Pharmacokinetics of darunavir/ritonavir and ketoconazole following co‐administration in HIV–healthy volunteers
Sekar, Vanitha J., Lefebvre, Eric, De Pauw, Martine, Vangeneugden, Tony, Hoetelmans, Richard M.
Published in British journal of clinical pharmacology (01.08.2008)
Published in British journal of clinical pharmacology (01.08.2008)
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Pharmacokinetics of Darunavir/Ritonavir and Rifabutin Coadministered in HIV-Negative Healthy Volunteers
Sekar, Vanitha, Lavreys, Ludo, Van de Casteele, Tom, Berckmans, Cindy, Spinosa-Guzman, Sabrina, Vangeneugden, Tony, De Pauw, Martine, Hoetelmans, Richard
Published in Antimicrobial Agents and Chemotherapy (01.10.2010)
Published in Antimicrobial Agents and Chemotherapy (01.10.2010)
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Pharmacokinetic Interactions of Maraviroc with Darunavir-Ritonavir, Etravirine, and Etravirine-Darunavir-Ritonavir in Healthy Volunteers: Results of Two Drug Interaction Trials
KAKUDA, Thomas N, ABEL, Samantha, TWEEDY, Sarah, HOETELMANS, Richard M. W, DAVIS, John, HAMLIN, Julia, SCHÖLLER-GYÜRE, Monika, MACK, Rebecca, NDONGO, Noella, PETIT, Wendy, RIDGWAY, Caroline, SEKAR, Vanitha
Published in Antimicrobial Agents and Chemotherapy (01.05.2011)
Published in Antimicrobial Agents and Chemotherapy (01.05.2011)
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The effect of different meal types on the pharmacokinetics of darunavir (TMC114)/ritonavir in HIV-negative healthy volunteers
Sekar, Vanitha, Kestens, Dries, Spinosa-Guzman, Sabrina, De Pauw, Martine, De Paepe, Els, Vangeneugden, Tony, Lefebvre, Eric, Hoetelmans, Richard M W
Published in Journal of clinical pharmacology (01.04.2007)
Published in Journal of clinical pharmacology (01.04.2007)
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Pharmacokinetic Interaction between Darunavir Boosted with Ritonavir and Omeprazole or Ranitidine in Human Immunodeficiency Virus-Negative Healthy Volunteers
SEKAR, Vanitha J, LEFEBVRE, Eric, DE PAEPE, Els, DE MAREZ, Tine, DE PAUW, Martine, PARYS, Wim, HOETELMANS, Richard M. W
Published in Antimicrobial Agents and Chemotherapy (01.03.2007)
Published in Antimicrobial Agents and Chemotherapy (01.03.2007)
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Pharmacokinetic interaction between TMC114/ritonavir and tenofovir disoproxil fumarate in healthy volunteers
Hoetelmans, Richard M. W., Mariën, Kris, De Pauw, Martine, Hill, Andrew, Peeters, Monika, Sekar, Vanitha, De Doncker, Piet, Woodfall, Brian, Lefebvre, Eric
Published in British journal of clinical pharmacology (01.11.2007)
Published in British journal of clinical pharmacology (01.11.2007)
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Pharmacokinetics and Pharmacodynamics of Darunavir and Etravirine in HIV-1-Infected, Treatment-Experienced Patients in the Gender, Race, and Clinical Experience (GRACE) Trial
Mrus, Joseph, Anderson, David, Ryan, Robert, De La Rosa, Guy, Coate, Bruce, Vis, Peter, Kakuda, Thomas, Sekar, Vanitha
Published in AIDS Research and Treatment (01.01.2012)
Published in AIDS Research and Treatment (01.01.2012)
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Pharmacokinetic interaction between ethinyl estradiol, norethindrone and darunavir with low-dose ritonavir in healthy women
SEKAR, Vanitha J, LEFEBVRE, Eric, SPINOSA GUZMAN, Sabrina, FELICIONE, Elise, DE PAUW, Martine, VANGENEUGDEN, Tony, HOETELMANS, Richard M. W
Published in Antiviral therapy (01.01.2008)
Published in Antiviral therapy (01.01.2008)
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Pharmacokinetic interaction between TMC114/r and efavirenz in healthy volunteers
SEKAR, Vanitha J, DE PAUW, Martine, MARIËN, Kris, PEETERS, Monika, LEFEBVRE, Eric, HOETELMANS, Richard M. W
Published in Antiviral therapy (01.01.2007)
Published in Antiviral therapy (01.01.2007)
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Darunavir/ritonavir pharmacokinetics following coadministration with clarithromycin in healthy volunteers
Sekar, Vanitha J, Spinosa-Guzman, Sabrina, De Paepe, Els, De Pauw, Martine, Vangeneugden, Tony, Lefebvre, Eric, Hoetelmans, Richard M W
Published in Journal of clinical pharmacology (01.01.2008)
Published in Journal of clinical pharmacology (01.01.2008)
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Pharmacokinetics of darunavir (TMC114) and atazanavir during coadministration in HIV-negative, healthy volunteers
Sekar, Vanitha J, Lefebvre, Eric, De Marez, Tine, Spinosa-Guzman, Sabrina, De Pauw, Martine, De Paepe, Els, Vangeneugden, Tony, Hoetelmans, Richard M W
Published in Drugs in R&D (2007)
Published in Drugs in R&D (2007)
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Once‐daily simeprevir (TMC435) with pegylated interferon and ribavirin in treatment‐naïve genotype 1 hepatitis C: The randomized PILLAR study
Fried, Michael W., Buti, Maria, Dore, Gregory J., Flisiak, Robert, Ferenci, Peter, Jacobson, Ira, Marcellin, Patrick, Manns, Michael, Nikitin, Igor, Poordad, Fred, Sherman, Morris, Zeuzem, Stefan, Scott, Jane, Gilles, Leen, Lenz, Oliver, Peeters, Monika, Sekar, Vanitha, Smedt, Goedele, Beumont‐Mauviel, Maria
Published in Hepatology (Baltimore, Md.) (01.12.2013)
Published in Hepatology (Baltimore, Md.) (01.12.2013)
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Simeprevir Increases Rate of Sustained Virologic Response Among Treatment-Experienced Patients With HCV Genotype-1 Infection: A Phase IIb Trial
Zeuzem, Stefan, Berg, Thomas, Gane, Edward, Ferenci, Peter, Foster, Graham R, Fried, Michael W, Hezode, Christophe, Hirschfield, Gideon M, Jacobson, Ira, Nikitin, Igor, Pockros, Paul J, Poordad, Fred, Scott, Jane, Lenz, Oliver, Peeters, Monika, Sekar, Vanitha, De Smedt, Goedele, Sinha, Rekha, Beumont-Mauviel, Maria
Published in Gastroenterology (New York, N.Y. 1943) (01.02.2014)
Published in Gastroenterology (New York, N.Y. 1943) (01.02.2014)
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Antiviral activity of TMC435 monotherapy in patients infected with HCV genotypes 2–6: TMC435-C202, a phase IIa, open-label study
Moreno, Christophe, Berg, Thomas, Tanwandee, Tawesak, Thongsawat, Satawat, Van Vlierberghe, Hans, Zeuzem, Stefan, Lenz, Oliver, Peeters, Monika, Sekar, Vanitha, De Smedt, Goedele
Published in Journal of hepatology (01.06.2012)
Published in Journal of hepatology (01.06.2012)
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Once-daily darunavir/ritonavir vs. lopinavir/ritonavir in treatment-naive, HIV-1-infected patients: 96-week analysis
MILLS, Anthony M, NELSON, Mark, LAVREYS, Ludo, JAYAWEERA, Dushyantha, RUXRUNGTHAM, Kiat, CASSETTI, Isabel, GIRARD, Pierre-Marie, WORKMAN, Cassy, DIERYNCK, Inge, SEKAR, Vanitha, VANDEN ABEELE, Carline
Published in AIDS (London) (24.08.2009)
Published in AIDS (London) (24.08.2009)
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Rapid viral response of once-daily TMC435 plus pegylated interferon/ribavirin in hepatitis C genotype-1 patients: a randomized trial
MANNS, Michael, REESINK, Henk, SEKAR, Vanitha, SIMMEN, Kenneth, VERLOES, Rene, BERG, Thomas, DUSHEIKO, Geoffrey, FLISIAK, Robert, MARCELLIN, Patrick, MORENO, Christophe, LENZ, Oliver, MEYVISCH, Paul, PEETERS, Monika
Published in Antiviral therapy (01.01.2011)
Published in Antiviral therapy (01.01.2011)
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Pharmacokinetics, safety and efficacy of darunavir/ ritonavir in treatment-experienced children and adolescents
BLANCHE, Stéphane, BOLOGNA, Rosa, SPINOSA-GUZMAN, Sabrina, CAHN, Pedro, RUGINA, Sorin, FLYNN, Patricia, FORTUNY, Claudia, VIS, Peter, SEKAR, Vanitha, VAN BAELEN, Ben, DIERYNCK, Inge
Published in AIDS (London) (24.09.2009)
Published in AIDS (London) (24.09.2009)
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Suboptimal adherence to darunavir/ritonavir has minimal effect on efficacy compared with lopinavir/ritonavir in treatment-naive, HIV-infected patients: 96 week ARTEMIS data
Nelson, Mark, Girard, Pierre-Marie, DeMasi, Ralph, Chen, Liddy, Smets, Erik, Sekar, Vanitha, Lavreys, Ludo
Published in Journal of antimicrobial chemotherapy (01.07.2010)
Published in Journal of antimicrobial chemotherapy (01.07.2010)
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Pharmacokinetics of darunavir/ritonavir and TMC125 alone and coadministered in HIV-negative volunteers
SCHÖLLER-GYÜRE, Monika, KAKUDA, Thomas N, SEKAR, Vanitha, WOODFALL, Brian, DE SMEDT, Goedele, LEFEBVRE, Eric, PEETERS, Monika, HOETELMANS, Richard M
Published in Antiviral therapy (01.01.2007)
Published in Antiviral therapy (01.01.2007)
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