Discovery and Development of Small-Molecule Inhibitors of Glycogen Synthase
Tang, Buyun, Frasinyuk, Mykhaylo S, Chikwana, Vimbai M, Mahalingan, Krishna K, Morgan, Cynthia A, Segvich, Dyann M, Bondarenko, Svitlana P, Mrug, Galyna P, Wyrebek, Przemyslaw, Watt, David S, DePaoli-Roach, Anna A, Roach, Peter J, Hurley, Thomas D
Published in Journal of medicinal chemistry (09.04.2020)
Published in Journal of medicinal chemistry (09.04.2020)
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Journal Article
Novel method for detection of glycogen in cells
Skurat, Alexander V, Segvich, Dyann M, DePaoli-Roach, Anna A, Roach, Peter J
Published in Glycobiology (Oxford) (01.05.2017)
Published in Glycobiology (Oxford) (01.05.2017)
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Journal Article
Targeting Pathogenic Lafora Bodies in Lafora Disease Using an Antibody-Enzyme Fusion
Brewer, M. Kathryn, Uittenbogaard, Annette, Austin, Grant L., Segvich, Dyann M., DePaoli-Roach, Anna, Roach, Peter J., McCarthy, John J., Simmons, Zoe R., Brandon, Jason A., Zhou, Zhengqiu, Zeller, Jill, Young, Lyndsay E.A., Sun, Ramon C., Pauly, James R., Aziz, Nadine M., Hodges, Bradley L., McKnight, Tracy R., Armstrong, Dustin D., Gentry, Matthew S.
Published in Cell metabolism (01.10.2019)
Published in Cell metabolism (01.10.2019)
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Journal Article
Metabolic and Skeletal Characterization of the KK/Ay Mouse Model—A Polygenic Mutation Model of Obese Type 2 Diabetes
Chowdhury, Nusaiba N., Surowiec, Rachel K., Kohler, Rachel K., Reul, Olivia N., Segvich, Dyann M., Wallace, Joseph M.
Published in Calcified tissue international (01.06.2024)
Published in Calcified tissue international (01.06.2024)
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Journal Article
Impaired malin expression and interaction with partner proteins in Lafora disease
Skurat, Alexander V., Segvich, Dyann M., Contreras, Christopher J., Hu, Yueh-Chiang, Hurley, Thomas D., DePaoli-Roach, Anna A., Roach, Peter J.
Published in The Journal of biological chemistry (01.05.2024)
Published in The Journal of biological chemistry (01.05.2024)
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Journal Article
Brain glycogen serves as a critical glucosamine cache required for protein glycosylation
Sun, Ramon C., Young, Lyndsay E.A., Bruntz, Ronald C., Markussen, Kia H., Zhou, Zhengqiu, Conroy, Lindsey R., Hawkinson, Tara R., Clarke, Harrison A., Stanback, Alexandra E., Macedo, Jessica K.A., Emanuelle, Shane, Brewer, M. Kathryn, Rondon, Alberto L., Mestas, Annette, Sanders, William C., Mahalingan, Krishna K., Tang, Buyun, Chikwana, Vimbai M., Segvich, Dyann M., Contreras, Christopher J., Allenger, Elizabeth J., Brainson, Christine F., Johnson, Lance A., Taylor, Richard E., Armstrong, Dustin D., Shaffer, Robert, Waechter, Charles J., Vander Kooi, Craig W., DePaoli-Roach, Anna A., Roach, Peter J., Hurley, Thomas D., Drake, Richard R., Gentry, Matthew S.
Published in Cell metabolism (06.07.2021)
Published in Cell metabolism (06.07.2021)
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Journal Article
Genetic Depletion of the Malin E3 Ubiquitin Ligase in Mice Leads to Lafora Bodies and the Accumulation of Insoluble Laforin
DePaoli-Roach, Anna A., Tagliabracci, Vincent S., Segvich, Dyann M., Meyer, Catalina M., Irimia, Jose M., Roach, Peter J.
Published in The Journal of biological chemistry (13.08.2010)
Published in The Journal of biological chemistry (13.08.2010)
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Journal Article
Glycogen Phosphomonoester Distribution in Mouse Models of the Progressive Myoclonic Epilepsy, Lafora Disease
DePaoli-Roach, Anna A., Contreras, Christopher J., Segvich, Dyann M., Heiss, Christian, Ishihara, Mayumi, Azadi, Parastoo, Roach, Peter J.
Published in The Journal of biological chemistry (09.01.2015)
Published in The Journal of biological chemistry (09.01.2015)
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Journal Article
Skeletal manifestations in a streptozotocin-induced C57BL/6 model of Type 1 diabetes
Hatch, Jennifer M., Segvich, Dyann M., Kohler, Rachel, Wallace, Joseph M.
Published in Bone Reports (01.12.2022)
Published in Bone Reports (01.12.2022)
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Journal Article
Abnormal Metabolism of Glycogen Phosphate as a Cause for Lafora Disease
Tagliabracci, Vincent S., Girard, Jean Marie, Segvich, Dyann, Meyer, Catalina, Turnbull, Julie, Zhao, Xiaochu, Minassian, Berge A., DePaoli-Roach, Anna A., Roach, Peter J.
Published in The Journal of biological chemistry (05.12.2008)
Published in The Journal of biological chemistry (05.12.2008)
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Journal Article
Muscle Glycogen Remodeling and Glycogen Phosphate Metabolism following Exhaustive Exercise of Wild Type and Laforin Knockout Mice
Irimia, Jose M., Tagliabracci, Vincent S., Meyer, Catalina M., Segvich, Dyann M., DePaoli-Roach, Anna A., Roach, Peter J.
Published in The Journal of biological chemistry (11.09.2015)
Published in The Journal of biological chemistry (11.09.2015)
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Journal Article
Incorporation of phosphate into glycogen by glycogen synthase
Contreras, Christopher J., Segvich, Dyann M., Mahalingan, Krishna, Chikwana, Vimbai M., Kirley, Terence L., Hurley, Thomas D., DePaoli-Roach, Anna A., Roach, Peter J.
Published in Archives of biochemistry and biophysics (01.05.2016)
Published in Archives of biochemistry and biophysics (01.05.2016)
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Journal Article
Laforin and malin knockout mice have normal glucose disposal and insulin sensitivity
DePaoli-Roach, Anna A., Segvich, Dyann M., Meyer, Catalina M., Rahimi, Yasmeen, Worby, Carolyn A., Gentry, Matthew S., Roach, Peter J.
Published in Human molecular genetics (01.04.2012)
Published in Human molecular genetics (01.04.2012)
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Journal Article
A prevalent variant in PPP1R3A impairs glycogen synthesis and reduces muscle glycogen content in humans and mice
Savage, David B, Zhai, Lanmin, Ravikumar, Balasubramanian, Choi, Cheol Soo, Snaar, Johanna E, McGuire, Amanda C, Wou, Sung-Eun, Medina-Gomez, Gemma, Kim, Sheene, Bock, Cheryl B, Segvich, Dyann M, Solanky, Bhavana, Deelchand, Dinesh, Vidal-Puig, Antonio, Wareham, Nicholas J, Shulman, Gerald I, Karpe, Fredrik, Taylor, Roy, Pederson, Bartholomew A, Roach, Peter J, O'Rahilly, Stephen, DePaoli-Roach, Anna A
Published in PLoS medicine (01.01.2008)
Published in PLoS medicine (01.01.2008)
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Journal Article
Correction: A Prevalent Variant in PPP1R3A Impairs Glycogen Synthesis and Reduces Muscle Glycogen Content in Humans and Mice
Savage, David B, Zhai, Lanmin, Ravikumar, Balasubramanian, Choi, Cheol Soo, Snaar, Johanna E, McGuire, Amanda C, Wou, Sung-Eun, Medina-Gomez, Gemma, Kim, Sheene, Bock, Cheryl B, Segvich, Dyann M, Solanky, Bhavana, Deelchand, Dinesh, Vidal-Puig, Antonio, Wareham, Nicholas J, Shulman, Gerald I, Karpe, Fredrik, Taylor, Roy, Pederson, Bartholomew A, Roach, Peter J, O'Rahilly, Stephen, DePaoli-Roach, Anna A
Published in PLoS medicine (01.12.2008)
Published in PLoS medicine (01.12.2008)
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Journal Article
Correction: a prevalent variant in PPP1R3A impairs glycogen synthesis and reduces muscle glycogen content in humans and mice
Savage, David B, Zhai, Lanmin, Ravikumar, Balasubramanian, Choi, Cheol Soo, Snaar, Johanna E, McGuire, Amanda C, Wou, Sung-Eun, Medina-Gomez, Gemma, Kim, Sheene, Bock, Cheryl B, Segvich, Dyann M, Solanky, Bhavana, Deelchand, Dinesh, Vidal-Puig, Antonio, Wareham, Nicholas J, Shulman, Gerald I, Karpe, Fredrik, Taylor, Roy, Pederson, Bartholomew A, Roach, Peter J, O'Rahilly, Stephen, DePaoli-Roach, Anna A
Published in PLoS medicine (01.12.2008)
Published in PLoS medicine (01.12.2008)
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Journal Article