Mutual exclusivity analysis identifies oncogenic network modules
Ciriello, Giovanni, Cerami, Ethan, Sander, Chris, Schultz, Nikolaus
Published in Genome research (01.02.2012)
Published in Genome research (01.02.2012)
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Genome-wide analysis of noncoding regulatory mutations in cancer
Weinhold, Nils, Jacobsen, Anders, Schultz, Nikolaus, Sander, Chris, Lee, William
Published in Nature genetics (01.11.2014)
Published in Nature genetics (01.11.2014)
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Emerging landscape of oncogenic signatures across human cancers
Ciriello, Giovanni, Miller, Martin L, Aksoy, Bülent Arman, Senbabaoglu, Yasin, Schultz, Nikolaus, Sander, Chris
Published in Nature genetics (01.10.2013)
Published in Nature genetics (01.10.2013)
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The expanding landscape of 'oncohistone' mutations in human cancers
Nacev, Benjamin A, Feng, Lijuan, Bagert, John D, Lemiesz, Agata E, Gao, JianJiong, Soshnev, Alexey A, Kundra, Ritika, Schultz, Nikolaus, Muir, Tom W, Allis, C David
Published in Nature (London) (01.03.2019)
Published in Nature (London) (01.03.2019)
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Genomic correlates of clinical outcome in advanced prostate cancer
Abida, Wassim, Cyrta, Joanna, Heller, Glenn, Prandi, Davide, Armenia, Joshua, Coleman, Ilsa, Cieslik, Marcin, Benelli, Matteo, Robinson, Dan, Van Allen, Eliezer M., Sboner, Andrea, Fedrizzi, Tarcisio, Mosquera, Juan Miguel, Robinson, Brian D., De Sarkar, Navonil, Kunju, Lakshmi P., Tomlins, Scott, Wu, Yi Mi, Rodrigues, Daniel Nava, Loda, Massimo, Gopalan, Anuradha, Reuter, Victor E., Pritchard, Colin C., Mateo, Joaquin, Bianchini, Diletta, Miranda, Susana, Carreira, Suzanne, Rescigno, Pasquale, Filipenko, Julie, Vinson, Jacob, Montgomery, Robert B., Beltran, Himisha, Heath, Elisabeth I., Scher, Howard I., Kantoff, Philip W., Taplin, Mary-Ellen, Schultz, Nikolaus, deBono, Johann S., Demichelis, Francesca, Nelson, Peter S., Rubin, Mark A., Chinnaiyan, Arul M., Sawyers, Charles L.
Published in Proceedings of the National Academy of Sciences - PNAS (04.06.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (04.06.2019)
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Genomic and transcriptomic hallmarks of poorly differentiated and anaplastic thyroid cancers
Landa, Iñigo, Ibrahimpasic, Tihana, Boucai, Laura, Sinha, Rileen, Knauf, Jeffrey A, Shah, Ronak H, Dogan, Snjezana, Ricarte-Filho, Julio C, Krishnamoorthy, Gnana P, Xu, Bin, Schultz, Nikolaus, Berger, Michael F, Sander, Chris, Taylor, Barry S, Ghossein, Ronald, Ganly, Ian, Fagin, James A
Published in The Journal of clinical investigation (01.03.2016)
Published in The Journal of clinical investigation (01.03.2016)
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Loss of the FAT1 Tumor Suppressor Promotes Resistance to CDK4/6 Inhibitors via the Hippo Pathway
Li, Zhiqiang, Razavi, Pedram, Li, Qing, Toy, Weiyi, Liu, Bo, Ping, Christina, Hsieh, Wilson, Sanchez-Vega, Francisco, Brown, David N., Da Cruz Paula, Arnaud F., Morris, Luc, Selenica, Pier, Eichenberger, Emily, Shen, Ronglai, Schultz, Nikolaus, Rosen, Neal, Scaltriti, Maurizio, Brogi, Edi, Baselga, Jose, Reis-Filho, Jorge S., Chandarlapaty, Sarat
Published in Cancer cell (10.12.2018)
Published in Cancer cell (10.12.2018)
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The long tail of oncogenic drivers in prostate cancer
Armenia, Joshua, Wankowicz, Stephanie A M, Liu, David, Gao, Jianjiong, Kundra, Ritika, Reznik, Ed, Chatila, Walid K, Chakravarty, Debyani, Han, G Celine, Coleman, Ilsa, Montgomery, Bruce, Pritchard, Colin, Morrissey, Colm, Barbieri, Christopher E, Beltran, Himisha, Sboner, Andrea, Zafeiriou, Zafeiris, Miranda, Susana, Bielski, Craig M, Penson, Alexander V, Tolonen, Charlotte, Huang, Franklin W, Robinson, Dan, Wu, Yi Mi, Lonigro, Robert, Garraway, Levi A, Demichelis, Francesca, Kantoff, Philip W, Taplin, Mary-Ellen, Abida, Wassim, Taylor, Barry S, Scher, Howard I, Nelson, Peter S, de Bono, Johann S, Rubin, Mark A, Sawyers, Charles L, Chinnaiyan, Arul M, Schultz, Nikolaus, Van Allen, Eliezer M
Published in Nature genetics (01.05.2018)
Published in Nature genetics (01.05.2018)
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Prospective Genotyping of Hepatocellular Carcinoma: Clinical Implications of Next-Generation Sequencing for Matching Patients to Targeted and Immune Therapies
Harding, James J, Nandakumar, Subhiksha, Armenia, Joshua, Khalil, Danny N, Albano, Melanie, Ly, Michele, Shia, Jinru, Hechtman, Jaclyn F, Kundra, Ritika, El Dika, Imane, Do, Richard K, Sun, Yichao, Kingham, T Peter, D'Angelica, Michael I, Berger, Michael F, Hyman, David M, Jarnagin, William, Klimstra, David S, Janjigian, Yelena Y, Solit, David B, Schultz, Nikolaus, Abou-Alfa, Ghassan K
Published in Clinical cancer research (01.04.2019)
Published in Clinical cancer research (01.04.2019)
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Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity
Chang, Matthew T, Asthana, Saurabh, Gao, Sizhi Paul, Lee, Byron H, Chapman, Jocelyn S, Kandoth, Cyriac, Gao, JianJiong, Socci, Nicholas D, Solit, David B, Olshen, Adam B, Schultz, Nikolaus, Taylor, Barry S
Published in Nature biotechnology (01.02.2016)
Published in Nature biotechnology (01.02.2016)
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Comprehensive Molecular Profiling of Intrahepatic and Extrahepatic Cholangiocarcinomas: Potential Targets for Intervention
Lowery, Maeve A, Ptashkin, Ryan, Jordan, Emmet, Berger, Michael F, Zehir, Ahmet, Capanu, Marinela, Kemeny, Nancy E, O'Reilly, Eileen M, El-Dika, Imane, Jarnagin, William R, Harding, James J, D'Angelica, Michael I, Cercek, Andrea, Hechtman, Jaclyn F, Solit, David B, Schultz, Nikolaus, Hyman, David M, Klimstra, David S, Saltz, Leonard B, Abou-Alfa, Ghassan K
Published in Clinical cancer research (01.09.2018)
Published in Clinical cancer research (01.09.2018)
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The Genomic Landscape of Endocrine-Resistant Advanced Breast Cancers
Razavi, Pedram, Chang, Matthew T., Xu, Guotai, Bandlamudi, Chaitanya, Ross, Dara S., Vasan, Neil, Cai, Yanyan, Bielski, Craig M., Donoghue, Mark T.A., Jonsson, Philip, Penson, Alexander, Shen, Ronglai, Pareja, Fresia, Kundra, Ritika, Middha, Sumit, Cheng, Michael L., Zehir, Ahmet, Kandoth, Cyriac, Patel, Ruchi, Huberman, Kety, Smyth, Lillian M., Jhaveri, Komal, Modi, Shanu, Traina, Tiffany A., Dang, Chau, Zhang, Wen, Weigelt, Britta, Li, Bob T., Ladanyi, Marc, Hyman, David M., Schultz, Nikolaus, Robson, Mark E., Hudis, Clifford, Brogi, Edi, Viale, Agnes, Norton, Larry, Dickler, Maura N., Berger, Michael F., Iacobuzio-Donahue, Christine A., Chandarlapaty, Sarat, Scaltriti, Maurizio, Reis-Filho, Jorge S., Solit, David B., Taylor, Barry S., Baselga, José
Published in Cancer cell (10.09.2018)
Published in Cancer cell (10.09.2018)
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Next-generation Sequencing of Nonmuscle Invasive Bladder Cancer Reveals Potential Biomarkers and Rational Therapeutic Targets
Pietzak, Eugene J, Bagrodia, Aditya, Cha, Eugene K, Drill, Esther N, Iyer, Gopa, Isharwal, Sumit, Ostrovnaya, Irina, Baez, Priscilla, Li, Qiang, Berger, Michael F, Zehir, Ahmet, Schultz, Nikolaus, Rosenberg, Jonathan E, Bajorin, Dean F, Dalbagni, Guido, Al-Ahmadie, Hikmat, Solit, David B, Bochner, Bernard H
Published in European urology (01.12.2017)
Published in European urology (01.12.2017)
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Clinical Sequencing Defines the Genomic Landscape of Metastatic Colorectal Cancer
Yaeger, Rona, Chatila, Walid K., Lipsyc, Marla D., Hechtman, Jaclyn F., Cercek, Andrea, Sanchez-Vega, Francisco, Jayakumaran, Gowtham, Middha, Sumit, Zehir, Ahmet, Donoghue, Mark T.A., You, Daoqi, Viale, Agnes, Kemeny, Nancy, Segal, Neil H., Stadler, Zsofia K., Varghese, Anna M., Kundra, Ritika, Gao, Jianjiong, Syed, Aijazuddin, Hyman, David M., Vakiani, Efsevia, Rosen, Neal, Taylor, Barry S., Ladanyi, Marc, Berger, Michael F., Solit, David B., Shia, Jinru, Saltz, Leonard, Schultz, Nikolaus
Published in Cancer cell (08.01.2018)
Published in Cancer cell (08.01.2018)
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Pattern discovery and cancer gene identification in integrated cancer genomic data
Mo, Qianxing, Wang, Sijian, Seshan, Venkatraman E., Olshen, Adam B., Schultz, Nikolaus, Sander, Chris, Powers, R. Scott, Ladanyi, Marc, Shen, Ronglai
Published in Proceedings of the National Academy of Sciences - PNAS (12.03.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (12.03.2013)
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First-line pembrolizumab and trastuzumab in HER2-positive oesophageal, gastric, or gastro-oesophageal junction cancer: an open-label, single-arm, phase 2 trial
Janjigian, Yelena Y, Maron, Steven B, Chatila, Walid K, Millang, Brittanie, Chavan, Shweta S, Alterman, Carly, Chou, Joanne F, Segal, Michal F, Simmons, Marc Z, Momtaz, Parisa, Shcherba, Marina, Ku, Geoffrey Y, Zervoudakis, Alice, Won, Elizabeth S, Kelsen, David P, Ilson, David H, Nagy, Rebecca J, Lanman, Richard B, Ptashkin, Ryan N, Donoghue, Mark T A, Capanu, Marinela, Taylor, Barry S, Solit, David B, Schultz, Nikolaus, Hechtman, Jaclyn F
Published in The lancet oncology (01.06.2020)
Published in The lancet oncology (01.06.2020)
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Comprehensive Molecular Characterization of Salivary Duct Carcinoma Reveals Actionable Targets and Similarity to Apocrine Breast Cancer
Dalin, Martin G, Desrichard, Alexis, Katabi, Nora, Makarov, Vladimir, Walsh, Logan A, Lee, Ken-Wing, Wang, Qingguo, Armenia, Joshua, West, Lyndsay, Dogan, Snjezana, Wang, Lu, Ramaswami, Deepa, Ho, Alan L, Ganly, Ian, Solit, David B, Berger, Michael F, Schultz, Nikolaus D, Reis-Filho, Jorge S, Chan, Timothy A, Morris, Luc G T
Published in Clinical cancer research (15.09.2016)
Published in Clinical cancer research (15.09.2016)
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Analysis of microRNA-target interactions across diverse cancer types
Jacobsen, Anders, Silber, Joachim, Harinath, Girish, Huse, Jason T, Schultz, Nikolaus, Sander, Chris
Published in Nature structural & molecular biology (01.11.2013)
Published in Nature structural & molecular biology (01.11.2013)
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Journal Article
Systematic identification of cancer driving signaling pathways based on mutual exclusivity of genomic alterations
Babur, Özgün, Gönen, Mithat, Aksoy, Bülent Arman, Schultz, Nikolaus, Ciriello, Giovanni, Sander, Chris, Demir, Emek
Published in Genome Biology (26.02.2015)
Published in Genome Biology (26.02.2015)
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Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal
Gao, Jianjiong, Aksoy, Bülent Arman, Dogrusoz, Ugur, Dresdner, Gideon, Gross, Benjamin, Sumer, S Onur, Sun, Yichao, Jacobsen, Anders, Sinha, Rileen, Larsson, Erik, Cerami, Ethan, Sander, Chris, Schultz, Nikolaus
Published in Science signaling (02.04.2013)
Published in Science signaling (02.04.2013)
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