Implications for reactive oxygen species in schizophrenia pathogenesis
Koga, Minori, Serritella, Anthony V, Sawa, Akira, Sedlak, Thomas W
Published in Schizophrenia research (01.09.2016)
Published in Schizophrenia research (01.09.2016)
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Journal Article
The diverse functions of GAPDH: Views from different subcellular compartments
Tristan, Carlos, Shahani, Neelam, Sedlak, Thomas W., Sawa, Akira
Published in Cellular signalling (01.02.2011)
Published in Cellular signalling (01.02.2011)
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Journal Article
The glutathione cycle shapes synaptic glutamate activity
Sedlak, Thomas W., Paul, Bindu D., Parker, Gregory M., Hester, Lynda D., Snowman, Adele M., Taniguchi, Yu, Kamiya, Atsushi, Snyder, Solomon H., Sawa, Akira
Published in Proceedings of the National Academy of Sciences - PNAS (12.02.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (12.02.2019)
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Journal Article
Bilirubin and glutathione have complementary antioxidant and cytoprotective roles
Sedlak, Thomas W, Saleh, Masoumeh, Higginson, Daniel S, Paul, Bindu D, Juluri, Krishna R, Snyder, Solomon H
Published in Proceedings of the National Academy of Sciences - PNAS (31.03.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (31.03.2009)
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A multimodal approach to studying the relationship between peripheral glutathione, brain glutamate, and cognition in health and in schizophrenia
Coughlin, Jennifer M., Yang, Kun, Marsman, Anouk, Pradhan, Subechhya, Wang, Min, Ward, Rebecca E., Bonekamp, Susanne, Ambinder, Emily B., Higgs, Cecilia P., Kim, Pearl K., Edwards, Jamie A., Varvaris, Mark, Wang, Hongxing, Posporelis, Sotirios, Ma, Shuangchao, Tsujimura, Tsuyoshi, Edden, Richard A. E., Pomper, Martin G., Sedlak, Thomas W., Fournier, Margot, Schretlen, David J., Cascella, Nicola G., Barker, Peter B., Sawa, Akira
Published in Molecular psychiatry (01.07.2021)
Published in Molecular psychiatry (01.07.2021)
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Journal Article
Cognitive and motivational deficits together with prefrontal oxidative stress in a mouse model for neuropsychiatric illness
Johnson, Alexander W., Jaaro-Peled, Hanna, Shahani, Neelam, Sedlak, Thomas W., Zoubovsky, Sandra, Burruss, Daniel, Emiliani, Francesco, Sawa, Akira, Gallagher, Michela
Published in Proceedings of the National Academy of Sciences - PNAS (23.07.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (23.07.2013)
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Paliperidone induced neutropenia in first episode psychosis: a case report
Martos, Natalie, Hall, William, Marhefka, Alicia, Sedlak, Thomas W, Nucifora, Jr, Frederick C
Published in BMC psychiatry (06.02.2021)
Published in BMC psychiatry (06.02.2021)
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Journal Article
Behavioral Effects of Cocaine Mediated by Nitric Oxide-GAPDH Transcriptional Signaling
Xu, Risheng, Serritella, Anthony V., Sen, Tanusree, Farook, Justin M., Sedlak, Thomas W., Baraban, Jay, Snyder, Solomon H., Sen, Nilkantha
Published in Neuron (Cambridge, Mass.) (22.05.2013)
Published in Neuron (Cambridge, Mass.) (22.05.2013)
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Journal Article
Constituents of bile, bilirubin and TUDCA, protect against oxidative stress-induced retinal degeneration
Oveson, Brian C, Iwase, Takeshi, Hackett, Sean F, Lee, Sun Young, Usui, Shinichi, Sedlak, Thomas W, Snyder, Solomon H, Campochiaro, Peter A, Sung, Jennifer U
Published in Journal of neurochemistry (01.01.2011)
Published in Journal of neurochemistry (01.01.2011)
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Journal Article
Sex-specific involvement of the Notch–JAG pathway in social recognition
Jaaro-Peled, Hanna, Landek-Salgado, Melissa A., Cascella, Nicola G., Nucifora, Frederick C., Coughlin, Jennifer M., Nestadt, Gerald, Sedlak, Thomas W., Lavoie, Joelle, De Silva, Sarah, Lee, Somin, Tajinda, Katsunori, Hiyama, Hideki, Ishizuka, Koko, Yang, Kun, Sawa, Akira
Published in Translational psychiatry (10.03.2022)
Published in Translational psychiatry (10.03.2022)
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Journal Article
Role of Apoptosis Signal-regulating Kinase 1 (ASK1) as an Activator of the GAPDH-Siah1 Stress-Signaling Cascade
Tristan, Carlos A., Ramos, Adriana, Shahani, Neelam, Emiliani, Francesco E., Nakajima, Hidemitsu, Noeh, Christopher C., Kato, Yoshinori, Takeuchi, Tadayoshi, Noguchi, Takuya, Kadowaki, Hisae, Sedlak, Thomas W., Ishizuka, Koko, Ichijo, Hidenori, Sawa, Akira
Published in The Journal of biological chemistry (02.01.2015)
Published in The Journal of biological chemistry (02.01.2015)
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Hydrogen sulfide is neuroprotective in Alzheimer’s disease by sulfhydrating GSK3β and inhibiting Tau hyperphosphorylation
Giovinazzo, Daniel, Bursac, Biljana, Sbodio, Juan I., Nalluru, Sumedha, Vignane, Thibaut, Snowman, Adele M., Albacarys, Lauren M., Sedlak, Thomas W., Torregrossa, Roberta, Whiteman, Matthew, Filipovic, Milos R., Snyder, Solomon H., Paul, Bindu D.
Published in Proceedings of the National Academy of Sciences - PNAS (26.01.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (26.01.2021)
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Journal Article
Oxidative stress and schizophrenia: recent breakthroughs from an old story
Emiliani, Francesco E, Sedlak, Thomas W, Sawa, Akira
Published in Current opinion in psychiatry (01.05.2014)
Published in Current opinion in psychiatry (01.05.2014)
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Journal Article
Heme Oxygenase-2 Is Activated by Calcium-Calmodulin
Boehning, Darren, Sedaghat, Leela, Sedlak, Thomas W, Snyder, Solomon H
Published in The Journal of biological chemistry (23.07.2004)
Published in The Journal of biological chemistry (23.07.2004)
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Journal Article
Assessing Brain Metabolism With 7-T Proton Magnetic Resonance Spectroscopy in Patients With First-Episode Psychosis
Wang, Anna M, Pradhan, Subechhya, Coughlin, Jennifer M, Trivedi, Aditi, DuBois, Samantha L, Crawford, Jeffrey L, Sedlak, Thomas W, Nucifora, Jr, Fredrick C, Nestadt, Gerald, Nucifora, Leslie G, Schretlen, David J, Sawa, Akira, Barker, Peter B
Published in JAMA psychiatry (Chicago, Ill.) (01.03.2019)
Published in JAMA psychiatry (Chicago, Ill.) (01.03.2019)
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Journal Article
Behavioral Effects of Cocaine Mediated by Nitric Oxide-GAPDH Transcriptional Signaling
Xu, Risheng, Serritella, Anthony V., Sen, Tanusree, Farook, Justin M., Sedlak, Thomas W., Baraban, Jay, Snyder, Solomon H., Sen, Nilkantha
Published in Neuron (Cambridge, Mass.) (10.07.2013)
Published in Neuron (Cambridge, Mass.) (10.07.2013)
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Journal Article
Bilirubin Links Heme Metabolism to Neuroprotection by Scavenging Superoxide
Vasavda, Chirag, Kothari, Ruchita, Malla, Adarsha P, Tokhunts, Robert, Lin, Anthony, Ji, Ming, Ricco, Cristina, Xu, Risheng, Saavedra, Harry G, Sbodio, Juan I, Snowman, Adele M, Albacarys, Lauren, Hester, Lynda, Sedlak, Thomas W, Paul, Bindu D, Snyder, Solomon H
Published in Cell chemical biology (17.10.2019)
Published in Cell chemical biology (17.10.2019)
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Journal Article
Sulforaphane Augments Glutathione and Influences Brain Metabolites in Human Subjects: A Clinical Pilot Study
Sedlak, Thomas W, Nucifora, Leslie G, Koga, Minori, Shaffer, Lindsay S, Higgs, Cecilia, Tanaka, Teppei, Wang, Anna M, Coughlin, Jennifer M, Barker, Peter B, Fahey, Jed W, Sawa, Akira
Published in Molecular neuropsychiatry (01.05.2018)
Published in Molecular neuropsychiatry (01.05.2018)
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