Class effects of SGLT2 inhibitors in mouse cardiomyocytes and hearts: inhibition of Na+/H+ exchanger, lowering of cytosolic Na+ and vasodilation
Uthman, Laween, Baartscheer, Antonius, Bleijlevens, Boris, Schumacher, Cees A., Fiolet, Jan W. T., Koeman, Anneke, Jancev, Milena, Hollmann, Markus W., Weber, Nina C., Coronel, Ruben, Zuurbier, Coert J.
Published in Diabetologia (01.03.2018)
Published in Diabetologia (01.03.2018)
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Journal Article
Empagliflozin decreases myocardial cytoplasmic Na+ through inhibition of the cardiac Na+/H+ exchanger in rats and rabbits
Baartscheer, Antonius, Schumacher, Cees A., Wüst, Rob C. I., Fiolet, Jan W. T., Stienen, Ger J. M., Coronel, Ruben, Zuurbier, Coert J.
Published in Diabetologia (01.03.2017)
Published in Diabetologia (01.03.2017)
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Journal Article
Empagliflozin reduces oxidative stress through inhibition of the novel inflammation/NHE/[Na+]c/ROS-pathway in human endothelial cells
Uthman, Laween, Li, Xiaoling, Baartscheer, Antonius, Schumacher, Cees A., Baumgart, Patricia, Hermanides, Jeroen, Preckel, Benedikt, Hollmann, Markus W., Coronel, Ruben, Zuurbier, Coert J., Weber, Nina C.
Published in Biomedicine & pharmacotherapy (01.02.2022)
Published in Biomedicine & pharmacotherapy (01.02.2022)
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Journal Article
Direct Cardiac Actions of Sodium Glucose Cotransporter 2 Inhibitors Target Pathogenic Mechanisms Underlying Heart Failure in Diabetic Patients
Uthman, Laween, Baartscheer, Antonius, Schumacher, Cees A, Fiolet, Jan W T, Kuschma, Marius C, Hollmann, Markus W, Coronel, Ruben, Weber, Nina C, Zuurbier, Coert J
Published in Frontiers in physiology (21.11.2018)
Published in Frontiers in physiology (21.11.2018)
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Journal Article
RBM20 Mutations Induce an Arrhythmogenic Dilated Cardiomyopathy Related to Disturbed Calcium Handling
van den Hoogenhof, Maarten M.G, Beqqali, Abdelaziz, Amin, Ahmad S, van der Made, Ingeborg, Aufiero, Simona, Khan, Mohsin A.F, Schumacher, Cees A, Jansweijer, Joeri A, van Spaendonck-Zwarts, Karin Y, Remme, Carol Ann, Backs, Johannes, Verkerk, Arie O, Baartscheer, Antonius, Pinto, Yigal M, Creemers, Esther E
Published in Circulation (New York, N.Y.) (25.09.2018)
Published in Circulation (New York, N.Y.) (25.09.2018)
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Journal Article
Sodium-glucose co-transporter 2 inhibitor empagliflozin inhibits the cardiac Na+/H+ exchanger 1: persistent inhibition under various experimental conditions
Zuurbier, Coert J, Baartscheer, Antonius, Schumacher, Cees A, Fiolet, Jan W T, Coronel, Ruben
Published in Cardiovascular research (17.12.2021)
Published in Cardiovascular research (17.12.2021)
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Journal Article
Functional NaV1.8 Channels in Intracardiac Neurons: The Link Between SCN10A and Cardiac Electrophysiology
Verkerk, Arie O, Remme, Carol Ann, Schumacher, Cees A, Scicluna, Brendon P, Wolswinkel, Rianne, de Jonge, Berend, Bezzina, Connie R, Veldkamp, Marieke W
Published in Circulation research (20.07.2012)
Published in Circulation research (20.07.2012)
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Journal Article
Protease XIV abolishes NHE inhibition by empagliflozin in cardiac cells
Chen, Sha, Schumacher, Cees A, Van Amersfoorth, Shirley C M, Fiolet, Jan W T, Baartscheer, Antonius, Veldkamp, Marieke W, Coronel, Ruben, Zuurbier, Coert J
Published in Frontiers in physiology (26.07.2023)
Published in Frontiers in physiology (26.07.2023)
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Journal Article
Dyscholesterolemia Protects Against Ischemia-Induced Ventricular Arrhythmias
Baartscheer, Antonius, Schumacher, Cees A, Wekker, Vincent, Verkerk, Arie O, Veldkamp, Marieke W, van Oort, Ralph J, Elzenaar, Ies, Ottenhoff, Roelof, van Roomen, Cindy, Aerts, Hans, Coronel, Ruben
Published in Circulation. Arrhythmia and electrophysiology (01.12.2015)
Published in Circulation. Arrhythmia and electrophysiology (01.12.2015)
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In vivo mouse myocardial (31)P MRS using three-dimensional image-selected in vivo spectroscopy (3D ISIS): technical considerations and biochemical validations
Bakermans, Adrianus J, Abdurrachim, Desiree, van Nierop, Bastiaan J, Koeman, Anneke, van der Kroon, Inge, Baartscheer, Antonius, Schumacher, Cees A, Strijkers, Gustav J, Houten, Sander M, Zuurbier, Coert J, Nicolay, Klaas, Prompers, Jeanine J
Published in NMR in biomedicine (01.10.2015)
Published in NMR in biomedicine (01.10.2015)
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Journal Article
Orphan nuclear receptor Nur77 affects cardiomyocyte calcium homeostasis and adverse cardiac remodelling
Medzikovic, Lejla, Schumacher, Cees A., Verkerk, Arie O., van Deel, Elza D., Wolswinkel, Rianne, van der Made, Ingeborg, Bleeker, Natascha, Cakici, Daniella, van den Hoogenhof, Maarten M. G., Meggouh, Farid, Creemers, Esther E., Remme, Carol Ann, Baartscheer, Antonius, de Winter, Robbert J., de Vries, Carlie J. M., Arkenbout, E. Karin, de Waard, Vivian
Published in Scientific reports (21.10.2015)
Published in Scientific reports (21.10.2015)
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Journal Article
Neurokinin-3 receptor activation selectively prolongs atrial refractoriness by inhibition of a background K+ channel
Veldkamp, Marieke W., Geuzebroek, Guillaume S. C., Baartscheer, Antonius, Verkerk, Arie O., Schumacher, Cees A., Suarez, Gedeon G., Berger, Wouter R., Casini, Simona, van Amersfoorth, Shirley C. M., Scholman, Koen T., Driessen, Antoine H. G., Belterman, Charly N. W., van Ginneken, Antoni C. G., de Groot, Joris R., de Bakker, Jacques M. T., Remme, Carol Ann, Boukens, Bas J., Coronel, Ruben
Published in Nature communications (19.10.2018)
Published in Nature communications (19.10.2018)
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Journal Article
Mitochondrial oxygen tension within the heart
Mik, Egbert G, Ince, Can, Eerbeek, Otto, Heinen, Andre, Stap, Jan, Hooibrink, Berend, Schumacher, Cees A, Balestra, Gianmarco M, Johannes, Tanja, Beek, Johan F, Nieuwenhuis, Ab F, van Horssen, Pepijn, Spaan, Jos A, Zuurbier, Coert J
Published in Journal of molecular and cellular cardiology (01.06.2009)
Published in Journal of molecular and cellular cardiology (01.06.2009)
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Reducing mitochondrial bound hexokinase II mediates transition from non-injurious into injurious ischemia/reperfusion of the intact heart
Nederlof, Rianne, Gürel-Gurevin, Ebru, Eerbeek, Otto, Xie, Chaoqin, Deijs, G. Sjoerd, Konkel, Moritz, Hu, Jun, Weber, Nina C., Schumacher, Cees A., Baartscheer, Antonius, Mik, Egbert G., Hollmann, Markus W., Akar, Fadi G., Zuurbier, Coert J.
Published in Journal of physiology and biochemistry (01.08.2016)
Published in Journal of physiology and biochemistry (01.08.2016)
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Transmural dispersion of refractoriness and conduction velocity is associated with heterogeneously reduced connexin43 in a rabbit model of heart failure
Wiegerinck, Rob F, van Veen, Toon A B, Belterman, Charly N, Schumacher, Cees A, Noorman, Maartje, de Bakker, Jacques M T, Coronel, Ruben
Published in Heart rhythm (01.08.2008)
Published in Heart rhythm (01.08.2008)
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Journal Article
Acute Administration of Fish Oil Inhibits Triggered Activity in Isolated Myocytes From Rabbits and Patients With Heart Failure
DEN RUIJTER, Hester M, BERECKI, Géza, CORONEL, Ruben, VERKERK, Arie O, BAKKER, Diane, BAARTSCHEER, Antonius, SCHUMACHER, Cees A, BELTERMAN, Charly N. W, DE JONGE, Nicolaas, FIOLET, Jan W. T, BROUWER, Ingeborg A
Published in Circulation (New York, N.Y.) (29.01.2008)
Published in Circulation (New York, N.Y.) (29.01.2008)
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Journal Article
In vivo mouse myocardial 31P MRS using three-dimensional image-selected in vivo spectroscopy (3D ISIS): technical considerations and biochemical validations
Bakermans, Adrianus J., Abdurrachim, Desiree, van Nierop, Bastiaan J., Koeman, Anneke, van der Kroon, Inge, Baartscheer, Antonius, Schumacher, Cees A., Strijkers, Gustav J., Houten, Sander M., Zuurbier, Coert J., Nicolay, Klaas, Prompers, Jeanine J.
Published in NMR in biomedicine (01.10.2015)
Published in NMR in biomedicine (01.10.2015)
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Journal Article
Chronic inhibition of Na+/H+-exchanger attenuates cardiac hypertrophy and prevents cellular remodeling in heart failure
BAARTSCHEER, Antonius, SCHUMACHER, Cees A, VAN BORREN, Marcel M. G. J, BELTERMAN, Charly N. W, CORONEL, Ruben, OPTHOF, Tobias, FIOLET, Jan W. T
Published in Cardiovascular research (2005)
Published in Cardiovascular research (2005)
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Incorporated sarcolemmal fish oil fatty acids shorten pig ventricular action potentials
VERKERK, Arie O, VAN GINNEKEN, Antoni C. G, FIOLET, Jan W. T, ZOCK, Peter L, CORONEL, Ruben, BERECKI, Géza, DEN RUIJTER, Hester M, SCHUMACHER, Cees A, VELDKAMP, Marieke W, BAARTSCHEER, Antonius, CASINI, Simona, OPTHOF, Tobias, HOVENIER, Robert
Published in Cardiovascular research (01.06.2006)
Published in Cardiovascular research (01.06.2006)
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Journal Article
The Driving Force of the Na/Ca-Exchanger during Metabolic Inhibition
Baartscheer, Antonius, Schumacher, Cees A, Coronel, Ruben, Fiolet, Jan W T
Published in Frontiers in physiology (2011)
Published in Frontiers in physiology (2011)
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