Identification of triple-negative breast cancer cell lines classified under the same molecular subtype using different molecular characterization techniques: Implications for translational research
Espinosa Fernandez, Jose Rodrigo, Eckhardt, Bedrich L, Lee, Jangsoon, Lim, Bora, Pearson, Troy, Seitz, Rob S, Hout, David R, Schweitzer, Brock L, Nielsen, Tyler J, Lawrence, O Rayne, Wang, Ying, Rao, Arvind, Ueno, Naoto T
Published in PloS one (30.04.2020)
Published in PloS one (30.04.2020)
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An Immune-Related Gene Expression Signature Predicts Benefit from Adding Atezolizumab to FOLFOXIRI plus Bevacizumab in Metastatic Colorectal Cancer
Antoniotti, Carlotta, Boccaccino, Alessandra, Seitz, Robert, Giordano, Mirella, Catteau, Aurélie, Rossini, Daniele, Pietrantonio, Filippo, Salvatore, Lisa, McGregor, Kimberly, Bergamo, Francesca, Conca, Veronica, Leonetti, Simone, Morano, Federica, Papiani, Giorgio, Tamburini, Emiliano, Bensi, Maria, Murgioni, Sabina, Ross, Douglas Teller, Passardi, Alessandro, Boquet, Isabelle, Nielsen, Tyler J, Galon, Jérôme, Varga, Matthew Gordon, Schweitzer, Brock L, Cremolini, Chiara
Published in Clinical cancer research (13.06.2023)
Published in Clinical cancer research (13.06.2023)
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Association of a novel 27-gene immuno-oncology assay with efficacy of immune checkpoint inhibitors in advanced non-small cell lung cancer
Ranganath, Harsha, Jain, Amit L, Smith, Justin R, Ryder, Julie, Chaudry, Amina, Miller, Emily, Hare, Felicia, Valasareddy, Poojitha, Seitz, Robert S, Hout, David R, Varga, Matthew G, Schweitzer, Brock L, Nielsen, Tyler J, Mullins, Janice, Ross, Douglas T, Gandara, David R, Vidal, Gregory A
Published in BMC cancer (14.04.2022)
Published in BMC cancer (14.04.2022)
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Journal Article
The Immune-Related 27-Gene Signature DetermaIO Predicts Response to Neoadjuvant Atezolizumab plus Chemotherapy in Triple-Negative Breast Cancer
Dugo, Matteo, Huang, Chiun-Sheng, Egle, Daniel, Bermejo, Begoña, Zamagni, Claudio, Seitz, Robert S, Nielsen, Tyler J, Thill, Marc, Antón-Torres, Antonio, Russo, Stefania, Ciruelos, Eva Maria, Schweitzer, Brock L, Ross, Douglas T, Galbardi, Barbara, Greil, Richard, Semiglazov, Vladimir, Gyorffy, Balázs, Colleoni, Marco, Kelly, Catherine M, Mariani, Gabriella, Del Mastro, Lucia, Blasi, Olivia, Callari, Maurizio, Pusztai, Lajos, Valagussa, Pinuccia, Viale, Giuseppe, Gianni, Luca, Bianchini, Giampaolo
Published in Clinical cancer research (23.09.2024)
Published in Clinical cancer research (23.09.2024)
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Translation of the 27-gene immuno-oncology test (IO score) to predict outcomes in immune checkpoint inhibitor treated metastatic urothelial cancer patients
Seitz, Robert S, Hurwitz, Michael E, Nielsen, Tyler J, Bailey, Daniel B, Varga, Matthew G, Ring, Brian Z, Metts, Carrie F, Schweitzer, Brock L, McGregor, Kimberly, Ross, Douglas T
Published in Journal of translational medicine (16.08.2022)
Published in Journal of translational medicine (16.08.2022)
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Journal Article
The 27-gene IO score is associated with efficacy of PD-1/L1 inhibitors independent of FGFR expression in a real-world metastatic urothelial carcinoma cohort
Nielsen, Tyler J., Varga, Matthew G., Cronister, Catherine T., Ring, Brian Z., Seitz, Robert S., Ross, Douglas T., Schweitzer, Brock L., McGregor, Kimberly
Published in Cancer Immunology, Immunotherapy (01.07.2023)
Published in Cancer Immunology, Immunotherapy (01.07.2023)
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Journal Article
Generation of an algorithm based on minimal gene sets to clinically subtype triple negative breast cancer patients
Ring, Brian Z, Hout, David R, Morris, Stephan W, Lawrence, Kasey, Schweitzer, Brock L, Bailey, Daniel B, Lehmann, Brian D, Pietenpol, Jennifer A, Seitz, Robert S
Published in BMC cancer (23.02.2016)
Published in BMC cancer (23.02.2016)
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Journal Article
A Novel Immunomodulatory 27-Gene Signature to Predict Response to Neoadjuvant Immunochemotherapy for Primary Triple-Negative Breast Cancer
Iwase, Toshiaki, Blenman, Kim R M, Li, Xiaotong, Reisenbichler, Emily, Seitz, Robert, Hout, David, Nielsen, Tyler J, Schweitzer, Brock L, Bailey, Daniel B, Shen, Yichao, Zhang, Xiang, Pusztai, Lajos, Ueno, Naoto T
Published in Cancers (28.09.2021)
Published in Cancers (28.09.2021)
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Journal Article
Comparison of triple-negative breast cancer molecular subtyping using RNA from matched fresh-frozen versus formalin-fixed paraffin-embedded tissue
Jovanović, Bojana, Sheng, Quanhu, Seitz, Robert S, Lawrence, Kasey D, Morris, Stephan W, Thomas, Lance R, Hout, David R, Schweitzer, Brock L, Guo, Yan, Pietenpol, Jennifer A, Lehmann, Brian D
Published in BMC cancer (04.04.2017)
Published in BMC cancer (04.04.2017)
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Journal Article
Performance of a RT-PCR Assay in Comparison to FISH and Immunohistochemistry for the Detection of ALK in Non-Small Cell Lung Cancer
Hout, David R, Schweitzer, Brock L, Lawrence, Kasey, Morris, Stephan W, Tucker, Tracy, Mazzola, Rosetta, Skelton, Rachel, McMahon, Frank, Handshoe, John, Lesperance, Mary, Karsan, Aly, Saltman, David L
Published in Cancers (01.08.2017)
Published in Cancers (01.08.2017)
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Journal Article
A novel immuno-oncology algorithm measuring tumor microenvironment to predict response to immunotherapies
Nielsen, Tyler J., Ring, Brian Z., Seitz, Robert S., Hout, David R., Schweitzer, Brock L.
Published in Heliyon (01.03.2021)
Published in Heliyon (01.03.2021)
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Journal Article
27-gene Immuno-Oncology (IO) Score is Associated With Efficacy of Checkpoint Immunotherapy in Advanced NSCLC: A Retrospective BC Cancer Study
Saltman, David L., Varga, Matthew G., Nielsen, Tyler J., Croteau, Nicole S., Lockyer, Heather M., Jain, Amit L., Vidal, Gregory A., Hout, David R., Schweitzer, Brock L., Seitz, Robert S., Ross, Douglas T., Gandara, David R.
Published in Clinical lung cancer (01.03.2023)
Published in Clinical lung cancer (01.03.2023)
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Journal Article
9 Mesenchymal features of a novel 27-gene algorithm associate with canonical tumor promoting signaling pathways which may identify therapeutic options for immunotherapy resistant patients
Nielsen, Tyler, Seitz, Rob, Ross, Douglas, Hout, David, Schweitzer, Brock
Published in Journal for immunotherapy of cancer (01.11.2020)
Published in Journal for immunotherapy of cancer (01.11.2020)
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Characterization of the tumor immune-microenvironment of adenocarcinoma of lung with a metastatic lesion in the pancreas treated successfully with first-line, single-agent pembrolizumab
Saltman, David L., Nielsen, Tyler J., Salina, Davide, Hout, David R., McMahon, Frank B., Valev, Boris R., Huk, Michael, Chandra, Pranil K., Spille, Jeremy, Seitz, Robert S., Schweitzer, Brock L.
Published in Therapeutic advances in medical oncology (2021)
Published in Therapeutic advances in medical oncology (2021)
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Journal Article
Changes in Triple-Negative Breast Cancer Molecular Subtypes in Patients Without Pathologic Complete Response After Neoadjuvant Systemic Chemotherapy
Masuda, Hiroko, Harano, Kenichi, Miura, Sakiko, Wang, Ying, Hirota, Yuko, Harada, Oi, Jolly, Mohit Kumar, Matsunaga, Yuki, Lim, Bora, Wood, Anita L, Parinyanitikul, Napa, Jin Lee, Hee, Gong, Gyungyub, George, Jason T, Levine, Herbert, Lee, Jangsoon, Wang, Xiaoping, Lucci, Anthony, Rao, Arvind, Schweitzer, Brock L, Lawrence, O Rayne, Seitz, Robert S, Morris, Stephan W, Hout, David R, Nakamura, Seigo, Krishnamurthy, Savitri, Ueno, Naoto T
Published in JCO precision oncology (01.03.2022)
Published in JCO precision oncology (01.03.2022)
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Journal Article
466 Use of a 27-gene immuno-oncology (IO) assay to associate response to single-agent immune checkpoint inhibitor (ICI) therapy in advanced-stage NSCLC patients from a large Canadian cohort
Saltman, David, Croteau, Nicole, Lockyer, Heather, Seitz, Rob, McMahon, Frank, Spille, Jeremy, Dickey, Andrea, Varga, Matthew, McGregor, Kim, Nielsen, Tyler, Hout, David, Schweitzer, Brock, Ross, Douglas, Gandara, David
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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Journal Article
Erratum to: Generation of an algorithm based on minimal gene sets to clinically subtype triple negative breast cancer patients
Ring, Brian Z, Hout, David R, Morris, Stephan W, Lawrence, Kasey, Schweitzer, Brock L, Bailey, Daniel B, Lehmann, Brian D, Pietenpol, Jennifer A, Seitz, Robert S
Published in BMC cancer (18.04.2016)
Published in BMC cancer (18.04.2016)
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Journal Article
Regulation of the Interleukin-7 Receptor α Promoter by the Ets Transcription Factors PU.1 and GA-binding Protein in Developing B Cells
DeKoter, Rodney P., Schweitzer, Brock L., Kamath, Meghana B., Jones, Darrel, Tagoh, Hiromi, Bonifer, Constanze, Hildeman, David A., Huang, Kelly J.
Published in The Journal of biological chemistry (11.05.2007)
Published in The Journal of biological chemistry (11.05.2007)
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Cutting Edge: K63-Linked Polyubiquitination of NEMO Modulates TLR Signaling and Inflammation In Vivo
Ni, Chang-Yuan, Wu, Zhao-Hui, Florence, William C, Parekh, Vrajesh V, Arrate, Maria Pia, Pierce, Steven, Schweitzer, Brock, Van Kaer, Luc, Joyce, Sebastian, Miyamoto, Shigeki, Ballard, Dean W, Oltz, Eugene M
Published in The Journal of immunology (1950) (01.06.2008)
Published in The Journal of immunology (1950) (01.06.2008)
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