Reversal of Dabigatran-induced Bleeding by Coagulation Factor Concentrates in a Rat-tail Bleeding Model and Lack of Effect on Assays of Coagulation
van Ryn, Joanne, Schurer, Johanna, Kink-Eiband, Monika, Clemens, Andreas
Published in Anesthesiology (Philadelphia) (01.06.2014)
Published in Anesthesiology (Philadelphia) (01.06.2014)
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Reversal of Trauma-Induced Bleeding and Anticoagulation with a Dabigatran-Specific Antidote (idarucizumab) As Assessed By Shed and Washed Blood Tests in a Pig Model of Supratherapeutic Anticoagulation and Trauma
Grottke, Oliver, Honickel, Markus, Schurer, Johanna, van Ryn, Joanne
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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The Successful Reversal of Dabigatran-Induced Bleeding by Coagulation Factor Concentrates in a Rat Tail Bleeding Model Do Not Correlate with Ex Vivo Markers of Anticoagulation
van Ryn, Joanne, Schurer, Johanna, Kink-Eiband, Monika, Clemens, Andreas
Published in Blood (18.11.2011)
Published in Blood (18.11.2011)
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EVALUATION OF A SPECIFIC ANTIDOTE TO DABIGATRAN: IN VITRO PROPERTIES, PHARMACOKINETICS AND REVERSAL OF DABIGATRAN ETEXILATE–INDUCED BLEEDING IN RATS
van Ryn, Joanne, Litzenburger, Tobias, Gan, Guanfa, Coble, Kelly, Schurer, Johanna
Published in Journal of the American College of Cardiology (12.03.2013)
Published in Journal of the American College of Cardiology (12.03.2013)
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DIFFERENTIAL EFFECTS OF DABIGATRAN ETEXILATE AND TICAGRELOR ON BLEEDING AS ASSESSED BY WASHED BLOOD AND SHED BLOOD TESTS IN HEALTHY SUBJECTS
van Ryn, Joanne, Giessmann, Thomas, Gouya, Ghazaleh, Wolzt, Michael, Schurer, Johanna, Lobmeyer, Maximilian, Brueckmann, Martina
Published in Journal of the American College of Cardiology (12.03.2013)
Published in Journal of the American College of Cardiology (12.03.2013)
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Abstract WP261: In Vitro Characterization, Pharmacokinetics and Reversal of Supratherapeutic Doses of Dabigatran-Induced Bleeding in Rats by a Specific Antibody Fragment Antidote to Dabigatran
van Ryn, Joanne, Litzenburger, Tobias, Gan, Guanfa, Coble, Kelly, Schurer, Johanna
Published in Stroke (1970) (01.02.2013)
Published in Stroke (1970) (01.02.2013)
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Abstract WP269: Increased Sensitivity to recombinant Tissue Plasminogen Activator (rtPA)-induced Lysis in vitro of Thrombi Produced in Human Platelet Rich Plasma containing Dabigatran
van Ryn, Joanne, Kink-Eiband, Monika, Fischer, Davina, Schurer, Johanna, Clemens, Andreas
Published in Stroke (1970) (01.02.2013)
Published in Stroke (1970) (01.02.2013)
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Journal Article
In Vitro Characterization, Pharmacokinetics and Reversal of Supratherapeutic Doses of Dabigatran-Induced Bleeding in Rats by a Specific Antibody Fragment Antidote to Dabigatran
van Ryn, Joanne, Litzenburger, Tobias, Gan, Guanfa, Coble, Kelly, Schurer, Johanna
Published in Blood (16.11.2012)
Published in Blood (16.11.2012)
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Journal Article
EVALUATION OF A SPECIFIC ANTIDOTE TO DABIGATRAN: IN VITRO PROPERTIES, PHARMACOKINETICS AND REVERSAL OF DABIGATRAN ETEXILATE–INDUCED BLEEDING IN RATS
van Ryn, Joanne, Litzenburger, Tobias, Gan, Guanfa, Coble, Kelly, Schurer, Johanna
Published in Journal of the American College of Cardiology (12.03.2013)
Published in Journal of the American College of Cardiology (12.03.2013)
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Journal Article