Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition
Wong, Gabrielle S, Zhou, Jin, Liu, Jie Bin, Wu, Zhong, Xu, Xinsen, Li, Tianxia, Xu, David, Schumacher, Steven E, Puschhof, Jens, McFarland, James, Zou, Charles, Dulak, Austin, Henderson, Les, Xu, Peng, O'Day, Emily, Rendak, Rachel, Liao, Wei-Li, Cecchi, Fabiola, Hembrough, Todd, Schwartz, Sarit, Szeto, Christopher, Rustgi, Anil K, Wong, Kwok-Kin, Diehl, J Alan, Jensen, Karin, Graziano, Francesco, Ruzzo, Annamaria, Fereshetian, Shaunt, Mertins, Philipp, Carr, Steven A, Beroukhim, Rameen, Nakamura, Kenichi, Oki, Eiji, Watanabe, Masayuki, Baba, Hideo, Imamura, Yu, Catenacci, Daniel, Bass, Adam J
Published in Nature medicine (01.07.2018)
Published in Nature medicine (01.07.2018)
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Journal Article
Amino acid starvation sensitizes cancer cells to proteasome inhibition
Mizrachy-Schwartz, Sarit, Cohen, Noam, Klein, Shoshana, Kravchenko-Balasha, Nataly, Levitzki, Alexander
Published in IUBMB life (01.10.2010)
Published in IUBMB life (01.10.2010)
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Journal Article
Ado-Trastuzumab Emtansine for Patients With HER2-Mutant Lung Cancers: Results From a Phase II Basket Trial
Li, Bob T, Shen, Ronglai, Buonocore, Darren, Olah, Zachary T, Ni, Ai, Ginsberg, Michelle S, Ulaner, Gary A, Offin, Michael, Feldman, Daniel, Hembrough, Todd, Cecchi, Fabiola, Schwartz, Sarit, Pavlakis, Nick, Clarke, Stephen, Won, Helen H, Brzostowski, Edyta B, Riely, Gregory J, Solit, David B, Hyman, David M, Drilon, Alexander, Rudin, Charles M, Berger, Michael F, Baselga, Jose, Scaltriti, Maurizio, Arcila, Maria E, Kris, Mark G
Published in Journal of clinical oncology (20.08.2018)
Published in Journal of clinical oncology (20.08.2018)
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Journal Article
Feedback Suppression of PI3Kα Signaling in PTEN-Mutated Tumors Is Relieved by Selective Inhibition of PI3Kβ
Schwartz, Sarit, Wongvipat, John, Trigwell, Cath B., Hancox, Urs, Carver, Brett S., Rodrik-Outmezguine, Vanessa, Will, Marie, Yellen, Paige, de Stanchina, Elisa, Baselga, José, Scher, Howard I., Barry, Simon T., Sawyers, Charles L., Chandarlapaty, Sarat, Rosen, Neal
Published in Cancer cell (12.01.2015)
Published in Cancer cell (12.01.2015)
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Journal Article
An approach to suppress the evolution of resistance in BRAF V600E -mutant cancer
Xue, Yaohua, Martelotto, Luciano, Baslan, Timour, Vides, Alberto, Solomon, Martha, Mai, Trang Thi, Chaudhary, Neelam, Riely, Greg J, Li, Bob T, Scott, Kerry, Cechhi, Fabiola, Stierner, Ulrika, Chadalavada, Kalyani, de Stanchina, Elisa, Schwartz, Sarit, Hembrough, Todd, Nanjangud, Gouri, Berger, Michael F, Nilsson, Jonas, Lowe, Scott W, Reis-Filho, Jorge S, Rosen, Neal, Lito, Piro
Published in Nature medicine (01.08.2017)
Published in Nature medicine (01.08.2017)
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Journal Article
An approach to suppress the evolution of resistance in BRAF(V600E)-mutant cancer
Xue, Y. H., Martelotto, L., Baslan, T., Vides, A., Solomon, M., Mai, T. T., Chaudhary, N., Riely, G. J., Li, B. T., Scott, K., Cechhi, F., Stierner, Ulrika, Chadalavada, K., de Stanchina, E., Schwartz, S., Hembrough, T., Nanjangud, G., Nilsson, Jonas A, Lowe, S. W., Reis, J., Rosen, N., Lito, P.
Published in Nature medicine (01.08.2017)
Published in Nature medicine (01.08.2017)
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Journal Article
Abstract B200: Using “omics” to select immunotherapy and conventional therapy combinations
Schwartz, Sarit, Heaton, Robert, Tian, Yuan, Sanborn, Zack, Sellappan, Shankar, Cecchi, Fabiola, Benz, Steve, Hembrough, Todd
Published in Molecular cancer therapeutics (01.01.2018)
Published in Molecular cancer therapeutics (01.01.2018)
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Journal Article
Abstract 2666: Using “omics” to select immunotherapy and conventional therapy combinations
Schwartz, Sarit, Heaton, Robert, Tian, Yuan, Sanborn, Zack, Sellappan, Shankar, Scott, Kerry, Cecchi, Fabiola, Benz, Steve, Hembrough, Todd
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Abstract 735: HER2 protein quantification in multiple cancer indications identifies candidates for HER2 targeted therapies
Sellappan, Shankar, Schwartz, Sarit, Wertheimer, Ellen, Cecchi, Fabiola, Mamus, Steven W., Catenacci, Daniel VT, Hembrough, Todd
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Abstract 209: Proteomic analysis of therapeutic biomarkers in decalcified bone metastases
Cecchi, Fabiola, Sellappan, Shankar, Schwartz, Sarit, Gong, Chao, Darfler, Marlene, Scott, Kerry, Mamus, Steven W., Emmert-Buck, Mike, Hembrough, Todd
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Interferon α/β Enhances the Cytotoxic Response of MEK Inhibition in Melanoma
Litvin, Oren, Schwartz, Sarit, Wan, Zhenmao, Schild, Tanya, Rocco, Mark, Oh, Nul Loren, Chen, Bo-Juen, Goddard, Noel, Pratilas, Christine, Pe’er, Dana
Published in Molecular cell (05.03.2015)
Published in Molecular cell (05.03.2015)
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Journal Article
Selecting patients with stage II/III colorectal cancer for 5-fluorouracil-based adjuvant chemotherapy using proteomic analysis
Yan, Dongyao, Hong, Ji Hyung, Lee, Hee Yeon, Byun, Jae Ho, Cecchi, Fabiola, Tian, Yuan, Schwartz, Sarit, An, Eunkyung, Hembrough, Todd A.
Published in Journal of clinical oncology (01.02.2018)
Published in Journal of clinical oncology (01.02.2018)
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Journal Article
Refining the selection of patients with metastatic colorectal cancer for treatment with temozolomide using proteomic analysis of O6-methylguanine-DNA-methyltransferase
Schwartz, Sarit, Szeto, Chris, Tian, Yuan, Cecchi, Fabiola, Corallo, Salvatore, Calegari, Maria Alessandra, Di Bartolomeo, Maria, Morano, Federica, Raimondi, Alessandra, Fucà, Giovanni, Martinetti, Antonia, De Pascalis, Ivana, Martini, Maurizio, Belfiore, Antonino, Milione, Massimo, Orlandi, Armando, Barault, Ludovic, Barone, Carlo, de Braud, Filippo, Di Nicolantonio, Federica, Benz, Steve, Hembrough, Todd, Pietrantonio, Filippo
Published in European journal of cancer (1990) (01.01.2019)
Published in European journal of cancer (1990) (01.01.2019)
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Journal Article
Predicting survival in gastric cancer patients randomized to docetaxel with mass spectrometric quantitation of TUBB3
Cecchi, Fabiola, Catenacci, Daniel, Schwartz, Sarit, Tian, Yuan, Miceli, Rosalba, Pietrantonio, Filippo, Martinetti, Antonia, Di Bartolomeo, Maria, Hembrough, Todd, pellegrinelli, alessandro
Published in Annals of oncology (01.06.2017)
Published in Annals of oncology (01.06.2017)
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Journal Article
Predicting survival in gastric cancer patients randomized to docetaxel with mass spectrometric quantitation of TUBB3
Cecchi, Fabiola, Catenacci, Daniel V.T., Schwartz, Sarit, Sellappan, Shankar, Tian, Yuan, Miceli, Rosalba, Pietrantonio, Filippo, Pellegrinelli, Alessandro, Martinetti, Antonia, Di Bartolomeo, Maria, Hembrough, Todd A.
Published in Journal of clinical oncology (20.05.2017)
Published in Journal of clinical oncology (20.05.2017)
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