tracerDB: a crowdsourced fluorescent tracer database for target engagement analysis
Dopfer, Johannes, Vasta, James D, Müller, Susanne, Knapp, Stefan, Robers, Matthew B, Schwalm, Martin P
Published in Nature communications (05.07.2024)
Published in Nature communications (05.07.2024)
Get full text
Journal Article
Discovery of a Potent and Highly Isoform-Selective Inhibitor of the Neglected Ribosomal Protein S6 Kinase Beta 2 (S6K2)
Gerstenecker, Stefan, Haarer, Lisa, Schröder, Martin, Kudolo, Mark, Schwalm, Martin P., Wydra, Valentin, Serafim, Ricardo A. M., Chaikuad, Apirat, Knapp, Stefan, Laufer, Stefan, Gehringer, Matthias
Published in Cancers (13.10.2021)
Published in Cancers (13.10.2021)
Get full text
Journal Article
Crystal Structure and Inhibitor Identifications Reveal Targeting Opportunity for the Atypical MAPK Kinase ERK3
Schröder, Martin, Filippakopoulos, Panagis, Schwalm, Martin P, Ferrer, Carla A, Drewry, David H, Knapp, Stefan, Chaikuad, Apirat
Published in International journal of molecular sciences (26.10.2020)
Published in International journal of molecular sciences (26.10.2020)
Get full text
Journal Article
A Toolbox for the Generation of Chemical Probes for Baculovirus IAP Repeat Containing Proteins
Schwalm, Martin P., Berger, Lena M., Meuter, Maximilian N., Vasta, James D., Corona, Cesear R., Röhm, Sandra, Berger, Benedict-Tilman, Farges, Frederic, Beinert, Sebastian M., Preuss, Franziska, Morasch, Viktoria, Rogov, Vladimir V., Mathea, Sebastian, Saxena, Krishna, Robers, Matthew B., Müller, Susanne, Knapp, Stefan
Published in Frontiers in cell and developmental biology (26.05.2022)
Published in Frontiers in cell and developmental biology (26.05.2022)
Get full text
Journal Article
PROTAC degraders as chemical probes for studying target biology and target validation
N mec, Vclav, Schwalm, Martin P, Müller, Susanne, Knapp, Stefan
Published in Chemical Society reviews (20.09.2022)
Published in Chemical Society reviews (20.09.2022)
Get full text
Journal Article
Expanding the ligand spaces for E3 ligases for the design of protein degraders
Shah Zaib Saleem, Rahman, Schwalm, Martin P., Knapp, Stefan
Published in Bioorganic & medicinal chemistry (01.05.2024)
Published in Bioorganic & medicinal chemistry (01.05.2024)
Get full text
Journal Article
Toward effective Atg8-based ATTECs: Approaches and perspectives
Schwalm, Martin P, Knapp, Stefan, Rogov, Vladimir V
Published in Journal of cellular biochemistry (13.02.2023)
Published in Journal of cellular biochemistry (13.02.2023)
Get full text
Journal Article
Tracking the PROTAC degradation pathway in living cells highlights the importance of ternary complex measurement for PROTAC optimization
Schwalm, Martin P., Krämer, Andreas, Dölle, Anja, Weckesser, Janik, Yu, Xufen, Jin, Jian, Saxena, Krishna, Knapp, Stefan
Published in Cell chemical biology (20.07.2023)
Published in Cell chemical biology (20.07.2023)
Get full text
Journal Article
Splice variants of CK1α and CK1α-like: Comparative analysis of subcellular localization, kinase activity, and function in the Wnt signaling pathway
Gybeľ, Tomáš, Čada, Štěpán, Klementová, Darja, Schwalm, Martin P., Berger, Benedict-Tilman, Šebesta, Marek, Knapp, Stefan, Bryja, Vítězslav
Published in The Journal of biological chemistry (01.07.2024)
Published in The Journal of biological chemistry (01.07.2024)
Get full text
Journal Article
Development of the First Covalent Monopolar Spindle Kinase 1 (MPS1/TTK) Inhibitor
M. Serafim, Ricardo A, da Silva Santiago, André, Schwalm, Martin P, Hu, Zexi, dos Reis, Caio V, Takarada, Jessica E, Mezzomo, Priscila, Massirer, Katlin B, Kudolo, Mark, Gerstenecker, Stefan, Chaikuad, Apirat, Zender, Lars, Knapp, Stefan, Laufer, Stefan, Couñago, Rafael M, Gehringer, Matthias
Published in Journal of medicinal chemistry (24.02.2022)
Published in Journal of medicinal chemistry (24.02.2022)
Get full text
Journal Article
Development of Potent Dual BET/HDAC Inhibitors via Pharmacophore Merging and Structure-Guided Optimization
Bauer, Nicolas, Balourdas, Dimitrios-Ilias, Schneider, Joel R., Zhang, Xin, Berger, Lena M., Berger, Benedict-Tilman, Schwalm, Martin P., Klopp, Nick A., Siveke, Jens T., Knapp, Stefan, Joerger, Andreas C.
Published in ACS chemical biology (16.02.2024)
Published in ACS chemical biology (16.02.2024)
Get full text
Journal Article
A chemical probe to modulate human GID4 Pro/N-degron interactions
Owens, Dominic D G, Maitland, Matthew E R, Khalili Yazdi, Aliakbar, Song, Xiaosheng, Reber, Viviane, Schwalm, Martin P, Machado, Raquel A C, Bauer, Nicolas, Wang, Xu, Szewczyk, Magdalena M, Dong, Cheng, Dong, Aiping, Loppnau, Peter, Calabrese, Matthew F, Dowling, Matthew S, Lee, Jisun, Montgomery, Justin I, O'Connell, Thomas N, Subramanyam, Chakrapani, Wang, Feng, Adamson, Ella C, Schapira, Matthieu, Gstaiger, Matthias, Knapp, Stefan, Vedadi, Masoud, Min, Jinrong, Lajoie, Gilles A, Barsyte-Lovejoy, Dalia, Owen, Dafydd R, Schild-Poulter, Caroline, Arrowsmith, Cheryl H
Published in Nature chemical biology (21.05.2024)
Published in Nature chemical biology (21.05.2024)
Get full text
Journal Article
Thalidomide derivatives degrade BCL-2 by reprogramming the binding surface of CRBN
Wang, Jianhui, Heinz, Marcel, Han, Kang, Shah, Varun J., Hasselbeck, Sebastian, Schwalm, Martin P., Rathore, Rajeshwari, Hummer, Gerhard, Zhou, Jun, Dikic, Ivan, Cheng, Xinlai
Published in Cell reports physical science (15.05.2024)
Published in Cell reports physical science (15.05.2024)
Get full text
Journal Article
High throughput screening for LC3/GABARAP binders utilizing fluorescence polarization assay
Schwalm, Martin P, Dopfer, Johannes, Knapp, Stefan, Rogov, Vladimir V
Year of Publication 09.01.2024
Year of Publication 09.01.2024
Get full text
Journal Article
Tracking the PROTAC degradation pathway in living cells highlights the importance of ternary complex measurement for PROTAC optimization
Schwalm, Martin P, Kraemer, Andreas, Doelle, Anja, Janik Weckesser, Yu, Xufen, Jin, Jian, Saxena, Krishna, Knapp, Stefan
Published in bioRxiv (11.01.2023)
Published in bioRxiv (11.01.2023)
Get full text
Paper