Comparison of the effect of Carbovir, AZT, and dideoxynucleoside triphosphates on the activity of human immunodeficiency virus reverse transcriptase and selected human polymerases
White, E.Lucile, Parker, William B., Macy, Lisa J., Shaddix, Sue C., McCaleb, George, Secrist, John A., Vince, Robert, Shannon, William M.
Published in Biochemical and biophysical research communications (15.06.1989)
Published in Biochemical and biophysical research communications (15.06.1989)
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Journal Article
Inosine analogs as anti-leishmanial agents
Rainey, P, Nolan, P A, Townsend, L B, Robins, R K, Fox, J J, Secrist Iii, J A, Santi, D V
Published in Pharmaceutical research (01.09.1985)
Published in Pharmaceutical research (01.09.1985)
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5'-deoxy-5'-methylthioadenosine phosphorylase--IV. Biological activity of 2-fluoroadenine-substituted 5'-deoxy-5'-methylthioadenosine analogs
Savarese, T M, Cannistra, A J, Parks, Jr, R E, Secrist, 3rd, J A, Shortnacy, A T, Montgomery, J A
Published in Biochemical pharmacology (15.06.1987)
Published in Biochemical pharmacology (15.06.1987)
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Journal Article
Improved synthesis and antitumor activity of 2-bromo-2'-deoxyadenosine
Huang, Minchi, Avery, Thomas L, Blakeley, Raymond L, Secrist, John A, Montgomery, John A
Published in Journal of medicinal chemistry (01.06.1984)
Published in Journal of medicinal chemistry (01.06.1984)
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Journal Article
Antitumor activity of 2-fluoro-2'-deoxyadenosine against tumors that express Escherichia coli purine nucleoside phosphorylase
Parker, William B, Allan, Paula W, Hassan, Abdalla E A, Secrist, 3rd, John A, Sorscher, Eric J, Waud, William R
Published in Cancer gene therapy (01.01.2003)
Published in Cancer gene therapy (01.01.2003)
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Journal Article
Antibiotic-mediated chemoprotection enhances adaptation of E. coli PNP for herpes simplex virus-based glioma therapy
Bharara, Suman, Sorscher, Eric J, Gillespie, G Yancey, Lindsey, J Russell, Hong, Jeong S, Curlee, Kimberly V, Allan, Paula W, Gadi, V K, Alexander, Sherrie A, Secrist, 3rd, John A, Parker, William B, Waud, William R
Published in Human gene therapy (01.03.2005)
Published in Human gene therapy (01.03.2005)
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Journal Article
Enhancement of Nucleoside Cytotoxicity through Nucleotide Prodrugs
Rose, Jerry D, Parker, William B, Someya, Hitoshi, Shaddix, Sue C, Montgomery, John A, Secrist, John A
Published in Journal of medicinal chemistry (26.09.2002)
Published in Journal of medicinal chemistry (26.09.2002)
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Journal Article
In vivo gene therapy of cancer with E. coli purine nucleoside phosphorylase
Parker, W B, King, S A, Allan, P W, Bennett, Jr, L L, Secrist, 3rd, J A, Montgomery, J A, Gilbert, K S, Waud, W R, Wells, A H, Gillespie, G Y, Sorscher, E J
Published in Human gene therapy (20.09.1997)
Published in Human gene therapy (20.09.1997)
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Journal Article
Synthesis and biological activity of 2'-deoxy-4'-thio pyrimidine nucleosides
Secrist, John A, Tiwari, Kamal N, Riordan, James M, Montgomery, John A
Published in Journal of medicinal chemistry (01.08.1991)
Published in Journal of medicinal chemistry (01.08.1991)
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Journal Article
Structure-based design of inhibitors of purine nucleoside phosphorylase. 1. 9-(Arylmethyl) derivatives of 9-deazaguanine
Montgomery, John A., Niwas, Shri, Rose, Jerry D., Secrist, John A., Babu, Y. Sudhakar, Bugg, Charles E., Erion, Mark D., Guida, Wayne C., Ealick, Steven E.
Published in Journal of medicinal chemistry (1993)
Published in Journal of medicinal chemistry (1993)
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Journal Article
Effects of 2-chloro-9-(3-deoxy-2-fluoro-β-D-arabinofuranosyl)adenine on K562 cellular metabolism and the inhibition of human ribonucleotide reductase and DNA polymerases by its 5'-triphosphate
PARKER, W. B, SHADDIX, S. C, CHI-HSIUNG CHANG, WHITE, E. L, ROSE, L. M, BROCKMAN, R. W, SHORTNACY, A. T, MONTGOMERY, J. A, SECRIST, J. A, LEE BENNETT, L. JR
Published in Cancer research (Chicago, Ill.) (01.05.1991)
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Published in Cancer research (Chicago, Ill.) (01.05.1991)
Journal Article
Synthesis and Biological Activity of Certain 4‘-Thio-d-arabinofuranosylpurine Nucleosides
Secrist, John A, Tiwari, Kamal N, Shortnacy-Fowler, Anita T, Messini, Lea, Riordan, James M, Montgomery, John A, Meyers, Scott C, Ealick, Steven E
Published in Journal of medicinal chemistry (24.09.1998)
Published in Journal of medicinal chemistry (24.09.1998)
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Journal Article
Mechanism of inhibition of human immunodeficiency virus type 1 reverse transcriptase and human DNA polymerases alpha, beta, and gamma by the 5'-triphosphates of carbovir, 3'-azido-3'-deoxythymidine, 2',3'-dideoxyguanosine and 3'-deoxythymidine. A novel RNA template for the evaluation of antiretroviral drugs
W B Parker, E L White, S C Shaddix, L J Ross, R W Buckheit, Jr, J M Germany, J A Secrist, 3rd, R Vince, W M Shannon
Published in The Journal of biological chemistry (25.01.1991)
Published in The Journal of biological chemistry (25.01.1991)
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Journal Article
Properties of L1210 cells resistant to α-difluoromethylornithine
PEGG, A. E, SECRIST, J. A. III, RENTALA MADHUBALA
Published in Cancer research (Chicago, Ill.) (15.05.1988)
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Published in Cancer research (Chicago, Ill.) (15.05.1988)
Journal Article
Resolution of racemic carbocyclic analogs of purine nucleosides through the action of adenosine deaminase. Antiviral activity of the carbocyclic 2'-deoxyguanosine enantiomers
Secrist, John A, Montgomery, John A, Shealy, Y. Fulmer, O'Dell, C. Allen, Clayton, Sarah Jo
Published in Journal of medicinal chemistry (01.04.1987)
Published in Journal of medicinal chemistry (01.04.1987)
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Journal Article
Structure-based design of inhibitors of purine nucleoside phosphorylase. 3. 9-Arylmethyl derivatives of 9-deazaguanine substituted on the methylene group
Erion, M D, Niwas, S, Rose, J D, Ananthan, S, Allen, M, Secrist, 3rd, J A, Babu, Y S, Bugg, C E, Guida, W C, Ealick, S E
Published in Journal of medicinal chemistry (26.11.1993)
Published in Journal of medicinal chemistry (26.11.1993)
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