Vascular smooth muscle cell calcification is mediated by regulated exosome secretion
Kapustin, Alexander N, Chatrou, Martijn L L, Drozdov, Ignat, Zheng, Ying, Davidson, Sean M, Soong, Daniel, Furmanik, Malgorzata, Sanchis, Pilar, De Rosales, Rafael Torres Martin, Alvarez-Hernandez, Daniel, Shroff, Rukshana, Yin, Xiaoke, Muller, Karin, Skepper, Jeremy N, Mayr, Manuel, Reutelingsperger, Chris P, Chester, Adrian, Bertazzo, Sergio, Schurgers, Leon J, Shanahan, Catherine M
Published in Circulation research (10.04.2015)
Published in Circulation research (10.04.2015)
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Journal Article
Reduced Vitamin K Status as a Potentially Modifiable Risk Factor of Severe Coronavirus Disease 2019
Dofferhoff, Anton S M, Piscaer, Ianthe, Schurgers, Leon J, Visser, Margot P J, van den Ouweland, Jody M W, de Jong, Pim A, Gosens, Reinoud, Hackeng, Tilman M, van Daal, Henny, Lux, Petra, Maassen, Cecile, Karssemeijer, Esther G A, Vermeer, Cees, Wouters, Emiel F M, Kistemaker, Loes E M, Walk, Jona, Janssen, Rob
Published in Clinical infectious diseases (06.12.2021)
Published in Clinical infectious diseases (06.12.2021)
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Journal Article
Matrix Gla-protein: the calcification inhibitor in need of vitamin K
Schurgers, Leon J, Cranenburg, Ellen C M, Vermeer, Cees
Published in Thrombosis and haemostasis (01.10.2008)
Published in Thrombosis and haemostasis (01.10.2008)
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Journal Article
Calcium Regulates Key Components of Vascular Smooth Muscle Cell–Derived Matrix Vesicles to Enhance Mineralization
Kapustin, Alexander N, Davies, John D, Reynolds, Joanne L, McNair, Rosamund, Jones, Gregory T, Sidibe, Anissa, Schurgers, Leon J, Skepper, Jeremy N, Proudfoot, Diane, Mayr, Manuel, Shanahan, Catherine M
Published in Circulation research (24.06.2011)
Published in Circulation research (24.06.2011)
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Journal Article
Prothrombin Loading of Vascular Smooth Muscle Cell–Derived Exosomes Regulates Coagulation and Calcification
Kapustin, Alexander N, Schoppet, Michael, Schurgers, Leon J, Reynolds, Joanne L, McNair, Rosamund, Heiss, Alexander, Jahnen-Dechent, Willi, Hackeng, Tilman M, Schlieper, Georg, Harrison, Paul, Shanahan, Catherine M
Published in Arteriosclerosis, thrombosis, and vascular biology (01.03.2017)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.03.2017)
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Journal Article
Apolipoprotein E Regulates Amyloid Formation within Endosomes of Pigment Cells
van Niel, Guillaume, Bergam, Ptissam, Di Cicco, Aurelie, Hurbain, Ilse, Lo Cicero, Alessandra, Dingli, Florent, Palmulli, Roberta, Fort, Cecile, Potier, Marie Claude, Schurgers, Leon J., Loew, Damarys, Levy, Daniel, Raposo, Graça
Published in Cell reports (Cambridge) (06.10.2015)
Published in Cell reports (Cambridge) (06.10.2015)
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Journal Article
Chronic Mineral Dysregulation Promotes Vascular Smooth Muscle Cell Adaptation and Extracellular Matrix Calcification
SHROFF, Rukshana C, MCNAIR, Rosamund, SKEPPER, Jeremy N, FIGG, Nichola, SCHURGERS, Leon J, DEANFIELD, John, REES, Lesley, SHANAHAN, Catherine M
Published in Journal of the American Society of Nephrology (2010)
Published in Journal of the American Society of Nephrology (2010)
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Journal Article
Calcium Signalling in Heart and Vessels: Role of Calmodulin and Downstream Calmodulin-Dependent Protein Kinases
Beghi, Sofia, Furmanik, Malgorzata, Jaminon, Armand, Veltrop, Rogier, Rapp, Nikolas, Wichapong, Kanin, Bidar, Elham, Buschini, Annamaria, Schurgers, Leon J
Published in International journal of molecular sciences (17.12.2022)
Published in International journal of molecular sciences (17.12.2022)
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Journal Article
Matrix Gla protein is an independent predictor of both intimal and medial vascular calcification in chronic kidney disease
Jaminon, Armand M. G., Dai, Lu, Qureshi, Abdul Rashid, Evenepoel, Pieter, Ripsweden, Jonaz, Söderberg, Magnus, Witasp, Anna, Olauson, Hannes, Schurgers, Leon J., Stenvinkel, Peter
Published in Scientific reports (20.04.2020)
Published in Scientific reports (20.04.2020)
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Journal Article
Vitamin K-antagonists accelerate atherosclerotic calcification and induce a vulnerable plaque phenotype
Schurgers, Leon J, Joosen, Ivo A, Laufer, Eduard M, Chatrou, Martijn L L, Herfs, Marjolein, Winkens, Mark H M, Westenfeld, Ralf, Veulemans, Verena, Krueger, Thilo, Shanahan, Catherine M, Jahnen-Dechent, Willi, Biessen, Erik, Narula, Jagat, Vermeer, Cees, Hofstra, Leonard, Reutelingsperger, Chris P
Published in PloS one (29.08.2012)
Published in PloS one (29.08.2012)
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Journal Article
Differential Effects of Platelet Factor 4 (CXCL4) and Its Non-Allelic Variant (CXCL4L1) on Cultured Human Vascular Smooth Muscle Cells
Kaczor, Dawid M, Kramann, Rafael, Hackeng, Tilman M, Schurgers, Leon J, Koenen, Rory R
Published in International journal of molecular sciences (06.01.2022)
Published in International journal of molecular sciences (06.01.2022)
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Journal Article
The Circulating Inactive Form of Matrix Gla Protein Is a Surrogate Marker for Vascular Calcification in Chronic Kidney Disease: A Preliminary Report
Schurgers, Leon J, Barreto, Daniela V, Barreto, Fellype C, Liabeuf, Sophie, Renard, Cedric, Magdeleyns, Elke J, Vermeer, Cees, Choukroun, Gabriel, Massy, Ziad A
Published in Clinical journal of the American Society of Nephrology (01.04.2010)
Published in Clinical journal of the American Society of Nephrology (01.04.2010)
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Journal Article
Vitamin K intake and status are low in hemodialysis patients
Cranenburg, Ellen C.M., Schurgers, Leon J., Uiterwijk, Herma H., Beulens, Joline W.J., Dalmeijer, Gerdien W., Westerhuis, Ralf, Magdeleyns, Elke J., Herfs, Marjolein, Vermeer, Cees, Laverman, Gozewijn D.
Published in Kidney international (01.09.2012)
Published in Kidney international (01.09.2012)
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Journal Article
Pharmacological and Nutritional Modulation of Vascular Calcification
Vossen, Liv M, Kroon, Abraham A, Schurgers, Leon J, de Leeuw, Peter W
Published in Nutrients (30.12.2019)
Published in Nutrients (30.12.2019)
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Journal Article
Intimal and medial calcification in relation to cardiovascular risk factors
Zwakenberg, Sabine R, de Jong, Pim A, Hendriks, Eva J, Westerink, Jan, Spiering, Wilko, de Borst, Gert J, Cramer, Maarten J, Bartstra, Jonas W, Doesburg, Teddo, Rutters, Femke, van der Heijden, Amber A, Schalkwijk, Casper, Schurgers, Leon J, van der Schouw, Yvonne T, Beulens, Joline W. J
Published in PloS one (13.07.2020)
Published in PloS one (13.07.2020)
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Journal Article
VItamin K In PEritonial DIAlysis (VIKIPEDIA): Rationale and study protocol for a randomized controlled trial
Roumeliotis, Stefanos, Roumeliotis, Athanasios, Georgianos, Panagiotis I, Thodis, Elias, Schurgers, Leon J, Maresz, Katarzyna, Eleftheriadis, Theodoros, Dounousi, Evangelia, Tripepi, Giovanni, Mallamaci, Francesca, Liakopoulos, Vassilios
Published in PloS one (17.08.2022)
Published in PloS one (17.08.2022)
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