Differential effect of troglitazone on the human bile acid transporters, MRP2 and BSEP, in the PXB hepatic chimeric mouse
Foster, John R, Jacobsen, Matt, Kenna, Gerry, Schulz-Utermoehl, Timothy, Morikawa, Yoshio, Salmu, Juuso, Wilson, Ian D
Published in Toxicologic pathology (01.12.2012)
Published in Toxicologic pathology (01.12.2012)
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Application of HepG2/C3A liver spheroids as a model system for genotoxicity studies
Coltman, Nicholas J., Coke, Brandon A., Chatzi, Kyriaki, Shepherd, Emma L., Lalor, Patricia F., Schulz-Utermoehl, Timothy, Hodges, Nikolas J.
Published in Toxicology letters (01.07.2021)
Published in Toxicology letters (01.07.2021)
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Azetidines Kill Multidrug-Resistant Mycobacterium tuberculosis without Detectable Resistance by Blocking Mycolate Assembly
Cui, Yixin, Lanne, Alice, Peng, Xudan, Browne, Edward, Bhatt, Apoorva, Coltman, Nicholas J., Craven, Philip, Cox, Liam R., Cundy, Nicholas J., Dale, Katie, Feula, Antonio, Frampton, Jon, Fung, Martin, Morton, Michael, Goff, Aaron, Salih, Mariwan, Lang, Xingfen, Li, Xingjian, Moon, Chris, Pascoe, Jordan, Portman, Vanessa, Press, Cara, Schulz-Utermoehl, Timothy, Lee, Suki, Tortorella, Micky D., Tu, Zhengchao, Underwood, Zoe E., Wang, Changwei, Yoshizawa, Akina, Zhang, Tianyu, Waddell, Simon J., Bacon, Joanna, Alderwick, Luke, Fossey, John S., Neagoie, Cleopatra
Published in Journal of medicinal chemistry (22.02.2024)
Published in Journal of medicinal chemistry (22.02.2024)
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Diclofenac metabolism in the mouse: Novel in vivo metabolites identified by high performance liquid chromatography coupled to linear ion trap mass spectrometry
Sarda, Sunil, Page, Chris, Pickup, Kathryn, Schulz-Utermoehl, Timothy, Wilson, Ian
Published in Xenobiotica (01.02.2012)
Published in Xenobiotica (01.02.2012)
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In vitro models of xenobiotic metabolism in trout for use in environmental bioaccumulation studies
Uchea, Chibuzor, Sarda, Sunil, Schulz-Utermoehl, Timothy, Owen, Stewart, Chipman, Kevin J.
Published in Xenobiotica (01.05.2013)
Published in Xenobiotica (01.05.2013)
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Derivatisation of parthenolide to address chemoresistant chronic lymphocytic leukaemia
Li, Xingjian, Payne, Daniel T, Ampolu, Badarinath, Bland, Nicholas, Brown, Jane T, Dutton, Mark J, Fitton, Catherine A, Gulliver, Abigail, Hale, Lee, Hamza, Daniel, Jones, Geraint, Lane, Rebecca, Leach, Andrew G, Male, Louise, Merisor, Elena G, Morton, Michael J, Quy, Alex S, Roberts, Ruth, Scarll, Rosanna, Schulz-Utermoehl, Timothy, Stankovic, Tatjana, Stevenson, Brett, Fossey, John S, Agathanggelou, Angelo
Published in MedChemComm (01.08.2019)
Published in MedChemComm (01.08.2019)
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Evaluation of the pharmacokinetics, biotransformation and hepatic transporter effects of troglitazone in mice with humanized livers
Schulz-Utermoehl, Timothy, Sarda, Sunil, Foster, John R., Jacobsen, Matt, Kenna, J. Gerry, Morikawa, Yoshio, Salmu, Juuso, Gross, Gerhard, Wilson, Ian D.
Published in Xenobiotica (01.06.2012)
Published in Xenobiotica (01.06.2012)
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Assessment of P450 induction in the marmoset monkey using targeted anti-peptide antibodies
Schulz, Thomas G, Thiel, Renate, Neubert, Diether, Brassil, Patrick J, Schulz-Utermoehl, Timothy, Boobis, Alan R, Edwards, Robert J
Published in Biochimica et biophysica acta (09.03.2001)
Published in Biochimica et biophysica acta (09.03.2001)
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Pharmacokinetics and metabolism of midazolam in chimeric mice with humanised livers
Samuelsson, Kristin, Pickup, Kathryn, Sarda, Sunil, Swales, John G., Morikawa, Yoshio, Schulz-Utermoehl, Timothy, Hutchison, Michael, Wilson, Ian D.
Published in Xenobiotica (01.11.2012)
Published in Xenobiotica (01.11.2012)
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Derivatisation of parthenolide to address chemoresistant chronic lymphocytic leukaemia† †Electronic supplementary information (ESI) available: General experimental details, aspects relating to cultivation of feverfew, the PTL extraction protocol, synthesis, biological assays computational information and spectrums are detailed in the supporting information. Methods described and references cited therein,45 should be referred to in regard of the docking, crystallographic, synthetic and toxicologi
Li, Xingjian, Payne, Daniel T., Ampolu, Badarinath, Bland, Nicholas, Brown, Jane T., Dutton, Mark J., Fitton, Catherine A., Gulliver, Abigail, Hale, Lee, Hamza, Daniel, Jones, Geraint, Lane, Rebecca, Leach, Andrew G., Male, Louise, Merisor, Elena G., Morton, Michael J., Quy, Alex S., Roberts, Ruth, Scarll, Rosanna, Schulz-Utermoehl, Timothy, Stankovic, Tatjana, Stevenson, Brett, Fossey, John S., Agathanggelou, Angelo
Published in MedChemComm (01.08.2019)
Published in MedChemComm (01.08.2019)
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In vitro exploration of potential mechanisms of toxicity of the human hepatotoxic drug fenclozic acid
Rodrigues, Alison V. M., Rollison, Helen E., Martin, Scott, Sarda, Sunil, Schulz-Utermoehl, Timothy, Stahl, Simone, Gustafsson, Frida, Eakins, Julie, Kenna, J. Gerry, Wilson, Ian D.
Published in Archives of toxicology (01.08.2013)
Published in Archives of toxicology (01.08.2013)
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The hepatic reductase null mouse as a model for exploring hepatic conjugation of xenobiotics: Application to the metabolism of diclofenac
Pickup, Kathryn, Gavin, Alex, Jones, Huw B., Karlsson, Elin, Page, Chris, Ratcliffe, Kerry, Sarda, Sunil, Schulz-Utermoehl, Timothy, Wilson, Ian
Published in Xenobiotica (01.02.2012)
Published in Xenobiotica (01.02.2012)
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In Vitro Hepatic Metabolism of Cediranib, a Potent Vascular Endothelial Growth Factor Tyrosine Kinase Inhibitor: Interspecies Comparison and Human Enzymology
SCHULZ-UTERMOEHL, Timothy, SPEAR, Michael, POLLARD, Christopher R. J, PATTISON, Christine, ROLLISON, Helen, SARDA, Sunil, WARD, Michelle, BUSHBY, Nick, JORDAN, Angela, HARRISON, Mike
Published in Drug metabolism and disposition (01.10.2010)
Published in Drug metabolism and disposition (01.10.2010)
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Characterisation and identification of the human N +-glucuronide metabolite of cediranib
Lenz, Eva M., Spear, Michael, Drake, C., Pollard, Christopher R.J., Ward, Michelle, Schulz-Utermoehl, Timothy, Harrison, Mike
Published in Journal of pharmaceutical and biomedical analysis (02.11.2010)
Published in Journal of pharmaceutical and biomedical analysis (02.11.2010)
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Characterisation and identification of the human N super(+)-glucuronide metabolite of cediranib
Lenz, Eva M, Spear, Michael, Drake, C, Pollard, Christopher RJ, Ward, Michelle, Schulz-Utermoehl, Timothy, Harrison, Mike
Published in Journal of pharmaceutical and biomedical analysis (02.11.2010)
Published in Journal of pharmaceutical and biomedical analysis (02.11.2010)
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