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Published in Cell reports (Cambridge) (09.04.2019)
Published in Cell reports (Cambridge) (09.04.2019)
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Delaying aging and the aging-associated decline in protein homeostasis by inhibition of tryptophan degradation
van der Goot, Annemieke T, Zhu, Wentao, Vázquez-Manrique, Rafael P, Seinstra, Renée I, Dettmer, Katja, Michels, Helen, Farina, Francesca, Krijnen, Jasper, Melki, Ronald, Buijsman, Rogier C, Ruiz Silva, Mariana, Thijssen, Karen L, Kema, Ido P, Neri, Christian, Oefner, Peter J, Nollen, Ellen A. A
Published in Proceedings of the National Academy of Sciences - PNAS (11.09.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (11.09.2012)
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Assessing motor-related phenotypes of Caenorhabditis elegans with the wide field-of-view nematode tracking platform
Koopman, Mandy, Peter, Quentin, Seinstra, Renée I., Perni, Michele, Vendruscolo, Michele, Dobson, Christopher M., Knowles, Tuomas P. J., Nollen, Ellen A. A.
Published in Nature protocols (01.06.2020)
Published in Nature protocols (01.06.2020)
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Rebalancing the motor circuit restores movement in a Caenorhabditis elegans model for TDP-43 toxicity
Koopman, Mandy, Güngördü, Lale, Janssen, Leen, Seinstra, Renée I., Richmond, Janet E., Okerlund, Nathan, Wardenaar, René, Islam, Priota, Hogewerf, Wytse, Brown, Andre E.X., Jorgensen, Erik M., Nollen, Ellen A.A.
Published in Cell reports (Cambridge) (28.05.2024)
Published in Cell reports (Cambridge) (28.05.2024)
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Discovery and functional prioritization of Parkinson's disease candidate genes from large-scale whole exome sequencing
Jansen, Iris E, Ye, Hui, Heetveld, Sasja, Lechler, Marie C, Michels, Helen, Seinstra, Renée I, Lubbe, Steven J, Drouet, Valérie, Lesage, Suzanne, Majounie, Elisa, Gibbs, J Raphael, Nalls, Mike A, Ryten, Mina, Botia, Juan A, Vandrovcova, Jana, Simon-Sanchez, Javier, Castillo-Lizardo, Melissa, Rizzu, Patrizia, Blauwendraat, Cornelis, Chouhan, Amit K, Li, Yarong, Yogi, Puja, Amin, Najaf, van Duijn, Cornelia M, Morris, Huw R, Brice, Alexis, Singleton, Andrew B, David, Della C, Nollen, Ellen A, Jain, Shushant, Shulman, Joshua M, Heutink, Peter
Published in Genome Biology (30.01.2017)
Published in Genome Biology (30.01.2017)
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Nuclear/Cytoplasmic Fractionation of Proteins from Caenorhabditis elegans
Mata-Cabana, Alejandro, Sin, Olga, Seinstra, Renée I, Nollen, Ellen A A
Published in Bio-protocol (20.10.2018)
Published in Bio-protocol (20.10.2018)
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Identification of an RNA Polymerase III Regulator Linked to Disease-Associated Protein Aggregation
Sin, Olga, de Jong, Tristan, Mata-Cabana, Alejandro, Kudron, Michelle, Zaini, Mohamad Amr, Aprile, Francesco A., Seinstra, Renée I., Stroo, Esther, Prins, Roméo Willinge, Martineau, Céline N., Wang, Hai Hui, Hogewerf, Wytse, Steinhof, Anne, Wanker, Erich E., Vendruscolo, Michele, Calkhoven, Cornelis F., Reinke, Valerie, Guryev, Victor, Nollen, Ellen A.A.
Published in Molecular cell (16.03.2017)
Published in Molecular cell (16.03.2017)
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Identification of an evolutionary conserved structural loop that is required for the enzymatic and biological function of tryptophan 2,3-dioxygenase
Michels, Helen, Seinstra, Renée I., Uitdehaag, Joost C. M., Koopman, Mandy, van Faassen, Martijn, Martineau, Céline N., Kema, Ido P., Buijsman, Rogier, Nollen, Ellen A. A.
Published in Scientific reports (20.12.2016)
Published in Scientific reports (20.12.2016)
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Comparative Studies in the A30P and A53T α-Synuclein C. elegans Strains to Investigate the Molecular Origins of Parkinson's Disease
Perni, Michele, van der Goot, Annemieke, Limbocker, Ryan, van Ham, Tjakko J, Aprile, Francesco A, Xu, Catherine K, Flagmeier, Patrick, Thijssen, Karen, Sormanni, Pietro, Fusco, Giuliana, Chen, Serene W, Challa, Pavan K, Kirkegaard, Julius B, Laine, Romain F, Ma, Kai Yu, Müller, Martin B D, Sinnige, Tessa, Kumita, Janet R, Cohen, Samuel I A, Seinstra, Renée, Kaminski Schierle, Gabriele S, Kaminski, Clemens F, Barbut, Denise, De Simone, Alfonso, Knowles, Tuomas P J, Zasloff, Michael, Nollen, Ellen A A, Vendruscolo, Michele, Dobson, Christopher M
Published in Frontiers in cell and developmental biology (22.03.2021)
Published in Frontiers in cell and developmental biology (22.03.2021)
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The cellular modifier MOAG‐4/SERF drives amyloid formation through charge complementation
Pras, Anita, Houben, Bert, Aprile, Francesco A, Seinstra, Renée, Gallardo, Rodrigo, Janssen, Leen, Hogewerf, Wytse, Gallrein, Christian, De Vleeschouwer, Matthias, Mata‐Cabana, Alejandro, Koopman, Mandy, Stroo, Esther, de Vries, Minke, Louise Edwards, Samantha, Kirstein, Janine, Vendruscolo, Michele, Falsone, Salvatore Fabio, Rousseau, Frederic, Schymkowitz, Joost, Nollen, Ellen A A
Published in The EMBO journal (02.11.2021)
Published in The EMBO journal (02.11.2021)
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Abstract 2036: Forced activation of Cdk1 via Wee-1 inhibition impairs homologous recombination in breast cancer cells
Van Vugt, Marcel A., Krajewska, Malgosia, Bisselink, Yvette, Seinstra, Renee I., Sillje, Herman H., de Vries, Elisabeth G.
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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The cellular modifier MOAG-4/SERF drives amyloid formation through charge complementation
Pras, Anita, Houben, Bert, Aprile, Francesco A, Seinstra, Renée, Gallardo, Rodrigo, Janssen, Leen, Hogewerf, Wytse, De Vleeschouwer, Matthias, Mata-Cabana, Alejandro, Koopman, Mandy, Stroo, Esther, Minke De Vries, Edwards, Samantha Louise, Vendruscolo, Michele, Falsone, S Fabio, Rousseau, Frederic, Schymkowitz, Joost, Nollen, Ellen A A
Published in bioRxiv (21.12.2020)
Published in bioRxiv (21.12.2020)
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