Subclone-specific microenvironmental impact and drug response in refractory multiple myeloma revealed by single‐cell transcriptomics
Tirier, Stephan M., Mallm, Jan-Philipp, Steiger, Simon, Poos, Alexandra M., Awwad, Mohamed H. S., Giesen, Nicola, Casiraghi, Nicola, Susak, Hana, Bauer, Katharina, Baumann, Anja, John, Lukas, Seckinger, Anja, Hose, Dirk, Müller-Tidow, Carsten, Goldschmidt, Hartmut, Stegle, Oliver, Hundemer, Michael, Weinhold, Niels, Raab, Marc S., Rippe, Karsten
Published in Nature communications (29.11.2021)
Published in Nature communications (29.11.2021)
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Progression in Smoldering Myeloma Is Independently Determined by the Chromosomal Abnormalities del(17p), t(4;14), Gain 1q, Hyperdiploidy, and Tumor Load
NEBEN, Kai, JAUCH, Anna, HOSE, Dirk, HIELSCHER, Thomas, HILLENGASS, Jens, LEHNERS, Nicola, SECKINGER, Anja, GRANZOW, Martin, RAAB, Marc S, HO, Anthony D, GOLDSCHMIDT, Hartmut
Published in Journal of clinical oncology (01.12.2013)
Published in Journal of clinical oncology (01.12.2013)
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CHEK1 and circCHEK1_246aa evoke chromosomal instability and induce bone lesion formation in multiple myeloma
Gu, Chunyan, Wang, Wang, Tang, Xiaozhu, Xu, Tingting, Zhang, Yanxin, Guo, Mengjie, Wei, Rongfang, Wang, Yajun, Jurczyszyn, Artur, Janz, Siegfried, Beksac, Meral, Zhan, Fenghuang, Seckinger, Anja, Hose, Dirk, Pan, Jingxuan, Yang, Ye
Published in Molecular cancer (05.06.2021)
Published in Molecular cancer (05.06.2021)
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Journal Article
Cytogenetic subclone formation and evolution in progressive smoldering multiple myeloma
Merz, Maximilian, Hielscher, Thomas, Schult, David, Mai, Elias K., Raab, Marc S., Hillengass, Jens, Seckinger, Anja, Hose, Dirk, Granzow, Martin, Jauch, Anna, Goldschmidt, Hartmut
Published in Leukemia (01.04.2020)
Published in Leukemia (01.04.2020)
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Journal Article
A niche-dependent myeloid transcriptome signature defines dormant myeloma cells
Khoo, Weng Hua, Ledergor, Guy, Weiner, Assaf, Roden, Daniel L., Terry, Rachael L., McDonald, Michelle M., Chai, Ryan C., De Veirman, Kim, Owen, Katie L., Opperman, Khatora S., Vandyke, Kate, Clark, Justine R., Seckinger, Anja, Kovacic, Natasa, Nguyen, Akira, Mohanty, Sindhu T., Pettitt, Jessica A., Xiao, Ya, Corr, Alexander P., Seeliger, Christine, Novotny, Mark, Lasken, Roger S., Nguyen, Tuan V., Oyajobi, Babatunde O., Aftab, Dana, Swarbrick, Alexander, Parker, Belinda, Hewett, Duncan R., Hose, Dirk, Vanderkerken, Karin, Zannettino, Andrew C.W., Amit, Ido, Phan, Tri Giang, Croucher, Peter I.
Published in Blood (04.07.2019)
Published in Blood (04.07.2019)
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Journal Article
Inhibiting the osteocyte-specific protein sclerostin increases bone mass and fracture resistance in multiple myeloma
McDonald, Michelle M., Reagan, Michaela R., Youlten, Scott E., Mohanty, Sindhu T., Seckinger, Anja, Terry, Rachael L., Pettitt, Jessica A., Simic, Marija K., Cheng, Tegan L., Morse, Alyson, Le, Lawrence M.T., Abi-Hanna, David, Kramer, Ina, Falank, Carolyne, Fairfield, Heather, Ghobrial, Irene M., Baldock, Paul A., Little, David G., Kneissel, Michaela, Vanderkerken, Karin, Bassett, J.H.Duncan, Williams, Graham R., Oyajobi, Babatunde O., Hose, Dirk, Phan, Tri G., Croucher, Peter I.
Published in Blood (29.06.2017)
Published in Blood (29.06.2017)
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Journal Article
Salvage autologous transplant and lenalidomide maintenance vs. lenalidomide/dexamethasone for relapsed multiple myeloma: the randomized GMMG phase III trial ReLApsE
Goldschmidt, Hartmut, Baertsch, Marc-Andrea, Schlenzka, Jana, Becker, Natalia, Habermehl, Christina, Hielscher, Thomas, Raab, Marc-Steffen, Hillengass, Jens, Sauer, Sandra, Müller-Tidow, Carsten, Luntz, Steffen, Jauch, Anna, Hose, Dirk, Seckinger, Anja, Brossart, Peter, Goerner, Martin, Klein, Stefan, Schmidt-Hieber, Martin, Reimer, Peter, Graeven, Ullrich, Fenk, Roland, Haenel, Mathias, Martin, Hans, Lindemann, Hans W., Scheid, Christoph, Nogai, Axel, Salwender, Hans, Noppeney, Richard, Besemer, Britta, Weisel, Katja
Published in Leukemia (01.04.2021)
Published in Leukemia (01.04.2021)
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RFWD2 induces cellular proliferation and selective proteasome inhibitor resistance by mediating P27 ubiquitination in multiple myeloma
Gu, Chunyan, Lu, Ting, Wang, Wang, Shao, Miaomiao, Wei, Rongfang, Guo, Mengjie, Li, Rui, Qiao, Li, Hu, Ye, Zhan, Fenghuang, Seckinger, Anja, Hose, Dirk, Yang, Ye
Published in Leukemia (01.06.2021)
Published in Leukemia (01.06.2021)
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Journal Article
JunB is a key regulator of multiple myeloma bone marrow angiogenesis
Fan, Fengjuan, Malvestiti, Stefano, Vallet, Sonia, Lind, Judith, Garcia-Manteiga, Jose Manuel, Morelli, Eugenio, Jiang, Qinyue, Seckinger, Anja, Hose, Dirk, Goldschmidt, Hartmut, Stadlbauer, Andreas, Sun, Chunyan, Mei, Heng, Pecherstorfer, Martin, Bakiri, Latifa, Wagner, Erwin F., Tonon, Giovanni, Sattler, Martin, Hu, Yu, Tassone, Pierfrancesco, Jaeger, Dirk, Podar, Klaus
Published in Leukemia (01.12.2021)
Published in Leukemia (01.12.2021)
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Journal Article
Kinome expression profiling to target new therapeutic avenues in multiple myeloma
de Boussac, Hugues, Bruyer, Angélique, Jourdan, Michel, Maes, Anke, Robert, Nicolas, Gourzones, Claire, Vincent, Laure, Seckinger, Anja, Cartron, Guillaume, Hose, Dirk, De Bruyne, Elke, Kassambara, Alboukadel, Pasero, Philippe, Moreaux, Jérôme
Published in Haematologica (Roma) (01.03.2020)
Published in Haematologica (Roma) (01.03.2020)
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Journal Article
Response-adapted lenalidomide maintenance in newly diagnosed myeloma: results from the phase III GMMG-MM5 trial
Goldschmidt, Hartmut, Mai, Elias K., Dürig, Jan, Scheid, Christof, Weisel, Katja C., Kunz, Christina, Bertsch, Uta, Hielscher, Thomas, Merz, Maximilian, Munder, Markus, Lindemann, Hans-Walter, Hügle-Dörr, Barbara, Tichy, Diana, Giesen, Nicola, Hose, Dirk, Seckinger, Anja, Huhn, Stefanie, Luntz, Steffen, Jauch, Anna, Elmaagacli, Ahmet, Rabold, Bernhard, Fuhrmann, Stephan, Brossart, Peter, Goerner, Martin, Bernhard, Helga, Hoffmann, Martin, Hillengass, Jens, Raab, Marc S., Blau, Igor W., Hänel, Mathias, Salwender, Hans J.
Published in Leukemia (01.07.2020)
Published in Leukemia (01.07.2020)
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A tissue-based approach to selection of reference genes for quantitative real-time PCR in a sheep osteoporosis model
Schulze, Felix, Malhan, Deeksha, El Khassawna, Thaqif, Heiss, Christian, Seckinger, Anja, Hose, Dirk, Rösen-Wolff, Angela
Published in BMC genomics (19.12.2017)
Published in BMC genomics (19.12.2017)
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Comparative characteristics of mesenchymal stem cells from human bone marrow, adipose tissue, and umbilical cord blood
Wagner, Wolfgang, Wein, Frederik, Seckinger, Anja, Frankhauser, Maria, Wirkner, Ute, Krause, Ulf, Blake, Jonathon, Schwager, Christian, Eckstein, Volker, Ansorge, Wilhelm, Ho, Anthony D.
Published in Experimental hematology (01.11.2005)
Published in Experimental hematology (01.11.2005)
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Resemblance-Ranking Peptide Library to Screen for Binders to Antibodies on a Peptidomic Scale
Jenne, Felix, Biniaminov, Sergey, Biniaminov, Nathalie, Marquardt, Philipp, von Bojničić-Kninski, Clemens, Popov, Roman, Seckinger, Anja, Hose, Dirk, Nesterov-Mueller, Alexander
Published in International journal of molecular sciences (23.03.2022)
Published in International journal of molecular sciences (23.03.2022)
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Journal Article
Targeting CEACAM5-positive solid tumors using NILK-2401, a novel CEACAM5xCD47 κλ bispecific antibody
Seckinger, Anja, Buatois, Vanessa, Moine, Valéry, Daubeuf, Bruno, Richard, Françoise, Chatel, Laurence, Viandier, Alizée, Bosson, Nicolas, Rousset, Emeline, Masternak, Krzysztof, Salgado-Pires, Susana, Batista, Claudia, Mougin, Christelle, Juan-Bégeot, Flora, Poitevin, Yves, Hose, Dirk
Published in Frontiers in immunology (24.04.2024)
Published in Frontiers in immunology (24.04.2024)
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Journal Article
Bortezomib-based induction, high-dose melphalan and lenalidomide maintenance in myeloma up to 70 years of age
Mai, Elias K., Miah, Kaya, Bertsch, Uta, Dürig, Jan, Scheid, Christof, Weisel, Katja C., Kunz, Christina, Munder, Markus, Lindemann, Hans-Walter, Merz, Maximilian, Hose, Dirk, Jauch, Anna, Seckinger, Anja, Luntz, Steffen, Sauer, Sandra, Fuhrmann, Stephan, Brossart, Peter, Elmaagacli, Ahmet, Goerner, Martin, Bernhard, Helga, Hoffmann, Martin, Raab, Marc S., Blau, Igor W., Hänel, Mathias, Benner, Axel, Salwender, Hans J., Goldschmidt, Hartmut
Published in Leukemia (01.03.2021)
Published in Leukemia (01.03.2021)
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Journal Article
DNMTi/HDACi combined epigenetic targeted treatment induces reprogramming of myeloma cells in the direction of normal plasma cells
Bruyer, Angelique, Maes, Ken, Herviou, Laurie, Kassambara, Alboukadel, Seckinger, Anja, Cartron, Guillaume, Rème, Thierry, Robert, Nicolas, Requirand, Guilhem, Boireau, Stéphanie, Müller-Tidow, Carsten, Veyrune, Jean-luc, Vincent, Laure, Bouhya, Salahedine, Goldschmidt, Hartmut, Vanderkerken, Karin, Hose, Dirk, Klein, Bernard, De Bruyne, Elke, Moreaux, Jerome
Published in British journal of cancer (01.04.2018)
Published in British journal of cancer (01.04.2018)
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Journal Article
CD38 as Immunotherapeutic Target in Light Chain Amyloidosis and Multiple Myeloma-Association With Molecular Entities, Risk, Survival, and Mechanisms of Upfront Resistance
Seckinger, Anja, Hillengass, Jens, Emde, Martina, Beck, Susanne, Kimmich, Christoph, Dittrich, Tobias, Hundemer, Michael, Jauch, Anna, Hegenbart, Ute, Raab, Marc-Steffen, Ho, Anthony D, Schönland, Stefan, Hose, Dirk
Published in Frontiers in immunology (20.07.2018)
Published in Frontiers in immunology (20.07.2018)
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Journal Article
The BLM helicase is a new therapeutic target in multiple myeloma involved in replication stress survival and drug resistance
Ovejero, Sara, Viziteu, Elena, Dutrieux, Laure, Devin, Julie, Lin, Yea-Lih, Alaterre, Elina, Jourdan, Michel, Basbous, Jihane, Requirand, Guilhem, Robert, Nicolas, de Boussac, Hugues, Seckinger, Anja, Hose, Dirk, Vincent, Laure, Herbaux, Charles, Constantinou, Angelos, Pasero, Philippe, Moreaux, Jérôme
Published in Frontiers in immunology (09.12.2022)
Published in Frontiers in immunology (09.12.2022)
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Journal Article
Long-term follow-up of subcutaneous versus intravenous bortezomib during induction therapy for newly diagnosed multiple myeloma treated within the GMMG-MM5 Phase III Trial
Salwender, Hans, Elmaagacli, Ahmet, Merz, Maximilian, Miah, Kaya, Benner, Axel, Haenel, Mathias, Jehn, Christian, Mai, Elias K., Bertsch, Uta, Blau, Igor W., Scheid, Christof, Hose, Dirk, Seckinger, Anja, Jauch, Anna, Raab, Marc S., Luntz, Steffen P., Besemer, Britta, Munder, Markus, Brossart, Peter, Fuhrmann, Stephan, Lindemann, Hans-Walter, Weisel, Katja, Duerig, Jan, Goldschmidt, Hartmut
Published in Leukemia (01.10.2021)
Published in Leukemia (01.10.2021)
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