Immune checkpoint inhibitor treatment and atherosclerotic cardiovascular disease: an emerging clinical problem
Poels, Kikkie, Neppelenbroek, Suzanne I.M., Kersten, Marie José, Antoni, M. Louisa, Lutgens, Esther, Seijkens, Tom T.P.
Published in Journal for immunotherapy of cancer (01.06.2021)
Published in Journal for immunotherapy of cancer (01.06.2021)
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Journal Article
Short-term regulation of hematopoiesis by lipoprotein(a) results in the production of pro-inflammatory monocytes
Schnitzler, Johan G., Poels, Kikkie, Stiekema, Lotte C.A., Yeang, Calvin, Tsimikas, Sotirios, Kroon, Jeffrey, Stroes, Erik S.G., Lutgens, Esther, Seijkens, Tom T.P.
Published in International journal of cardiology (15.09.2020)
Published in International journal of cardiology (15.09.2020)
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Journal Article
CD40L Deficiency Protects Against Aneurysm Formation
Kusters, Pascal J.H, Seijkens, Tom T.P, Beckers, Linda, Lievens, Dirk, Winkels, Holger, de Waard, Vivian, Duijvestijn, Adriaan, Lindquist Liljeqvist, Moritz, Roy, Joy, Daugherty, Alan, Newby, Andrew, Gerdes, Norbert, Lutgens, Esther
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2018)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2018)
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Journal Article
Antibody-Mediated Inhibition of CTLA4 Aggravates Atherosclerotic Plaque Inflammation and Progression in Hyperlipidemic Mice
Poels, Kikkie, van Leent, Mandy M T, Reiche, Myrthe E, Kusters, Pascal J H, Huveneers, Stephan, de Winther, Menno P J, Mulder, Willem J M, Lutgens, Esther, Seijkens, Tom T P
Published in Cells (Basel, Switzerland) (29.08.2020)
Published in Cells (Basel, Switzerland) (29.08.2020)
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Journal Article
T cell specific deletion of Casitas B lineage lymphoma-b reduces atherosclerosis, but increases plaque T cell infiltration and systemic T cell activation
Vos, Winnie G, van Os, Bram W, den Toom, Myrthe, Beckers, Linda, van Roomen, Cindy P A A, van Tiel, Claudia M, Mohapatra, Bhopal C, Band, Hamid, Nitz, Katrin, Weber, Christian, Atzler, Dorothee, de Winther, Menno P J, Bosmans, Laura A, Lutgens, Esther, Seijkens, Tom T P
Published in Frontiers in immunology (04.03.2024)
Published in Frontiers in immunology (04.03.2024)
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Journal Article
Exploring immune checkpoints as potential therapeutic targets in atherosclerosis
Kusters, Pascal J H, Lutgens, Esther, Seijkens, Tom T P
Published in Cardiovascular research (01.03.2018)
Published in Cardiovascular research (01.03.2018)
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Journal Article
Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis
Seijkens, Tom T.P., van Tiel, Claudia M., Kusters, Pascal J.H., Atzler, Dorothee, Soehnlein, Oliver, Zarzycka, Barbara, Aarts, Suzanne A.B.M., Lameijer, Marnix, Gijbels, Marion J., Beckers, Linda, den Toom, Myrthe, Slütter, Bram, Kuiper, Johan, Duchene, Johan, Aslani, Maria, Megens, Remco T.A., van ‘t Veer, Cornelis, Kooij, Gijs, Schrijver, Roy, Hoeksema, Marten A., Boon, Louis, Fay, Francois, Tang, Jun, Baxter, Samantha, Jongejan, Aldo, Moerland, Perry D., Vriend, Gert, Bleijlevens, Boris, Fisher, Edward A., Duivenvoorden, Raphael, Gerdes, Norbert, de Winther, Menno P.J., Nicolaes, Gerry A., Mulder, Willem J.M., Weber, Christian, Lutgens, Esther
Published in Journal of the American College of Cardiology (06.02.2018)
Published in Journal of the American College of Cardiology (06.02.2018)
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Journal Article
Cell-specific and divergent roles of the CD40L-CD40 axis in atherosclerotic vascular disease
Lacy, Michael, Bürger, Christina, Shami, Annelie, Ahmadsei, Maiwand, Winkels, Holger, Nitz, Katrin, van Tiel, Claudia M., Seijkens, Tom T. P., Kusters, Pascal J. H., Karshovka, Ela, Prange, Koen H. M., Wu, Yuting, Brouns, Sanne L. N., Unterlugauer, Sigrid, Kuijpers, Marijke J. E., Reiche, Myrthe E., Steffens, Sabine, Edsfeldt, Andreas, Megens, Remco T. A., Heemskerk, Johan W. M., Goncalves, Isabel, Weber, Christian, Gerdes, Norbert, Atzler, Dorothee, Lutgens, Esther
Published in Nature communications (18.06.2021)
Published in Nature communications (18.06.2021)
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Journal Article
Peritoneal Metastases From Prostate Carcinoma Treated With 177 Lu-PSMA-I&T
van Golen, Larissa W, Seijkens, Tom T P, de Feijter, Jeantine M, Vogel, Wouter
Published in Clinical nuclear medicine (01.05.2023)
Published in Clinical nuclear medicine (01.05.2023)
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Journal Article
Arterial inflammation on [18F]FDG PET/CT in melanoma patients treated with and without immune checkpoint inhibitors: CHECK-FLAME I
Polomski, Elissa A.S., Kapiteijn, Ellen W., Heemelaar, Julius C., van der Kolk, Anne V., Kalisvaart, Timo M., van de Burgt, Alina, Dibbets-Schneider, Petra, van Velden, Floris H.P., Seijkens, Tom T.P., Stöger, J. Lauran, Jukema, J. Wouter, de Geus-Oei, Lioe-Fee, Antoni, M. Louisa
Published in Atherosclerosis (01.11.2024)
Published in Atherosclerosis (01.11.2024)
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Journal Article
Immune Checkpoint Inhibitor Therapy Aggravates T Cell–Driven Plaque Inflammation in Atherosclerosis
Poels, Kikkie, van Leent, Mandy M.T., Boutros, Celine, Tissot, Hubert, Roy, Séverine, Meerwaldt, Anu E., Toner, Yohana C.A., Reiche, Myrthe E., Kusters, Pascal J.H., Malinova, Tsveta, Huveneers, Stephan, Kaufman, Audrey E., Mani, Venkatesh, Fayad, Zahi A., de Winther, Menno P.J., Marabelle, Aurelien, Mulder, Willem J.M., Robert, Caroline, Seijkens, Tom T.P., Lutgens, Esther
Published in JACC CardioOncology (01.11.2020)
Published in JACC CardioOncology (01.11.2020)
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Journal Article
Deficiency of the T cell regulator Casitas B-cell lymphoma-B aggravates atherosclerosis by inducing CD8+ T cell-mediated macrophage death
Seijkens, Tom T P, Poels, Kikkie, Meiler, Svenja, van Tiel, Claudia M, Kusters, Pascal J H, Reiche, Myrthe, Atzler, Dorothee, Winkels, Holger, Tjwa, Marc, Poelman, Hessel, Slütter, Bram, Kuiper, Johan, Gijbels, Marion, Kuivenhoven, Jan Albert, Matic, Ljubica Perisic, Paulsson-Berne, Gabrielle, Hedin, Ulf, Hansson, Göran K, Nicolaes, Gerry A F, Daemen, Mat J A P, Weber, Christian, Gerdes, Norbert, de Winther, Menno P J, Lutgens, Esther
Published in European heart journal (21.01.2019)
Published in European heart journal (21.01.2019)
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Journal Article
The emerging role for CAR T cells in solid tumor oncology
Klobuch, Sebastian, Seijkens, Tom T P, Haanen, John B A G
Published in Chinese Clinical Oncology (01.04.2023)
Published in Chinese Clinical Oncology (01.04.2023)
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Journal Article
Efficacy and safety assessment of a TRAF6-targeted nanoimmunotherapy in atherosclerotic mice and non-human primates
Lameijer, Marnix, Binderup, Tina, van Leent, Mandy M. T., Senders, Max L., Fay, Francois, Malkus, Joost, Sanchez-Gaytan, Brenda L., Teunissen, Abraham J. P., Karakatsanis, Nicolas, Robson, Philip, Zhou, Xianxiao, Ye, Yuxiang, Wojtkiewicz, Gregory, Tang, Jun, Seijkens, Tom T. P., Kroon, Jeffrey, Stroes, Erik S. G., Kjaer, Andreas, Ochando, Jordi, Reiner, Thomas, Pérez-Medina, Carlos, Calcagno, Claudia, Fisher, Edward A., Zhang, Bin, Temel, Ryan E., Swirski, Filip K., Nahrendorf, Matthias, Fayad, Zahi A., Lutgens, Esther, Mulder, Willem J. M., Duivenvoorden, Raphaël
Published in Nature biomedical engineering (01.05.2018)
Published in Nature biomedical engineering (01.05.2018)
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