Crystal structure of the human angiotensin-converting enzyme-lisinopril complex
Sturrock, Edward D, Acharya, K. Ravi, Natesh, Ramanathan, Schwager, Sylva L. U
Published in Nature (London) (30.01.2003)
Published in Nature (London) (30.01.2003)
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N Domain of Human Angiotensin-I-converting Enzyme: THE ROLE OF N-GLYCOSYLATION AND THE CRYSTAL STRUCTURE IN COMPLEX WITH AN N DOMAIN-SPECIFIC PHOSPHINIC INHIBITOR, RXP407
Anthony, Colin S, Corradi, Hazel R, Schwager, Sylva L.U, Redelinghuys, Pierre, Georgiadis, Dimitris, Dive, Vincent, Acharya, K. Ravi, Sturrock, Edward D
Published in The Journal of biological chemistry (12.11.2010)
Published in The Journal of biological chemistry (12.11.2010)
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Structural basis for the C-domain-selective angiotensin-converting enzyme inhibition by bradykinin-potentiating peptide b (BPPb)
Sturrock, Edward D, Lubbe, Lizelle, Cozier, Gyles E, Schwager, Sylva L U, Arowolo, Afolake T, Arendse, Lauren B, Belcher, Emma, Acharya, K Ravi
Published in Biochemical journal (31.05.2019)
Published in Biochemical journal (31.05.2019)
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Structural Details on the Binding of Antihypertensive Drugs Captopril and Enalaprilat to Human Testicular Angiotensin I-Converting Enzyme
Natesh, Ramanathan, Schwager, Sylva L. U, Evans, Hazel R, Sturrock, Edward D, Acharya, K. Ravi
Published in Biochemistry (Easton) (13.07.2004)
Published in Biochemistry (Easton) (13.07.2004)
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Journal Article
Molecular and thermodynamic mechanisms of the chloride-dependent human angiotensin-I-converting enzyme (ACE)
Yates, Christopher J, Masuyer, Geoffrey, Schwager, Sylva L U, Akif, Mohd, Sturrock, Edward D, Acharya, K Ravi
Published in The Journal of biological chemistry (17.01.2014)
Published in The Journal of biological chemistry (17.01.2014)
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Journal Article
Crystal structures of highly specific phosphinic tripeptide enantiomers in complex with the angiotensin‐I converting enzyme
Masuyer, Geoffrey, Akif, Mohd, Czarny, Bertrand, Beau, Fabrice, Schwager, Sylva L. U., Sturrock, Edward D., Isaac, R. Elwyn, Dive, Vincent, Acharya, K. Ravi
Published in The FEBS journal (01.02.2014)
Published in The FEBS journal (01.02.2014)
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Probing the Requirements for Dual Angiotensin-Converting Enzyme C‑Domain Selective/Neprilysin Inhibition
Arendse, Lauren B, Cozier, Gyles E, Eyermann, Charles J, Basarab, Gregory S, Schwager, Sylva L, Chibale, Kelly, Acharya, K. Ravi, Sturrock, Edward D
Published in Journal of medicinal chemistry (24.02.2022)
Published in Journal of medicinal chemistry (24.02.2022)
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Crystal structures of sampatrilat and sampatrilat‐Asp in complex with human ACE – a molecular basis for domain selectivity
Cozier, Gyles E., Schwager, Sylva L., Sharma, Rajni K., Chibale, Kelly, Sturrock, Edward D., Acharya, K. Ravi
Published in The FEBS journal (01.04.2018)
Published in The FEBS journal (01.04.2018)
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Interkingdom Pharmacology of Angiotensin‑I Converting Enzyme Inhibitor Phosphonates Produced by Actinomycetes
Kramer, Glenna J, Mohd, Akif, Schwager, Sylva L. U, Masuyer, Geoffrey, Acharya, K. Ravi, Sturrock, Edward D, Bachmann, Brian O
Published in ACS medicinal chemistry letters (10.04.2014)
Published in ACS medicinal chemistry letters (10.04.2014)
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Crystal Structure of the N Domain of Human Somatic Angiotensin I-converting Enzyme Provides a Structural Basis for Domain-specific Inhibitor Design
Corradi, Hazel R., Schwager, Sylva L.U., Nchinda, Aloysius T., Sturrock, Edward D., Acharya, K. Ravi
Published in Journal of molecular biology (31.03.2006)
Published in Journal of molecular biology (31.03.2006)
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Structural characterization of angiotensin I‐converting enzyme in complex with a selenium analogue of captopril
Akif, Mohd, Masuyer, Geoffrey, Schwager, Sylva L. U., Bhuyan, Bhaskar J., Mugesh, Govindasamy, Isaac, R. Elwyn, Sturrock, Edward D., Acharya, K. Ravi
Published in The FEBS journal (01.10.2011)
Published in The FEBS journal (01.10.2011)
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Journal Article
A novel angiotensin I-converting enzyme mutation (S333W) impairs N-domain enzymatic cleavage of the anti-fibrotic peptide, AcSDKP
Danilov, Sergei M, Wade, Michael S, Schwager, Sylva L, Douglas, Ross G, Nesterovitch, Andrew B, Popova, Isolda A, Hogarth, Kyle D, Bhardwaj, Nakul, Schwartz, David E, Sturrock, Edward D, Garcia, Joe G N
Published in PloS one (04.02.2014)
Published in PloS one (04.02.2014)
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Journal Article
Novel mechanism of inhibition of human angiotensin-I-converting enzyme (ACE) by a highly specific phosphinic tripeptide
Akif, Mohd, Schwager, Sylva L, Anthony, Colin S, Czarny, Bertrand, Beau, Fabrice, Dive, Vincent, Sturrock, Edward D, Acharya, K Ravi
Published in Biochemical journal (15.05.2011)
Published in Biochemical journal (15.05.2011)
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