Photoaffinity labeling identifies an intersubunit steroid-binding site in heteromeric GABA type A (GABAA) receptors
Jayakar, Selwyn S., Chiara, David C., Zhou, Xiaojuan, Wu, Bo, Bruzik, Karol S., Miller, Keith W., Cohen, Jonathan B.
Published in The Journal of biological chemistry (14.08.2020)
Published in The Journal of biological chemistry (14.08.2020)
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Journal Article
Multiple Propofol-binding Sites in a γ-Aminobutyric Acid Type A Receptor (GABAAR) Identified Using a Photoreactive Propofol Analog
Jayakar, Selwyn S., Zhou, Xiaojuan, Chiara, David C., Dostalova, Zuzana, Savechenkov, Pavel Y., Bruzik, Karol S., Dailey, William P., Miller, Keith W., Eckenhoff, Roderic G., Cohen, Jonathan B.
Published in The Journal of biological chemistry (03.10.2014)
Published in The Journal of biological chemistry (03.10.2014)
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Journal Article
Exploring Ecological, Morphological, and Environmental Controls on Coastal Foredune Evolution at Annual Scales Using a Process-Based Model
Heminway, Selwyn S, Cohn, Nicholas, Davis, Elizabeth H, White, Andrew, Hein, Christopher J, Zinnert, Julie C
Published in Sustainability (01.04.2024)
Published in Sustainability (01.04.2024)
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Journal Article
Short intravenous amphotericin B followed by oral posaconazole using a simple, stratified treatment approach for diabetes or COVID-19-associated rhino-orbito-cerebral mucormycosis: a prospective cohort study
Manesh, Abi, Devasagayam, Emily, Bhanuprasad, Kundakarla, Varghese, Lalee, Kurien, Regi, Cherian, Lisa M., Dayanand, Divya, George, Mithun M., Kumar, Selwyn S., Karthik, Rajiv, Vanjare, Harshad, Peter, Jayanthi, Michael, Joy S., Thomas, Meera, Mathew, Binu S., Samuel, Prasanna, Peerawaranun, Pimnara, Mukaka, Mavuto, Rupa, Vedantam, Varghese, George M.
Published in Clinical microbiology and infection (01.10.2023)
Published in Clinical microbiology and infection (01.10.2023)
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Journal Article
Identifying Drugs that Bind Selectively to Intersubunit General Anesthetic Sites in the α 1 β 3 γ 2 GABA A R Transmembrane Domain
Jayakar, Selwyn S, Zhou, Xiaojuan, Chiara, David C, Jarava-Barrera, Carlos, Savechenkov, Pavel Y, Bruzik, Karol S, Tortosa, Mariola, Miller, Keith W, Cohen, Jonathan B
Published in Molecular pharmacology (01.06.2019)
Published in Molecular pharmacology (01.06.2019)
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Journal Article
Competitive Antagonism of Etomidate Action by Diazepam
McGrath, Megan, Hoyt, Helen, Pence, Andrea, Jayakar, Selwyn S, Zhou, Xiaojuan, Forman, Stuart A, Cohen, Jonathan B, Miller, Keith W, Raines, Douglas E
Published in Anesthesiology (Philadelphia) (01.09.2020)
Published in Anesthesiology (Philadelphia) (01.09.2020)
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Journal Article
Competitive Antagonism of Etomidate Action by Diazepam: In Vitro GABAA Receptor and In Vivo Zebrafish Studies
McGrath, Megan, Hoyt, Helen, Pence, Andrea, Jayakar, Selwyn S., Zhou, Xiaojuan, Forman, Stuart A., Cohen, Jonathan B., Miller, Keith W., Raines, Douglas E.
Published in Anesthesiology (Philadelphia) (01.09.2020)
Published in Anesthesiology (Philadelphia) (01.09.2020)
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Journal Article
Human OPRM1 and murine Oprm1 promoter driven viral constructs for genetic access to μ-opioidergic cell types
Salimando, Gregory J., Tremblay, Sébastien, Kimmey, Blake A., Li, Jia, Rogers, Sophie A., Wojick, Jessica A., McCall, Nora M., Wooldridge, Lisa M., Rodrigues, Amrith, Borner, Tito, Gardiner, Kristin L., Jayakar, Selwyn S., Singeç, Ilyas, Woolf, Clifford J., Hayes, Matthew R., De Jonghe, Bart C., Bennett, F. Christian, Bennett, Mariko L., Blendy, Julie A., Platt, Michael L., Creasy, Kate Townsend, Renthal, William R., Ramakrishnan, Charu, Deisseroth, Karl, Corder, Gregory
Published in Nature communications (13.09.2023)
Published in Nature communications (13.09.2023)
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Journal Article
Etomidate and Etomidate Analog Binding and Positive Modulation of γ-Aminobutyric Acid Type A Receptors: Evidence for a State-dependent Cutoff Effect
McGrath, Megan, Yu, Zhiyi, Jayakar, Selwyn S, Ma, Celena, Tolia, Mansi, Zhou, Xiaojuan, Miller, Keith W, Cohen, Jonathan B, Raines, Douglas E
Published in Anesthesiology (Philadelphia) (01.11.2018)
Published in Anesthesiology (Philadelphia) (01.11.2018)
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Journal Article
Orthosteric and Allosteric Ligands of Nicotinic Acetylcholine Receptors for Smoking Cessation
Mohamed, Tasnim S, Jayakar, Selwyn S, Hamouda, Ayman K
Published in Frontiers in molecular neuroscience (25.11.2015)
Published in Frontiers in molecular neuroscience (25.11.2015)
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Journal Article
Competitive Antagonism of Anesthetic Action at the γ-Aminobutyric Acid Type A Receptor by a Novel Etomidate Analog with Low Intrinsic Efficacy
Ma, Celena, Pejo, Ervin, McGrath, Megan, Jayakar, Selwyn S, Zhou, Xiaojuan, Miller, Keith W, Cohen, Jonathan B, Raines, Douglas E
Published in Anesthesiology (Philadelphia) (01.11.2017)
Published in Anesthesiology (Philadelphia) (01.11.2017)
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Journal Article
Inhibitable photolabeling by neurosteroid diazirine analog in the β3-Subunit of human hetereopentameric type A GABA receptors
Wu, Bo, Jayakar, Selwyn S., Zhou, Xiaojuan, Titterton, Katherine, Chiara, David C., Szabo, Andrea L., Savechenkov, Pavel Y., Kent, Daniel E., Cohen, Jonathan B., Forman, Stuart A., Miller, Keith W., Bruzik, Karol S.
Published in European journal of medicinal chemistry (15.01.2019)
Published in European journal of medicinal chemistry (15.01.2019)
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Journal Article
PACAP induces plasticity at autonomic synapses by nAChR-dependent NOS1 activation and AKAP-mediated PKA targeting
Jayakar, Selwyn S., Pugh, Phyllis C., Dale, Zack, Starr, Eric R., Cole, Samantha, Margiotta, Joseph F.
Published in Molecular and cellular neuroscience (01.11.2014)
Published in Molecular and cellular neuroscience (01.11.2014)
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Journal Article
Identifying Drugs that Bind Selectively to Intersubunit General Anesthetic Sites in the α1β3γ2 GABAAR Transmembrane Domain
Jayakar, Selwyn S, Zhou, Xiaojuan, Chiara, David C, Jarava-Barrera, Carlos, Savechenkov, Pavel Y, Bruzik, Karol S, Tortosa, Mariola, Miller, Keith W, Cohen, Jonathan B
Published in Molecular pharmacology (01.06.2019)
Published in Molecular pharmacology (01.06.2019)
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Journal Article
Photoaffinity Labeling of Nicotinic Receptors: Diversity of Drug Binding Sites
Hamouda, Ayman K, Jayakar, Selwyn S, Chiara, David C, Cohen, Jonathan B
Published in Journal of molecular neuroscience (01.07.2014)
Published in Journal of molecular neuroscience (01.07.2014)
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Journal Article
Positive and Negative Allosteric Modulation of an α1β3γ2 γ-Aminobutyric Acid Type A (GABAA) Receptor by Binding to a Site in the Transmembrane Domain at the γ+-β− Interface
Jayakar, Selwyn S., Zhou, Xiaojuan, Savechenkov, Pavel Y., Chiara, David C., Desai, Rooma, Bruzik, Karol S., Miller, Keith W., Cohen, Jonathan B.
Published in The Journal of biological chemistry (18.09.2015)
Published in The Journal of biological chemistry (18.09.2015)
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