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Antibiotics, Sedatives, and Catecholamines Further Compromise Sepsis-Induced Immune Suppression in Peripheral Blood Mononuclear Cells
Miller, Muska, Melis, Miranda J, Miller, James R C, Kleyman, Anna, Shankar-Hari, Manu, Singer, Mervyn
Published in Critical care medicine (01.04.2024)
Published in Critical care medicine (01.04.2024)
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Pharmacokinetics and pharmacodynamics of γ‐hydroxybutyrate in healthy subjects
Liechti, Matthias E., Quednow, Boris B., Liakoni, Evangelia, Dornbierer, Dario, Rotz, Robin, Gachet, Maria Salomé, Gertsch, Jürg, Seifritz, Erich, Bosch, Oliver G.
Published in British journal of clinical pharmacology (01.05.2016)
Published in British journal of clinical pharmacology (01.05.2016)
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Pharmacokinetic pharmacodynamic modeling of analgesics and sedatives in children
Bardol, Maddlie, Pan, Shan, Walker, Suellen M., Standing, Joseph F., Dawes, Joy M.
Published in Pediatric anesthesia (01.10.2023)
Published in Pediatric anesthesia (01.10.2023)
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Safety, Pharmacokinetics, and Pharmacodynamics of Midazolam Gel After Rectal Administration in Healthy Chinese Subjects
Zhou, Sufeng, Zhu, Jinying, Sun, Xiaodi, Xie, Lijun, Zhao, Yuqing, Ding, Sijia, Wang, Lu, Chen, Juan, Zhu, Bei, Zheng, Aiping, Li, Yajuan, Zhou, Chen, Shao, Feng
Published in Clinical drug investigation (01.06.2023)
Published in Clinical drug investigation (01.06.2023)
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Pharmacokinetic-pharmacodynamic Modelling of NH600001 in Healthy Subjects and Patients Undergoing Gastroscopy
Liu, Yaxin, Kuang, Yun, Huang, Jie, Jiang, Dan, Cao, Yajie, Gao, Qi, Li, Zifeng, Ouyang, Wen, Wang, Saiying, Pei, Qi, Yang, Guoping
Published in The AAPS journal (21.12.2024)
Published in The AAPS journal (21.12.2024)
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Mechanism-based population pharmacokinetic and pharmacodynamic modeling of intravenous and intranasal dexmedetomidine in healthy subjects
Yoo, Heedoo, Iirola, Timo, Vilo, Sanna, Manner, Tuula, Aantaa, Riku, Lahtinen, Maria, Scheinin, Mika, Olkkola, Klaus T., Jusko, William J.
Published in European journal of clinical pharmacology (01.10.2015)
Published in European journal of clinical pharmacology (01.10.2015)
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Propranolol As an Anxiolytic to Reduce the Use of Sedatives for Critically Ill Adults Receiving Mechanical Ventilation (PROACTIVE): An Open-Label Randomized Controlled Trial
Downar, James, Lapenskie, Julie, Kanji, Salmaan, Watpool, Irene, Haines, Jessica, Saeed, Uzma, Porteous, Rebecca, Polskaia, Nadia, Burry, Lisa, Himed, Shuhira, Anderson, Koby, Fox-Robichaud, Alison
Published in Critical care medicine (01.02.2025)
Published in Critical care medicine (01.02.2025)
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A Placebo- and Midazolam-Controlled Phase I Single Ascending-Dose Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics of Remimazolam (CNS 7056): Part I. Safety, Efficacy, and Basic Pharmacokinetics
Antonik, Laurie J., Goldwater, D. Ronald, Kilpatrick, Gavin J., Tilbrook, Gary S., Borkett, Keith M.
Published in Anesthesia and analgesia (01.08.2012)
Published in Anesthesia and analgesia (01.08.2012)
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Concurrent Use of Alcohol and Sedatives Among Persons Prescribed Chronic Opioid Therapy: Prevalence and Risk Factors
Saunders, Kathleen W, Von Korff, Michael, Campbell, Cynthia I, Banta-Green, Caleb J, Sullivan, Mark D, Merrill, Joseph O, Weisner, Constance
Published in The journal of pain (01.03.2012)
Published in The journal of pain (01.03.2012)
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Comparison of safety and efficacy of commonly used sedatives in bronchoscopy examination: a Bayesian network meta-analysis of randomized controlled trials
Chen, Weiying, Chen, Feng, Luo, Xiaodan, Li, Dongmei, Li, Hong, Bai, Fuhai
Published in Minerva anestesiologica (01.05.2025)
Published in Minerva anestesiologica (01.05.2025)
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A Phase 1, Single-center, Double-blind, Placebo-controlled Study in Healthy Subjects to Assess the Safety, Tolerability, Clinical Effects, and Pharmacokinetics–Pharmacodynamics of Intravenous Cyclopropyl-methoxycarbonylmetomidate (ABP-700) after a Single Ascending Bolus Dose
Struys, Michel M. R. F., Valk, Beatrijs I., Eleveld, Douglas J., Absalom, Anthony R., Meyer, Peter, Meier, Sascha, den Daas, Izaak, Chou, Thomas, van Amsterdam, Kai, Campagna, Jason A., Sweeney, Steven P.
Published in Anesthesiology (Philadelphia) (01.07.2017)
Published in Anesthesiology (Philadelphia) (01.07.2017)
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Efficacy and safety of Wuling capsule, a single herbal formula, in Chinese subjects with insomnia: A multicenter, randomized, double-blind, placebo-controlled trial
Lin, Yan, Wang, Xiao-yun, Ye, Ren, Hu, Wan-hua, Sun, Shu-chen, Jiao, Hong-juan, Song, Xiu-hua, Yuan, Zheng-zhong, Zheng, Yuan-yuan, Zheng, Guo-qing, He, Jin-Cai
Published in Journal of ethnopharmacology (09.01.2013)
Published in Journal of ethnopharmacology (09.01.2013)
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Sedation Effects Produced by a Ciprofol Initial Infusion or Bolus Dose Followed by Continuous Maintenance Infusion in Healthy Subjects: A Phase 1 Trial
Hu, Chao, Ou, Xiaofeng, Teng, Yi, Shu, Shiqing, Wang, Ying, Zhu, Xiaohong, Kang, Yan, Miao, Jia
Published in Advances in therapy (01.11.2021)
Published in Advances in therapy (01.11.2021)
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Effects of Passiflora incarnata Linnaeus on polysomnographic sleep parameters in subjects with insomnia disorder: a double-blind randomized placebo-controlled study
Lee, Jeewon, Jung, Han-Young, Lee, Soyoung Irene, Choi, Ji Ho, Kim, Shin-Gyeom
Published in International clinical psychopharmacology (01.01.2020)
Published in International clinical psychopharmacology (01.01.2020)
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Fractures in users of antidepressants and anxiolytics and sedatives: effects of age and dose
Vestergaard, P., Prieto-Alhambra, D., Javaid, M. K., Cooper, C.
Published in Osteoporosis international (01.02.2013)
Published in Osteoporosis international (01.02.2013)
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Gender differences in pharmacokinetics and pharmacodynamics of zolpidem following sublingual administration
Greenblatt, David J, Harmatz, Jerold S, Singh, Nikhilesh N, Steinberg, Frank, Roth, Thomas, Moline, Margaret L, Harris, Stephen C, Kapil, Ram P
Published in Journal of clinical pharmacology (01.03.2014)
Published in Journal of clinical pharmacology (01.03.2014)
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