Chanzyme TRPM7 Mediates the Ca2+ Influx Essential for Lipopolysaccharide-Induced Toll-Like Receptor 4 Endocytosis and Macrophage Activation
Schappe, Michael S., Szteyn, Kalina, Stremska, Marta E., Mendu, Suresh K., Downs, Taylor K., Seegren, Philip V., Mahoney, Michelle A., Dixit, Sumeet, Krupa, Julia K., Stipes, Eric J., Rogers, Jason S., Adamson, Samantha E., Leitinger, Norbert, Desai, Bimal N.
Published in Immunity (Cambridge, Mass.) (16.01.2018)
Published in Immunity (Cambridge, Mass.) (16.01.2018)
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Neuronal hyperexcitability is a DLK-dependent trigger of herpes simplex virus reactivation that can be induced by IL-1
Cuddy, Sean R, Schinlever, Austin R, Dochnal, Sara, Seegren, Philip V, Suzich, Jon, Kundu, Parijat, Downs, Taylor K, Farah, Mina, Desai, Bimal N, Boutell, Chris, Cliffe, Anna R
Published in eLife (22.12.2020)
Published in eLife (22.12.2020)
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Efferocytosis requires periphagosomal Ca2+-signaling and TRPM7-mediated electrical activity
Schappe, Michael S., Stremska, Marta E., Busey, Gregory W., Downs, Taylor K., Seegren, Philip V., Mendu, Suresh K., Flegal, Zachary, Doyle, Catherine A., Stipes, Eric J., Desai, Bimal N.
Published in Nature communications (09.06.2022)
Published in Nature communications (09.06.2022)
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Analogs of FTY720 inhibit TRPM7 but not S1PRs and exert multimodal anti-inflammatory effects
Busey, Gregory W, Manjegowda, Mohan C, Huang, Tao, Iobst, Wesley H, Naphade, Shardul S, Kennedy, Joel A, Doyle, Catherine A, Seegren, Philip V, Lynch, Kevin R, Desai, Bimal N
Published in The Journal of general physiology (01.01.2024)
Published in The Journal of general physiology (01.01.2024)
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Mitochondrial Ca2+ Signaling Is an Electrometabolic Switch to Fuel Phagosome Killing
Seegren, Philip V., Downs, Taylor K., Stremska, Marta E., Harper, Logan R., Cao, Ruofan, Olson, Rachel J., Upchurch, Clint M., Doyle, Catherine A., Kennedy, Joel, Stipes, Eric L., Leitinger, Norbert, Periasamy, Ammasi, Desai, Bimal N.
Published in Cell reports (Cambridge) (24.11.2020)
Published in Cell reports (Cambridge) (24.11.2020)
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Reduced mitochondrial calcium uptake in macrophages is a major driver of inflammaging
Seegren, Philip V, Harper, Logan R, Downs, Taylor K, Zhao, Xiao-Yu, Viswanathan, Shivapriya B, Stremska, Marta E, Olson, Rachel J, Kennedy, Joel, Ewald, Sarah E, Kumar, Pankaj, Desai, Bimal N
Published in Nature aging (01.07.2023)
Published in Nature aging (01.07.2023)
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Macrophage acetyl-CoA carboxylase regulates acute inflammation through control of glucose and lipid metabolism
Yeudall, Scott, Upchurch, Clint M, Seegren, Philip V, Pavelec, Caitlin M, Greulich, Jan, Lemke, Michael C, Harris, Thurl E, Desai, Bimal N, Hoehn, Kyle L, Leitinger, Norbert
Published in Science advances (25.11.2022)
Published in Science advances (25.11.2022)
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Journal Article
Chanzyme TRPM7 Mediates the Ca 2+ Influx Essential for Lipopolysaccharide-Induced Toll-Like Receptor 4 Endocytosis and Macrophage Activation
Schappe, Michael S, Szteyn, Kalina, Stremska, Marta E, Mendu, Suresh K, Downs, Taylor K, Seegren, Philip V, Mahoney, Michelle A, Dixit, Sumeet, Krupa, Julia K, Stipes, Eric J, Rogers, Jason S, Adamson, Samantha E, Leitinger, Norbert, Desai, Bimal N
Published in Immunity (Cambridge, Mass.) (16.01.2018)
Published in Immunity (Cambridge, Mass.) (16.01.2018)
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Journal Article
Efferocytosis requires periphagosomal Ca 2+ -signaling and TRPM7-mediated electrical activity
Schappe, Michael S, Stremska, Marta E, Busey, Gregory W, Downs, Taylor K, Seegren, Philip V, Mendu, Suresh K, Flegal, Zachary, Doyle, Catherine A, Stipes, Eric J, Desai, Bimal N
Published in Nature communications (09.06.2022)
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Published in Nature communications (09.06.2022)
Journal Article
Mitochondrial Ca 2+ Signaling Is an Electrometabolic Switch to Fuel Phagosome Killing
Seegren, Philip V, Downs, Taylor K, Stremska, Marta E, Harper, Logan R, Cao, Ruofan, Olson, Rachel J, Upchurch, Clint M, Doyle, Catherine A, Kennedy, Joel, Stipes, Eric L, Leitinger, Norbert, Periasamy, Ammasi, Desai, Bimal N
Published in Cell reports (Cambridge) (24.11.2020)
Get full text
Published in Cell reports (Cambridge) (24.11.2020)
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