Colocalization of GWAS and eQTL Signals Detects Target Genes
Hormozdiari, Farhad, van de Bunt, Martijn, Segrè, Ayellet V., Li, Xiao, Joo, Jong Wha J., Bilow, Michael, Sul, Jae Hoon, Sankararaman, Sriram, Pasaniuc, Bogdan, Eskin, Eleazar
Published in American journal of human genetics (01.12.2016)
Published in American journal of human genetics (01.12.2016)
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Heterothallism in Saccharomyces cerevisiae isolates from nature: effect of HO locus on the mode of reproduction
Ezov, Tal Katz, Chang, Shang-Lin, Frenkel, Ze'Ev, Segre, Ayellet V, Bahalul, Moran, Murray, Andrew W, Leu, Jun-Yi, Korol, Abraham, Kashi, Yechezkel
Published in Molecular ecology (01.01.2010)
Published in Molecular ecology (01.01.2010)
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The human transcriptome across tissues and individuals
Melé, Marta, Ferreira, Pedro G., Reverter, Ferran, DeLuca, David S., Monlong, Jean, Sammeth, Michael, Young, Taylor R., Goldmann, Jakob M, Pervouchine, Dmitri D., Sullivan, Timothy J., Johnson, Rory, Segrè, Ayellet V., Djebali, Sarah, Niarchou, Anastasia, Wright, Fred A., Lappalainen, Tuuli, Calvo, Miquel, Getz, Gad, Dermitzakis, Emmanouil T., Ardlie, Kristin G., Guigó, Roderic
Published in Science (American Association for the Advancement of Science) (08.05.2015)
Published in Science (American Association for the Advancement of Science) (08.05.2015)
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The Lin28/let-7 Axis Regulates Glucose Metabolism
Zhu, Hao, Shyh-Chang, Ng, Segrè, Ayellet V., Shinoda, Gen, Shah, Samar P., Einhorn, William S., Takeuchi, Ayumu, Engreitz, Jesse M., Hagan, John P., Kharas, Michael G., Urbach, Achia, Thornton, James E., Triboulet, Robinson, Gregory, Richard I., Altshuler, David, Daley, George Q.
Published in Cell (30.09.2011)
Published in Cell (30.09.2011)
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RNA sequence analysis reveals macroscopic somatic clonal expansion across normal tissues
Yizhak, Keren, Aguet, François, Kim, Jaegil, Hess, Julian M, Kübler, Kirsten, Grimsby, Jonna, Frazer, Ruslana, Zhang, Hailei, Haradhvala, Nicholas J, Rosebrock, Daniel, Livitz, Dimitri, Li, Xiao, Arich-Landkof, Eila, Shoresh, Noam, Stewart, Chip, Segrè, Ayellet V, Branton, Philip A, Polak, Paz, Ardlie, Kristin G, Getz, Gad
Published in Science (American Association for the Advancement of Science) (07.06.2019)
Published in Science (American Association for the Advancement of Science) (07.06.2019)
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Using an atlas of gene regulation across 44 human tissues to inform complex disease- and trait-associated variation
Gamazon, Eric R., Segrè, Ayellet V., van de Bunt, Martijn, Wen, Xiaoquan, Xi, Hualin S., Hormozdiari, Farhad, Ongen, Halit, Konkashbaev, Anuar, Derks, Eske M., Aguet, François, Quan, Jie, Nicolae, Dan L., Eskin, Eleazar, Kellis, Manolis, Getz, Gad, McCarthy, Mark I., Dermitzakis, Emmanouil T., Cox, Nancy J., Ardlie, Kristin G.
Published in Nature genetics (01.07.2018)
Published in Nature genetics (01.07.2018)
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Exploiting the GTEx resources to decipher the mechanisms at GWAS loci
Barbeira, Alvaro N, Bonazzola, Rodrigo, Gamazon, Eric R, Liang, Yanyu, Park, YoSon, Kim-Hellmuth, Sarah, Wang, Gao, Jiang, Zhuoxun, Zhou, Dan, Hormozdiari, Farhad, Liu, Boxiang, Rao, Abhiram, Hamel, Andrew R, Pividori, Milton D, Aguet, François, Bastarache, Lisa, Jordan, Daniel M, Verbanck, Marie, Do, Ron, Stephens, Matthew, Ardlie, Kristin, McCarthy, Mark, Montgomery, Stephen B, Segrè, Ayellet V, Brown, Christopher D, Lappalainen, Tuuli, Wen, Xiaoquan, Im, Hae Kyung
Published in Genome Biology (26.01.2021)
Published in Genome Biology (26.01.2021)
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Genetic analysis in UK Biobank links insulin resistance and transendothelial migration pathways to coronary artery disease
Klarin, Derek, Zhu, Qiuyu Martin, Emdin, Connor A, Chaffin, Mark, Horner, Steven, McMillan, Brian J, Leed, Alison, Weale, Michael E, Spencer, Chris C A, Aguet, François, Segrè, Ayellet V, Ardlie, Kristin G, Khera, Amit V, Kaushik, Virendar K, Natarajan, Pradeep, Kathiresan, Sekar
Published in Nature genetics (01.09.2017)
Published in Nature genetics (01.09.2017)
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Single-nucleus cross-tissue molecular reference maps toward understanding disease gene function
Eraslan, Gökcen, Drokhlyansky, Eugene, Anand, Shankara, Fiskin, Evgenij, Subramanian, Ayshwarya, Slyper, Michal, Wang, Jiali, Van Wittenberghe, Nicholas, Rouhana, John M, Waldman, Julia, Ashenberg, Orr, Lek, Monkol, Dionne, Danielle, Win, Thet Su, Cuoco, Michael S, Kuksenko, Olena, Tsankov, Alexander M, Branton, Philip A, Marshall, Jamie L, Greka, Anna, Getz, Gad, Segrè, Ayellet V, Aguet, François, Rozenblatt-Rosen, Orit, Ardlie, Kristin G, Regev, Aviv
Published in Science (American Association for the Advancement of Science) (13.05.2022)
Published in Science (American Association for the Advancement of Science) (13.05.2022)
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Deep Learning of the Retina Enables Phenome- and Genome-Wide Analyses of the Microvasculature
Zekavat, Seyedeh Maryam, Raghu, Vineet K., Trinder, Mark, Ye, Yixuan, Koyama, Satoshi, Honigberg, Michael C., Yu, Zhi, Pampana, Akhil, Urbut, Sarah, Haidermota, Sara, O’Regan, Declan P., Zhao, Hongyu, Ellinor, Patrick T., Segrè, Ayellet V., Elze, Tobias, Wiggs, Janey L., Martone, James, Adelman, Ron A., Zebardast, Nazlee, Del Priore, Lucian, Wang, Jay C., Natarajan, Pradeep
Published in Circulation (New York, N.Y.) (11.01.2022)
Published in Circulation (New York, N.Y.) (11.01.2022)
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Glaucoma-Protective Human Single-Nucleotide Polymorphism in the Angpt2 Locus Increased ANGPT2 Expression and Schlemm Canal Area in Mice-Brief Report
Kiyota, Naoki, Onay, Tuncer, Leeaw, Phoebe, Liu, Pan, Deb, Dilip K, Thomson, Benjamin R, Segrè, Ayellet V, Wiggs, Janey L, Quaggin, Susan E
Published in Arteriosclerosis, thrombosis, and vascular biology (01.10.2024)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.10.2024)
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Independent Effects of Blood Pressure on Intraocular Pressure and Retinal Ganglion Cell Degeneration: A Mendelian Randomization Study
Rajasundaram, Skanda, Segrè, Ayellet V, Gill, Dipender, Woolf, Benjamin, Zekavat, Seyedeh M, Burgess, Stephen, Khawaja, Anthony P, Zebardast, Nazlee, Wiggs, Janey L
Published in Investigative ophthalmology & visual science (19.07.2024)
Published in Investigative ophthalmology & visual science (19.07.2024)
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Machine Learning-Derived Baseline Visual Field Patterns Predict Future Glaucoma Onset in the Ocular Hypertension Treatment Study
Singh, Rishabh K, Smith, Sophie, Fingert, John, Gordon, Mae, Kass, Michael, Scheetz, Todd, Segrè, Ayellet V, Wiggs, Janey, Elze, Tobias, Zebardast, Nazlee
Published in Investigative ophthalmology & visual science (01.02.2024)
Published in Investigative ophthalmology & visual science (01.02.2024)
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TIE1 and TEK signalling, intraocular pressure, and primary open-angle glaucoma: a Mendelian randomization study
Rajasundaram, Skanda, Zebardast, Nazlee, Mehta, Puja, Khawaja, Anthony P, Warwick, Alasdair, Duchinski, Katherine, Burgess, Stephen, Gill, Dipender, Segrè, Ayellet V, Wiggs, Janey
Published in Journal of translational medicine (24.11.2023)
Published in Journal of translational medicine (24.11.2023)
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Transcriptomic analysis of the ocular posterior segment completes a cell atlas of the human eye
Monavarfeshani, Aboozar, Yan, Wenjun, Pappas, Christian, Odenigbo, Kenechukwu A, He, Zhigang, Segrè, Ayellet V, van Zyl, Tavé, Hageman, Gregory S, Sanes, Joshua R
Published in Proceedings of the National Academy of Sciences - PNAS (22.08.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (22.08.2023)
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QTL mapping of human retina DNA methylation identifies 87 gene-epigenome interactions in age-related macular degeneration
Advani, Jayshree, Mehta, Puja A., Hamel, Andrew R., Mehrotra, Sudeep, Kiel, Christina, Strunz, Tobias, Corso-Díaz, Ximena, Kwicklis, Madeline, van Asten, Freekje, Ratnapriya, Rinki, Chew, Emily Y., Hernandez, Dena G., Montezuma, Sandra R., Ferrington, Deborah A., Weber, Bernhard H. F., Segrè, Ayellet V., Swaroop, Anand
Published in Nature communications (04.03.2024)
Published in Nature communications (04.03.2024)
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Widespread Allelic Heterogeneity in Complex Traits
Hormozdiari, Farhad, Zhu, Anthony, Kichaev, Gleb, Ju, Chelsea J.-T., Segrè, Ayellet V., Joo, Jong Wha J., Won, Hyejung, Sankararaman, Sriram, Pasaniuc, Bogdan, Shifman, Sagiv, Eskin, Eleazar
Published in American journal of human genetics (04.05.2017)
Published in American journal of human genetics (04.05.2017)
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