Structure–Activity Relationships of cyclo(l‑Tyrosyl‑l‑tyrosine) Derivatives Binding to Mycobacterium tuberculosis CYP121: Iodinated Analogues Promote Shift to High-Spin Adduct
Rajput, Sunnia, McLean, Kirsty J, Poddar, Harshwardhan, Selvam, Irwin R, Nagalingam, Gayathri, Triccas, James A, Levy, Colin W, Munro, Andrew W, Hutton, Craig A
Published in Journal of medicinal chemistry (14.11.2019)
Published in Journal of medicinal chemistry (14.11.2019)
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A new strategy for hit generation: Novel in cellulo active inhibitors of CYP121A1 from Mycobacterium tuberculosis via a combined X-ray crystallographic and phenotypic screening approach (XP screen)
Frederickson, Martyn, Selvam, Irwin R., Evangelopoulos, Dimitrios, McLean, Kirsty J., Katariya, Mona M., Tunnicliffe, Richard B., Campbell, Bethany, Kavanagh, Madeline E., Charoensutthivarakul, Sitthivut, Blankley, Richard T., Levy, Colin W., de Carvalho, Luiz Pedro S., Leys, David, Munro, Andrew W., Coyne, Anthony G., Abell, Chris
Published in European journal of medicinal chemistry (15.02.2022)
Published in European journal of medicinal chemistry (15.02.2022)
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