine, Semiond, Dorothée
Published in CPT: pharmacometrics and systems pharmacology (01.06.2022)
Published in CPT: pharmacometrics and systems pharmacology (01.06.2022)
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Journal Article
Abstract 1372: Model based approach to evaluate Isatuximab (Isa) monthly dosing regimen in relapsed/refractory multiple myeloma (RRMM)
Thai, Hoai-Thu, Gaudel-Dedieu, Nadia, Cerou, Marc, Sebastien, Bernard, van de Velde, Helgi, Semiond, Dorothee, Veyrat-Follet, Christine
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Model Based Approach to Evaluate Isatuximab Monthly Dosing Regimen in Relapsed/Refractory Multiple Myeloma Patients
Thai, Hoai-Thu, Gaudel-Dedieu, Nadia, Cerou, Marc, Sebastien, Bernard, van de Velde, Helgi, Semiond, Dorothee, Veyrat-Follet, Christine
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
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Journal Article
Preclinical Antitumor Activity of Cabazitaxel, a Semisynthetic Taxane Active in Taxane-Resistant Tumors
VRIGNAUD, Patricia, SEMIOND, Dorothée, LEJEUNE, Pascale, BOUCHARD, Hervé, CALVET, Loreley, COMBEAU, Cecile, RIOU, Jean-François, COMMERCON, Alain, LAVELLE, François, BISSERY, Marie-Christine
Published in Clinical cancer research (01.06.2013)
Published in Clinical cancer research (01.06.2013)
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Journal Article
Subcutaneous Isatuximab Administration By an on-Body Delivery System (OBDS) in Combination with Pomalidomide and Dexamethasone in Patients with Relapsed/Refractory Multiple Myeloma: Phase 1b Expansion Study Results
Quach, Hang, Parmar, Gurdeep, Ocio, Enrique M., Prince, H. Miles, Oriol, Albert, Tsukada, Nobuhiro, Sunami, Kazutaka, Bories, Pierre, Madan, Sumit, Semiond, Dorothee, Yu, Disa, Macé, Sandrine, Suzan, Florence, Moreau, Philippe
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
Subcutaneous (SC) isatuximab administration by an on-body delivery system (OBDS) in combination with pomalidomide-dexamethasone (Pd) in patients with relapsed/refractory multiple myeloma (RRMM): Interim phase 1b study results
Quach, Hang, Parmar, Gurdeep, Ocio, Enrique, Prince, H. Miles, Oriol Rocafiguera, Albert, Tsukada, Nobuhiro, Sunami, Kazutaka, Bories, Pierre, Karanes, Chatchada, Madan, Sumit, Semiond, Dorothee, Inchauspe, Marlene, Macé, Sandrine, Musholt, Petra B., Suzan, Florence, Moreau, Philippe
Published in Journal of clinical oncology (01.06.2022)
Published in Journal of clinical oncology (01.06.2022)
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