Preferential transcription of the mutated allele in NPM1 mutated acute myeloid leukaemia
Bailey, G. D., Doolan, L., Baskar, A., Smith, L. C., Seedhouse, C. H.
Published in Scientific reports (19.10.2020)
Published in Scientific reports (19.10.2020)
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DNA repair contributes to the drug-resistant phenotype of primary acute myeloid leukaemia cells with FLT3 internal tandem duplications and is reversed by the FLT3 inhibitor PKC412
SEEDHOUSE, C. H, HUNTER, H. M, LLOYD-LEWIS, B, MASSIP, A-M, PALLIS, M, CARTER, Gl, GRUNDY, M, SHANG, S, RUSSELL, N. H
Published in Leukemia (01.12.2006)
Published in Leukemia (01.12.2006)
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Journal Article
Caspase-8 polymorphisms result in reduced Alemtuzumab-induced T-cell apoptosis and worse survival after transplantation
Shaw, B E, Lee, F, Krishnamurthy, S, Byrne, J L, Seedhouse, C, Mayor, N P, Maldonado-Torres, H, Saudemont, A, Marsh, S G E, Madrigal, J A, Russell, N H
Published in Bone marrow transplantation (Basingstoke) (01.02.2015)
Published in Bone marrow transplantation (Basingstoke) (01.02.2015)
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275 Targeting XRCC1 (X-ray Repair Cross-complementing Gene 1), a Key DNA Base Excision Repair Protein for Personalized Therapy in Breast and Ovarian Cancer
Sultana, R, Abdel-Fatah, T, Albarakati, N, Abbotts, R, Seedhouse, C, Ball, G, Chan, S, Rakha, E, Ellis, I, Madhusudan, S
Published in European journal of cancer (1990) (01.11.2012)
Published in European journal of cancer (1990) (01.11.2012)
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PO-014 Targeting PARP1 in XRCC1 deficient sporadic invasive breast cancer or pre-invasive ductal carcinoma in situ for synthetic lethality and chemoprevention
Ali, R, Al-kawaz, A, Toss, MS, Green, A, Miligy, IA, Mesquita, K Almeida, Seedhouse, C, Mirza, S, Rakha, E, Madhusudan, S
Published in ESMO open (01.07.2018)
Published in ESMO open (01.07.2018)
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The genotype distribution of the XRCC1 gene indicates a role for base excision repair in the development of therapy-related acute myeloblastic leukemia
SEEDHOUSE, Claire, BAINTON, Rowena, LEWIS, Michael, HARDING, Alexander, RUSSELL, Nigel, DAS-GUPTA, Emma
Published in Blood (15.11.2002)
Published in Blood (15.11.2002)
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PB2102 A SAME DAY ASSAY USING CYTOCHROME C RELEASE DETERMINES SENSITIVITY TO COOPERATIVE BCL‐2 AND MCL‐1 TARGETING IN MULTIPLE MYELOMA CELL LINES AND PRIMARY SAMPLES
Grundy, M., Cull, J., Al‐Kaisi, F., Williams, C., Smith, D., Seedhouse, C.
Published in HemaSphere (01.06.2019)
Published in HemaSphere (01.06.2019)
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The Effect of ABC Transporters and FLT3 Status on the Activity of the Aurora Kinase B Inhibitor AZD1152 in AML Cells
Grundy, Martin, Shang, Shili, Seedhouse, C., Russell, Nigel H., Pallis, Monica
Published in Blood (16.11.2008)
Published in Blood (16.11.2008)
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Journal Article
A caspase8 promoter polymorphism is associated with increased TRM and reduced survival following T-cell depleted unrelated donor transplantation using alemtuzumab
Krishnamurthy, S, Shaw, B.E, Byrne, J, Seedhouse, C, Mayor, N, Madrigal, J.A, Russell, N
Published in Bone marrow transplantation (Basingstoke) (01.03.2009)
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Published in Bone marrow transplantation (Basingstoke) (01.03.2009)
Journal Article
The Effect of the CASP8 -6526N Del Promoter Polymorphism on Outcome in T-Cell Depleted Unrelated Donor Haemopoetic Stem Cell Transplants (HSCT)
Krishnamurthy, Suchitra, Shaw, Bronwen E., Byrne, J. L, Seedhouse, C., Mayor, Neema P, Madrigal, A. J, Russell, Nigel H.
Published in Blood (16.11.2008)
Published in Blood (16.11.2008)
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Journal Article
A Polymorphism Study on Detoxification and DNA Repair Genes in 700 MDS Patients Demonstrates An Association Between Genotype and An Aberrant Karyotype
Seedhouse, C., Fischer, Stephanie, Ganster, Christina, Fonatsch, Christa, Valent, Peter, Germing, Ulrich, Russell, Nigel H., Haase, Detlef
Published in Blood (16.11.2008)
Published in Blood (16.11.2008)
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