Dual-Action Combination Therapy Enhances Angiogenesis while Reducing Tumor Growth and Spread
Wong, Ping-Pui, Demircioglu, Fevzi, Ghazaly, Essam, Alrawashdeh, Wasfi, Stratford, Michael R.L., Scudamore, Cheryl L., Cereser, Biancastella, Crnogorac-Jurcevic, Tatjana, McDonald, Stuart, Elia, George, Hagemann, Thorsten, Kocher, Hemant M., Hodivala-Dilke, Kairbaan M.
Published in Cancer cell (12.01.2015)
Published in Cancer cell (12.01.2015)
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HOIL‐1 ubiquitin ligase activity targets unbranched glucosaccharides and is required to prevent polyglucosan accumulation
Kelsall, Ian R, McCrory, Elisha H, Xu, Yingqi, Scudamore, Cheryl L, Nanda, Sambit K, Mancebo‐Gamella, Paula, Wood, Nicola T, Knebel, Axel, Matthews, Stephen J, Cohen, Philip
Published in The EMBO journal (19.04.2022)
Published in The EMBO journal (19.04.2022)
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Hypoxia-sensing CAR T cells provide safety and efficacy in treating solid tumors
Kosti, Paris, Opzoomer, James W., Larios-Martinez, Karen I., Henley-Smith, Rhonda, Scudamore, Cheryl L., Okesola, Mary, Taher, Mustafa Y.M., Davies, David M., Muliaditan, Tamara, Larcombe-Young, Daniel, Woodman, Natalie, Gillett, Cheryl E., Thavaraj, Selvam, Maher, John, Arnold, James N.
Published in Cell reports. Medicine (20.04.2021)
Published in Cell reports. Medicine (20.04.2021)
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Gadd45γ and Map3k4 Interactions Regulate Mouse Testis Determination via p38 MAPK-Mediated Control of Sry Expression
Warr, Nick, Carre, Gwenn-Aël, Siggers, Pam, Faleato, Jessica Vitos, Brixey, Rachel, Pope, Madeleine, Bogani, Debora, Childers, Melissa, Wells, Sara, Scudamore, Cheryl L., Tedesco, Marianna, del Barco Barrantes, Ivan, Nebreda, Angel R., Trainor, Paul A., Greenfield, Andy
Published in Developmental cell (13.11.2012)
Published in Developmental cell (13.11.2012)
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Vps34 PI 3-kinase inactivation enhances insulin sensitivity through reprogramming of mitochondrial metabolism
Bilanges, Benoit, Alliouachene, Samira, Pearce, Wayne, Morelli, Daniele, Szabadkai, Gyorgy, Chung, Yuen-Li, Chicanne, Gaëtan, Valet, Colin, Hill, Julia M, Voshol, Peter J, Collinson, Lucy, Peddie, Christopher, Ali, Khaled, Ghazaly, Essam, Rajeeve, Vinothini, Trichas, Georgios, Srinivas, Shankar, Chaussade, Claire, Salamon, Rachel S, Backer, Jonathan M, Scudamore, Cheryl L, Whitehead, Maria A, Keaney, Erin P, Murphy, Leon O, Semple, Robert K, Payrastre, Bernard, Tooze, Sharon A, Vanhaesebroeck, Bart
Published in Nature communications (27.11.2017)
Published in Nature communications (27.11.2017)
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Why are the phenotypes of TRAF6 knock-in and TRAF6 knock-out mice so different?
Petrova, Tsvetana, Bennett, Kyle, Nanda, Sambit, Strickson, Sam, Scudamore, Cheryl L, Prescott, Alan R, Cohen, Philip
Published in PloS one (14.02.2022)
Published in PloS one (14.02.2022)
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Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling
Berenjeno, Inma M, Piñeiro, Roberto, Castillo, Sandra D, Pearce, Wayne, McGranahan, Nicholas, Dewhurst, Sally M, Meniel, Valerie, Birkbak, Nicolai J, Lau, Evelyn, Sansregret, Laurent, Morelli, Daniele, Kanu, Nnennaya, Srinivas, Shankar, Graupera, Mariona, Parker, Victoria E R, Montgomery, Karen G, Moniz, Larissa S, Scudamore, Cheryl L, Phillips, Wayne A, Semple, Robert K, Clarke, Alan, Swanton, Charles, Vanhaesebroeck, Bart
Published in Nature communications (24.11.2017)
Published in Nature communications (24.11.2017)
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Exploring the Lean Phenotype of Glutathione-Depleted Mice: Thiol, Amino Acid and Fatty Acid Profiles
Elshorbagy, Amany K, Jernerén, Fredrik, Scudamore, Cheryl L, McMurray, Fiona, Cater, Heather, Hough, Tertius, Cox, Roger, Refsum, Helga
Published in PloS one (27.10.2016)
Published in PloS one (27.10.2016)
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Disruption of mouse Cenpj, a regulator of centriole biogenesis, phenocopies Seckel syndrome
McIntyre, Rebecca E, Lakshminarasimhan Chavali, Pavithra, Ismail, Ozama, Carragher, Damian M, Sanchez-Andrade, Gabriela, Forment, Josep V, Fu, Beiyuan, Del Castillo Velasco-Herrera, Martin, Edwards, Andrew, van der Weyden, Louise, Yang, Fengtang, Ramirez-Solis, Ramiro, Estabel, Jeanne, Gallagher, Ferdia A, Logan, Darren W, Arends, Mark J, Tsang, Stephen H, Mahajan, Vinit B, Scudamore, Cheryl L, White, Jacqueline K, Jackson, Stephen P, Gergely, Fanni, Adams, David J
Published in PLoS genetics (01.11.2012)
Published in PLoS genetics (01.11.2012)
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Systemic silencing of PHD2 causes reversible immune regulatory dysfunction
Yamamoto, Atsushi, Hester, Joanna, Macklin, Philip S, Kawai, Kento, Uchiyama, Masateru, Biggs, Daniel, Bishop, Tammie, Bull, Katherine, Cheng, Xiaotong, Cawthorne, Eleanor, Coleman, Mathew L, Crockford, Tanya L, Davies, Ben, Dow, Lukas E, Goldin, Rob, Kranc, Kamil, Kudo, Hiromi, Lawson, Hannah, McAuliffe, James, Milward, Kate, Scudamore, Cheryl L, Soilleux, Elizabeth, Issa, Fadi, Ratcliffe, Peter J, Pugh, Chris W
Published in The Journal of clinical investigation (01.09.2019)
Published in The Journal of clinical investigation (01.09.2019)
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Tracking preleukemic cells in vivo to reveal the sequence of molecular events in radiation leukemogenesis
Verbiest, Tom, Finnon, Rosemary, Brown, Natalie, Cruz-Garcia, Lourdes, Finnon, Paul, O'Brien, Grainne, Ross, Eleanor, Bouffler, Simon, Scudamore, Cheryl L, Badie, Christophe
Published in Leukemia (01.06.2018)
Published in Leukemia (01.06.2018)
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Modification of an aggressive model of Alport Syndrome reveals early differences in disease pathogenesis due to genetic background
Falcone, Sara, Wisby, Laura, Nicol, Thomas, Blease, Andrew, Starbuck, Becky, Parker, Andrew, Sanderson, Jeremy, Brown, Steve D M, Scudamore, Cheryl L, Pusey, Charles D, Tam, Frederick W K, Potter, Paul K
Published in Scientific reports (31.12.2019)
Published in Scientific reports (31.12.2019)
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Comprehensive phenotypic analysis of the Dp1Tyb mouse strain reveals a broad range of Down syndrome-related phenotypes
Lana-Elola, Eva, Cater, Heather, Watson-Scales, Sheona, Greenaway, Simon, Müller-Winkler, Jennifer, Gibbins, Dorota, Nemes, Mihaela, Slender, Amy, Hough, Tertius, Keskivali-Bond, Piia, Scudamore, Cheryl L, Herbert, Eleanor, Banks, Gareth T, Mobbs, Helene, Canonica, Tara, Tosh, Justin, Noy, Suzanna, Llorian, Miriam, Nolan, Patrick M, Griffin, Julian L, Good, Mark, Simon, Michelle, Mallon, Ann-Marie, Wells, Sara, Fisher, Elizabeth M C, Tybulewicz, Victor L J
Published in Disease models & mechanisms (01.10.2021)
Published in Disease models & mechanisms (01.10.2021)
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High-fat feeding rapidly induces obesity and lipid derangements in C57BL/6N mice
Podrini, Christine, Cambridge, Emma L, Lelliott, Christopher J, Carragher, Damian M, Estabel, Jeanne, Gerdin, Anna-Karin, Karp, Natasha A, Scudamore, Cheryl L, Ramirez-Solis, Ramiro, White, Jacqueline K
Published in Mammalian genome (01.06.2013)
Published in Mammalian genome (01.06.2013)
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Pharmacological inhibition of FTO
McMurray, Fiona, Demetriades, Marina, Aik, WeiShen, Merkestein, Myrte, Kramer, Holger, Andrew, Daniel S, Scudamore, Cheryl L, Hough, Tertius A, Wells, Sara, Ashcroft, Frances M, McDonough, Michael A, Schofield, Christopher J, Cox, Roger D
Published in PloS one (01.04.2015)
Published in PloS one (01.04.2015)
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The occurrence of tarsal injuries in male mice of C57BL/6N substrains in multiple international mouse facilities
Herbert, Eleanor, Stewart, Michelle, Hutchison, Marie, Flenniken, Ann M, Qu, Dawei, Nutter, Lauryl M J, McKerlie, Colin, Hobson, Liane, Kick, Brenda, Lyons, Bonnie, Wiegand, Jean-Paul, Doty, Rosalinda, Aguilar-Pimentel, Juan Antonio, Hrabe de Angelis, Martin, Dickinson, Mary, Seavitt, John, White, Jacqueline K, Scudamore, Cheryl L, Wells, Sara
Published in PloS one (15.06.2020)
Published in PloS one (15.06.2020)
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Spi1 R235C point mutation confers hypersensitivity to radiation-induced acute myeloid leukemia in mice
Brown, Natalie, Finnon, Rosemary, Finnon, Paul, McCarron, Roisin, Cruz-Garcia, Lourdes, O’Brien, Grainne, Herbert, Eleanor, Scudamore, Cheryl L., Morel, Edouard, Badie, Christophe
Published in iScience (15.09.2023)
Published in iScience (15.09.2023)
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An N-Ethyl-N-Nitrosourea Induced Corticotropin-Releasing Hormone Promoter Mutation Provides a Mouse Model for Endogenous Glucocorticoid Excess
Bentley, Liz, Esapa, Christopher T, Nesbit, M. Andrew, Head, Rosie A, Evans, Holly, Lath, Darren, Scudamore, Cheryl L, Hough, Tertius A, Podrini, Christine, Hannan, Fadil M, Fraser, William D, Croucher, Peter I, Brown, Matthew A, Brown, Steve D. M, Cox, Roger D, Thakker, Rajesh V
Published in Endocrinology (Philadelphia) (01.03.2014)
Published in Endocrinology (Philadelphia) (01.03.2014)
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Targeting of Slc25a21 is associated with orofacial defects and otitis media due to disrupted expression of a neighbouring gene
Maguire, Simon, Estabel, Jeanne, Ingham, Neil, Pearson, Selina, Ryder, Edward, Carragher, Damian M, Walker, Nicolas, Bussell, James, Chan, Wai-In, Keane, Thomas M, Adams, David J, Scudamore, Cheryl L, Lelliott, Christopher J, Ramírez-Solis, Ramiro, Karp, Natasha A, Steel, Karen P, White, Jacqueline K, Gerdin, Anna-Karin
Published in PloS one (18.03.2014)
Published in PloS one (18.03.2014)
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