EWS–FLI1 modulated alternative splicing of ARID1A reveals novel oncogenic function through the BAF complex
Selvanathan, Saravana P, Graham, Garrett T, Grego, Alexander R, Baker, Tabari M, Hogg, J Robert, Simpson, Mark, Batish, Mona, Crompton, Brian, Stegmaier, Kimberly, Tomazou, Eleni M, Kovar, Heinrich, Üren, Aykut, Toretsky, Jeffrey A
Published in Nucleic acids research (10.10.2019)
Published in Nucleic acids research (10.10.2019)
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HOMO Level Pinning in Molecular Junctions: Joint Theoretical and Experimental Evidence
Rodriguez-Gonzalez, S, Xie, Z, Galangau, O, Selvanathan, P, Norel, L, Van Dyck, C, Costuas, K, Frisbie, C. D, Rigaut, S, Cornil, J
Published in The journal of physical chemistry letters (03.05.2018)
Published in The journal of physical chemistry letters (03.05.2018)
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Oncogenic fusion protein EWS-FLI1 is a network hub that regulates alternative splicing
Selvanathan, Saravana P., Graham, Garrett T., Erkizan, Hayriye V., Dirksen, Uta, Natarajan, Thanemozhi G., Dakic, Aleksandra, Yu, Songtao, Liu, Xuefeng, Paulsen, Michelle T., Ljungman, Mats E., Wu, Cathy H., Lawlor, Elizabeth R., Üren, Aykut, Toretsky, Jeffrey A.
Published in Proceedings of the National Academy of Sciences - PNAS (17.03.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (17.03.2015)
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Ezrin Binds to DEAD-Box RNA Helicase DDX3 and Regulates Its Function and Protein Level
Çelik, Haydar, Sajwan, Kamal P., Selvanathan, Saravana P., Marsh, Benjamin J., Pai, Amrita V., Kont, Yasemin Saygideger, Han, Jenny, Minas, Tsion Z., Rahim, Said, Erkizan, Hayriye Verda, Toretsky, Jeffrey A., Üren, Aykut
Published in Molecular and cellular biology (01.09.2015)
Published in Molecular and cellular biology (01.09.2015)
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Single enantiomer of YK-4-279 demonstrates specificity in targeting the oncogene EWS-FLI1
Barber-Rotenberg, Julie S, Selvanathan, Saravana P, Kong, Yali, Erkizan, Hayriye V, Snyder, Tara M, Hong, S Peter, Kobs, Christina L, South, Natalie L, Summer, Steven, Monroe, Philip J, Chruszcz, Maksymilian, Dobrev, Veselin, Tosso, Perrer N, Scher, Lauren J, Minor, Wladek, Brown, Milton L, Metallo, Steven J, Üren, Aykut, Toretsky, Jeffrey A
Published in Oncotarget (29.02.2012)
Published in Oncotarget (29.02.2012)
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The ETS Inhibitors YK-4-279 and TK-216 Are Novel Antilymphoma Agents
Spriano, Filippo, Chung, Elaine Yee Lin, Gaudio, Eugenio, Tarantelli, Chiara, Cascione, Luciano, Napoli, Sara, Jessen, Katti, Carrassa, Laura, Priebe, Valdemar, Sartori, Giulio, Graham, Garrett, Selvanathan, Saravana P, Cavalli, Andrea, Rinaldi, Andrea, Kwee, Ivo, Testoni, Monica, Genini, Davide, Ye, B Hilda, Zucca, Emanuele, Stathis, Anastasios, Lannutti, Brian, Toretsky, Jeffrey A, Bertoni, Francesco
Published in Clinical cancer research (15.08.2019)
Published in Clinical cancer research (15.08.2019)
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The Nuclear Export Signal of Splicing Factor Uap56p Interacts with Nuclear Pore-associated Protein Rae1p for mRNA Export in Schizosaccharomyces pombe
Thakurta, Anjan G., Selvanathan, Saravana P., Patterson, Andrew D., Gopal, Ganesh, Dhar, Ravi
Published in The Journal of biological chemistry (15.06.2007)
Published in The Journal of biological chemistry (15.06.2007)
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Widespread hypertranscription in aggressive human cancers
Zatzman, Matthew, Fuligni, Fabio, Ripsman, Ryan, Suwal, Tannu, Comitani, Federico, Edward, Lisa-Monique, Denroche, Rob, Jang, Gun Ho, Notta, Faiyaz, Gallinger, Steven, Selvanathan, Saravana P, Toretsky, Jeffrey A, Hellmann, Matthew D, Tabori, Uri, Huang, Annie, Shlien, Adam
Published in Science advances (25.11.2022)
Published in Science advances (25.11.2022)
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Comprehensive profiling of mRNA splicing indicates that GC content signals altered cassette exon inclusion in Ewing sarcoma
Graham, Garrett T, Selvanathan, Saravana P, Zöllner, Stefan K, Stahl, Emily, Shlien, Adam, Caplen, Natasha J, Üren, Aykut, Toretsky, Jeffrey A
Published in NAR cancer (01.03.2022)
Published in NAR cancer (01.03.2022)
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Inhibition of the oncogenic fusion protein EWS-FLI1 causes G 2 -M cell cycle arrest and enhanced vincristine sensitivity in Ewing's sarcoma
Zöllner, Stefan K, Selvanathan, Saravana P, Graham, Garrett T, Commins, Ryan M T, Hong, Sung Hyeok, Moseley, Eric, Parks, Sydney, Haladyna, Jessica N, Erkizan, Hayriye V, Dirksen, Uta, Hogarty, Michael D, Üren, Aykut, Toretsky, Jeffrey A
Published in Science signaling (03.10.2017)
Published in Science signaling (03.10.2017)
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Schizosaccharomyces pombe Dss1p Is a DNA Damage Checkpoint Protein That Recruits Rad24p, Cdc25p, and Rae1p to DNA Double-strand Breaks
Selvanathan, Saravana P., Thakurta, Anjan G., Dhakshnamoorthy, Jothy, Zhou, Ming, Veenstra, Timothy D., Dhar, Ravi
Published in The Journal of biological chemistry (07.05.2010)
Published in The Journal of biological chemistry (07.05.2010)
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Journal Article
Abstract 694: TK-216: a novel, first-in-class, small molecule inhibitor of EWS-FLI1 in early clinical development, for the treatment of Ewing Sarcoma
Selvanathan, Saravana P., Moseley, Eric, Graham, Garrett T., Jessen, Katti, Lannutti, Brian, Üren, Aykut, Toretsky, Jeffrey A.
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Abstract LB177: Widespread hypertranscription in aggressive human cancer
Zatzman, Matthew, Fuligni, Fabio, Ripsman, Ryan, Suwal, Tannu, Edward, Lisa-Monique, Denroche, Rob, Jang, Gun Ho, Notta, Faiyaz, Gallinger, Steven, Selvanathan, Saravana P., Toretsky, Jeffrey, Hellmann, Matthew D., Tabori, Uri, Huang, Annie, Shlien, Adam
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Author Correction: A large-scale test of the link between intergroup contact and support for social change
Hässler, Tabea, Ullrich, Johannes, Bernardino, Michelle, Shnabel, Nurit, Laar, Colette Van, Valdenegro, Daniel, Sebben, Simone, Tropp, Linda R., Visintin, Emilio Paolo, González, Roberto, Ditlmann, Ruth K., Abrams, Dominic, Selvanathan, Hema Preya, Brankovic, Marija, Wright, Stephen, von Zimmermann, Jorina, Pasek, Michael, Aydin, Anna Lisa, Žeželj, Iris, Pereira, Adrienne, Lantos, Nóra Anna, Sainz, Mario, Glenz, Andreas, Oberpfalzerová, Hana, Bilewicz, Michal, Kende, Anna, Kuzawinska, Olga, Otten, Sabine, Maloku, Edona, Noor, Masi, Gul, Pelin, Pistella, Jessica, Baiocco, Roberto, Jelic, Margareta, Osin, Evgeny, Bareket, Orly, Biruski, Dinka Corkalo, Cook, Jonathan E., Dawood, Maneeza, Droogendyk, Lisa, Loyo, Angélica Herrera, Kelmendi, Kaltrina, Ugarte, Luiza Mugnol
Published in Nature human behaviour (01.07.2020)
Published in Nature human behaviour (01.07.2020)
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