CTGF antagonism with mAb FG-3019 enhances chemotherapy response without increasing drug delivery in murine ductal pancreas cancer
Neesse, Albrecht, Frese, Kristopher K., Bapiro, Tashinga E., Nakagawa, Tomoaki, Sternlicht, Mark D., Seeley, Todd W., Pilarsky, Christian, Jodrell, Duncan I., Spong, Suzanne M., Tuveson, David A.
Published in Proceedings of the National Academy of Sciences - PNAS (23.07.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (23.07.2013)
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Journal Article
Effects of CTGF Blockade on Attenuation and Reversal of Radiation-Induced Pulmonary Fibrosis
Bickelhaupt, Sebastian, Erbel, Christian, Timke, Carmen, Wirkner, Ute, Dadrich, Monika, Flechsig, Paul, Tietz, Alexandra, Pföhler, Johanna, Gross, Wolfgang, Peschke, Peter, Hoeltgen, Line, Katus, Hugo A, Gröne, Hermann-Josef, Nicolay, Nils H, Saffrich, Rainer, Debus, Jürgen, Sternlicht, Mark D, Seeley, Todd W, Lipson, Kenneth E, Huber, Peter E
Published in JNCI : Journal of the National Cancer Institute (01.08.2017)
Published in JNCI : Journal of the National Cancer Institute (01.08.2017)
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Journal Article
Nonclinical Characterization of the Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor Roxadustat, a Novel Treatment of Anemia of Chronic Kidney Disease
Del Balzo, Ughetta, Signore, Pierre E, Walkinshaw, Gail, Seeley, Todd W, Brenner, Mitchell C, Wang, Qingjian, Guo, Guangjie, Arend, Michael P, Flippin, Lee A, Chow, F Aisha, Gervasi, David C, Kjaergaard, Christian H, Langsetmo, Ingrid, Guenzler, Volkmar, Liu, David Y, Klaus, Steve J, Lin, Al, Neff, Thomas B
Published in The Journal of pharmacology and experimental therapeutics (01.08.2020)
Published in The Journal of pharmacology and experimental therapeutics (01.08.2020)
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Journal Article
Radiation-induced pulmonary gene expression changes are attenuated by the CTGF antibody Pamrevlumab
Sternlicht, Mark D, Wirkner, Ute, Bickelhaupt, Sebastian, Lopez Perez, Ramon, Tietz, Alexandra, Lipson, Kenneth E, Seeley, Todd W, Huber, Peter E
Published in Respiratory research (18.01.2018)
Published in Respiratory research (18.01.2018)
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Journal Article
Connective Tissue Growth Factor Inhibition Enhances Cardiac Repair and Limits Fibrosis After Myocardial Infarction
Vainio, Laura E., MD, Szabó, Zoltán, MSc, Lin, Ruizhu, MSc, Ulvila, Johanna, PhD, Yrjölä, Raisa, MSc, Alakoski, Tarja, MSc, Piuhola, Jarkko, MD, PhD, Koch, Walter J., PhD, Ruskoaho, Heikki, MD, PhD, Fouse, Shaun D., PhD, Seeley, Todd W., PhD, Gao, Erhe, MD, PhD, Signore, Pierre, PhD, Lipson, Kenneth E., PhD, Magga, Johanna, PhD, Kerkelä, Risto, MD, PhD
Published in JACC. Basic to translational science (01.02.2019)
Published in JACC. Basic to translational science (01.02.2019)
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Journal Article
Induction of erythropoiesis by hypoxia-inducible factor prolyl hydroxylase inhibitors without promotion of tumor initiation, progression, or metastasis in a VEGF-sensitive model of spontaneous breast cancer
Seeley, Todd W, Sternlicht, Mark D, Klaus, Stephen J, Neff, Thomas B, Liu, David Y
Published in Hypoxia (01.01.2017)
Published in Hypoxia (01.01.2017)
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Journal Article
Cooperative interaction of CTGF and TGF-β in animal models of fibrotic disease
Wang, Qingjian, Usinger, William, Nichols, Blake, Gray, Julia, Xu, Leon, Seeley, Todd W, Brenner, Mitch, Guo, Guangjie, Zhang, Weihua, Oliver, Noelynn, Lin, Al, Yeowell, David
Published in Fibrogenesis & tissue repair (01.02.2011)
Published in Fibrogenesis & tissue repair (01.02.2011)
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Journal Article
Connective tissue growth factor regulates cardiac function and tissue remodeling in a mouse model of dilated cardiomyopathy
Koshman, Yevgeniya E, Sternlicht, Mark D, Kim, Taehoon, O'Hara, Christopher P, Koczor, Christopher A, Lewis, William, Seeley, Todd W, Lipson, Kenneth E, Samarel, Allen M
Published in Journal of molecular and cellular cardiology (01.12.2015)
Published in Journal of molecular and cellular cardiology (01.12.2015)
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Journal Article
Prognostic utility of inflammation biomarkers in a PDAC trial involving the human anti-CTGF antibody pamrevlumab
Sternlicht, Mark D., Li, Dongxia, Nguyen, Viet-Tam, Carney, Mairead, Zhou, Duo, Lipson, Kenneth E., Kouchakji, Elias, Picozzi, Vincent J., Carrier, Ewa, Seeley, Todd W.
Published in Journal of clinical oncology (01.02.2020)
Published in Journal of clinical oncology (01.02.2020)
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Journal Article
Cooperative interaction of CTGF and TGF-[beta] in animal models of fibrotic disease
Wang, Qingjian, Usinger, William, Nichols, Blake, Gray, Julia, Xu, Leon, Seeley, Todd W, Brenner, Mitch, Guo, Guangjie, Zhang, Weihua, Oliver, Noelynn, Lin, Al, Yeowell, David
Published in Fibrogenesis & tissue repair (01.02.2011)
Published in Fibrogenesis & tissue repair (01.02.2011)
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Journal Article
Phosphorylation of human MAD1 by the BUB1 kinase in vitro
Seeley, T W, Wang, L, Zhen, J Y
Published in Biochemical and biophysical research communications (13.04.1999)
Published in Biochemical and biophysical research communications (13.04.1999)
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Journal Article
ENHANCED ERYTHROPOIESIS AND IRON METABOLISM
KLAUS, Stephen J, NEFF, Thomas B, MOLINEAUX, Christopher J, LANGSETMO PAROBOK, Ingrid, STEPHENSON, Robert C, SEELEY, Todd W, GUENZLER-PUKALL, Volkmar
Year of Publication 06.06.2024
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Year of Publication 06.06.2024
Patent
Enhanced erythropoiesis and iron metabolism
Klaus, Stephen J, Guenzler-Pukall, Volkmar, Seeley, Todd W, Stephenson, Robert C, Neff, Thomas B, Molineaux, Christopher J, Langsetmo Parobok, Ingrid
Year of Publication 20.06.2023
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Year of Publication 20.06.2023
Patent
Phosphorylation of Human MAD1 by the BUB1 Kinasein Vitro
Seeley, Todd W., Wang, Ling, Zhen, Julia Y.
Published in Biochemical and biophysical research communications (13.04.1999)
Published in Biochemical and biophysical research communications (13.04.1999)
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Journal Article
ENHANCED ERYTHROPOIESIS AND IRON METABOLISM
Klaus, Stephen J, Guenzler-Pukall, Volkmar, Seeley, Todd W, Stephenson, Robert C, Neff, Thomas B, Molineaux, Christopher J, Langsetmo Parobok, Ingrid
Year of Publication 22.04.2021
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Year of Publication 22.04.2021
Patent
Enhanced erythropoiesis and iron metabolism
Klaus, Stephen J, Guenzler-Pukall, Volkmar, Seeley, Todd W, Stephenson, Robert C, Neff, Thomas B, Molineaux, Christopher J, Langsetmo Parobok, Ingrid
Year of Publication 19.01.2021
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Year of Publication 19.01.2021
Patent
Enhanced erythropoiesis and iron metabolism
Klaus, Stephen J, Guenzler-Pukall, Volkmar, Seeley, Todd W, Stephenson, Robert C, Neff, Thomas B, Molineaux, Christopher J, Langsetmo Parobok, Ingrid
Year of Publication 05.01.2021
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Year of Publication 05.01.2021
Patent