Acazicolcept (ALPN-101), a dual ICOS/CD28 antagonist, demonstrates efficacy in systemic sclerosis preclinical mouse models
Orvain, Cindy, Cauvet, Anne, Prudent, Alexis, Guignabert, Christophe, Thuillet, Raphaël, Ottaviani, Mina, Tu, Ly, Duhalde, Fanny, Nicco, Carole, Batteux, Frédéric, Avouac, Jérôme, Wang, NingXin, Seaberg, Michelle A, Dillon, Stacey R, Allanore, Yannick
Published in Arthritis research & therapy (05.01.2022)
Published in Arthritis research & therapy (05.01.2022)
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Povetacicept, an Enhanced Dual APRIL/BAFF Antagonist That Modulates B Lymphocytes and Pathogenic Autoantibodies for the Treatment of Lupus and Other B Cell–Related Autoimmune Diseases
Evans, Lawrence S., Lewis, Katherine E., DeMonte, Daniel, Bhandari, Janhavi G., Garrett, Logan B., Kuijper, Joseph L., Ardourel, Daniel, Wolfson, Martin F., Debrot, Susan, Mudri, Sherri, Kleist, Kayla, Griffin, Luana L., Hebb, LuAnne, Sanderson, Russell J., Wang, NingXin, Seaberg, Michelle, Chunyk, Allison G., Yang, Jing, Hong, Youji, Maria, Zahra, Messenheimer, David J., Holland, Pamela M., Peng, Stanford L., Rixon, Mark W., Dillon, Stacey R.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.07.2023)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.07.2023)
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Abstract 1740: Engineered variant domain fusion proteins provide checkpoint inhibition and tumor antigen dependent CD28 costimulation resulting in potent anti-tumor immunity
Levin, Steven D., Maurer, Mark F., Gudgeon, Chelsea, Chandrasekaran, Siddarth, Ardourel, Daniel, Demonte, Daniel, Kuijper, Joseph, Wolfson, Martin, Garrett, Logan, Kleist, Kayla N., Mudri, Sherri, Nguyen, Hieu, Seaberg, Michelle, Wang, Rachel, Yang, Jing, Lewis, Katherine E., Dillon, Stacey R., Rixon, Mark, Peng, Stanford L.
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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ICOSL + plasmacytoid dendritic cells as inducer of graft-versus-host disease, responsive to a dual ICOS/CD28 antagonist
Adom, Djamilatou, Dillon, Stacey R, Yang, Jinfeng, Liu, Hao, Ramadan, Abdulraouf, Kushekhar, Kushi, Hund, Samantha, Albright, Amanda, Kirksey, Maykala, Adeniyan, Titilayo, Lewis, Katherine E, Evans, Lawrence, Wu, Rebecca, Levin, Steven D, Mudri, Sherri, Yang, Jing, Rickel, Erika, Seaberg, Michelle, Henderson, Katherine, Gudgeon, Chelsea J, Wolfson, Martin F, Swanson, Ryan M, Swiderek, Kristine M, Peng, Stanford L, Hippen, Keli L, Blazar, Bruce R, Paczesny, Sophie
Published in Science translational medicine (07.10.2020)
Published in Science translational medicine (07.10.2020)
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Acazicolcept (ALPN-101), a dual ICOS/CD28 antagonist, demonstrates efficacy in systemic sclerosis preclinical mouse models
Orvain, Cindy, Cauvet, Anne, Prudent, Alexis, Guignabert, Christophe, Thuillet, Raphaël, Ottaviani, Mina, Tu, Ly, Duhalde, Fanny, Nicco, Carole, Batteux, Frédéric, Avouac, Jérôme, Wang, Ningxin, Seaberg, Michelle, Dillon, Stacey, Allanore, Yannick
Published in Arthritis research & therapy (01.12.2022)
Published in Arthritis research & therapy (01.12.2022)
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244 - A Dual ICOS/CD28 Antagonist ICOSL Variant Ig Domain (vIgD) Potently Suppresses Human Mixed Lymphocyte Reactions and Human/NSG Mouse Xenograft Graft vs. Host Disease (GvHD)
Dillon, Stacey R., Lewis, Katherine E., Swanson, Ryan, Evans, Lawrence S., Kornacker, Michael G., Levin, Steven D., Wolfson, Martin F., Rickel, Erika, Bort, Susan J., Moss, Aaron M., Seaberg, Michelle A., Bhandari, Janhavi, MacNeil, Sean, Hoover, Joe, Rixon, Mark W., Peng, Stanford L.
Published in Biology of blood and marrow transplantation (01.03.2018)
Published in Biology of blood and marrow transplantation (01.03.2018)
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A Dual ICOS/CD28 Antagonist ICOSL Variant Ig Domain (vIgD) Potently Suppresses Human Mixed Lymphocyte Reactions and Human/NSG Mouse Xenograft Graft vs. Host Disease (GvHD)
Dillon, Stacey R., Lewis, Katherine E., Swanson, Ryan, Evans, Lawrence S., Kornacker, Michael G., Levin, Steven D., Wolfson, Martin F., Rickel, Erika, Bort, Susan J., Moss, Aaron M., Seaberg, Michelle A., Bhandari, Janhavi, MacNeil, Sean, Hoover, Joe, Rixon, Mark W., Peng, Stanford L.
Published in Biology of blood and marrow transplantation (01.03.2018)
Published in Biology of blood and marrow transplantation (01.03.2018)
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Plasma/Serum Levels of flt3 Ligand Are Low in Normal Individuals and Highly Elevated in Patients With Fanconi Anemia and Acquired Aplastic Anemia
Lyman, Stewart D., Seaberg, Michelle, Hanna, Roberta, Zappone, JoDee, Brasel, Ken, Abkowitz, Janis L., Prchal, Josef T., Schultz, John C., Shahidi, Nasrollah T.
Published in Blood (01.12.1995)
Published in Blood (01.12.1995)
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