Antitumor activity of 2-fluoro-2'-deoxyadenosine against tumors that express Escherichia coli purine nucleoside phosphorylase
Parker, William B, Allan, Paula W, Hassan, Abdalla E A, Secrist, 3rd, John A, Sorscher, Eric J, Waud, William R
Published in Cancer gene therapy (01.01.2003)
Published in Cancer gene therapy (01.01.2003)
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Antibiotic-mediated chemoprotection enhances adaptation of E. coli PNP for herpes simplex virus-based glioma therapy
Bharara, Suman, Sorscher, Eric J, Gillespie, G Yancey, Lindsey, J Russell, Hong, Jeong S, Curlee, Kimberly V, Allan, Paula W, Gadi, V K, Alexander, Sherrie A, Secrist, 3rd, John A, Parker, William B, Waud, William R
Published in Human gene therapy (01.03.2005)
Published in Human gene therapy (01.03.2005)
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Enhancement of Nucleoside Cytotoxicity through Nucleotide Prodrugs
Rose, Jerry D, Parker, William B, Someya, Hitoshi, Shaddix, Sue C, Montgomery, John A, Secrist, John A
Published in Journal of medicinal chemistry (26.09.2002)
Published in Journal of medicinal chemistry (26.09.2002)
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Journal Article
In vivo gene therapy of cancer with E. coli purine nucleoside phosphorylase
Parker, W B, King, S A, Allan, P W, Bennett, Jr, L L, Secrist, 3rd, J A, Montgomery, J A, Gilbert, K S, Waud, W R, Wells, A H, Gillespie, G Y, Sorscher, E J
Published in Human gene therapy (20.09.1997)
Published in Human gene therapy (20.09.1997)
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Structure-based design of inhibitors of purine nucleoside phosphorylase. 1. 9-(Arylmethyl) derivatives of 9-deazaguanine
Montgomery, John A., Niwas, Shri, Rose, Jerry D., Secrist, John A., Babu, Y. Sudhakar, Bugg, Charles E., Erion, Mark D., Guida, Wayne C., Ealick, Steven E.
Published in Journal of medicinal chemistry (1993)
Published in Journal of medicinal chemistry (1993)
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Effects of 2-chloro-9-(3-deoxy-2-fluoro-β-D-arabinofuranosyl)adenine on K562 cellular metabolism and the inhibition of human ribonucleotide reductase and DNA polymerases by its 5'-triphosphate
PARKER, W. B, SHADDIX, S. C, CHI-HSIUNG CHANG, WHITE, E. L, ROSE, L. M, BROCKMAN, R. W, SHORTNACY, A. T, MONTGOMERY, J. A, SECRIST, J. A, LEE BENNETT, L. JR
Published in Cancer research (Chicago, Ill.) (01.05.1991)
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Published in Cancer research (Chicago, Ill.) (01.05.1991)
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Synthesis and Biological Activity of Certain 4‘-Thio-d-arabinofuranosylpurine Nucleosides
Secrist, John A, Tiwari, Kamal N, Shortnacy-Fowler, Anita T, Messini, Lea, Riordan, James M, Montgomery, John A, Meyers, Scott C, Ealick, Steven E
Published in Journal of medicinal chemistry (24.09.1998)
Published in Journal of medicinal chemistry (24.09.1998)
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Structure-based design of inhibitors of purine nucleoside phosphorylase. 3. 9-Arylmethyl derivatives of 9-deazaguanine substituted on the methylene group
Erion, M D, Niwas, S, Rose, J D, Ananthan, S, Allen, M, Secrist, 3rd, J A, Babu, Y S, Bugg, C E, Guida, W C, Ealick, S E
Published in Journal of medicinal chemistry (26.11.1993)
Published in Journal of medicinal chemistry (26.11.1993)
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Multi-log cytotoxicity of carbocyclic 2'-deoxyguanosine in HSV-TK-expressing human tumor cells
Shewach, Donna S, Murphy, Patrick J, Robinson, Blaine W, Vuletich, Jennifer, Boucher, Paul D, Blobaum, Anna L, Zerbe, Laura, Secrist, 3rd, John A, Parker, William B
Published in Human gene therapy (01.03.2002)
Published in Human gene therapy (01.03.2002)
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Comparison of the effect of Carbovir, AZT, and dideoxynucleoside triphosphates on the activity of human immunodeficiency virus reverse transcriptase and selected human polymerases
White, E.Lucile, Parker, William B., Macy, Lisa J., Shaddix, Sue C., McCaleb, George, Secrist, John A., Vince, Robert, Shannon, William M.
Published in Biochemical and biophysical research communications (15.06.1989)
Published in Biochemical and biophysical research communications (15.06.1989)
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5,5-Disubstituted hydantoins: syntheses and anti-HIV activity
Comber, Robert N, Reynolds, Robert C, Friedrich, Joyce D, Manguikian, Roupen A, Buckheit, Robert W, Truss, Jackie W, Shannon, William M, Secrist, John A
Published in Journal of medicinal chemistry (01.09.1992)
Published in Journal of medicinal chemistry (01.09.1992)
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Structure-Based Design of Inhibitors of Purine Nucleoside Phosphorylase. 4. A Study of Phosphate Mimics
Guida, Wayne C, Elliott, Robert D, Thomas, H. Jeanette, Secrist, John A, Babu, Y. Sudhakar, Bugg, Charles E, Erion, Mark D, Ealick, Steven E, Montgomery, John A
Published in Journal of medicinal chemistry (01.04.1994)
Published in Journal of medicinal chemistry (01.04.1994)
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Journal Article
Phosphonate Analogs of Carbocyclic Nucleotides
Elliott, Robert D, Rener, Gregory A, Riordan, James M, Secrist, John A, Bennett, L. Lee, Parker, William B, Montgomery, John A
Published in Journal of medicinal chemistry (01.03.1994)
Published in Journal of medicinal chemistry (01.03.1994)
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Journal Article
Incorporation of the carbocyclic analog of 2'-deoxyguanosine into the DNA of herpes simplex virus and of HEp-2 cells infected with herpes simplex virus
W B Parker, S C Shaddix, P W Allan, G Arnett, L M Rose, W M Shannon, Y F Shealy, J A Montgomery, J A Secrist, 3rd, L L Bennett, Jr
Published in Molecular pharmacology (01.02.1992)
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Published in Molecular pharmacology (01.02.1992)
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