Coordinate regulation of mutant NPC1 degradation by selective ER autophagy and MARCH6-dependent ERAD
Schultz, Mark L, Krus, Kelsey L, Kaushik, Susmita, Dang, Derek, Chopra, Ravi, Qi, Ling, Shakkottai, Vikram G, Cuervo, Ana Maria, Lieberman, Andrew P
Published in Nature communications (10.09.2018)
Published in Nature communications (10.09.2018)
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Journal Article
Enhanced Toll-like receptor (TLR) responses of TNFR-associated factor 3 (TRAF3)-deficient B lymphocytes
Xie, Ping, Poovassery, Jayakumar, Stunz, Laura L., Smith, Sonja M., Schultz, Mark L., Carlin, Lindsey E., Bishop, Gail A.
Published in Journal of leukocyte biology (01.12.2011)
Published in Journal of leukocyte biology (01.12.2011)
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Journal Article
Synthetic high-density lipoprotein nanoparticles for the treatment of Niemann-Pick diseases
Schultz, Mark L, Fawaz, Maria V, Azaria, Ruth D, Hollon, Todd C, Liu, Elaine A, Kunkel, Thaddeus J, Halseth, Troy A, Krus, Kelsey L, Ming, Ran, Morin, Emily E, McLoughlin, Hayley S, Bushart, David D, Paulson, Henry L, Shakkottai, Vikram G, Orringer, Daniel A, Schwendeman, Anna S, Lieberman, Andrew P
Published in BMC medicine (11.11.2019)
Published in BMC medicine (11.11.2019)
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Journal Article
CLN3 deficient cells display defects in the ARF1-Cdc42 pathway and actin-dependent events
Schultz, Mark L, Tecedor, Luis, Stein, Colleen S, Stamnes, Mark A, Davidson, Beverly L
Published in PloS one (02.05.2014)
Published in PloS one (02.05.2014)
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Journal Article
Species-specific differences in NPC1 protein trafficking govern therapeutic response in Niemann-Pick type C disease
Schultz, Mark L, Schache, Kylie J, Azaria, Ruth D, Kuiper, Esmée Q, Erwood, Steven, Ivakine, Evgueni A, Farhat, Nicole Y, Porter, Forbes D, Pathmasiri, Koralege C, Cologna, Stephanie M, Uhler, Michael D, Lieberman, Andrew P
Published in JCI insight (08.12.2022)
Published in JCI insight (08.12.2022)
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Journal Article
Clarifying lysosomal storage diseases
Schultz, Mark L, Tecedor, Luis, Chang, Michael, Davidson, Beverly L
Published in Trends in neurosciences (Regular ed.) (01.08.2011)
Published in Trends in neurosciences (Regular ed.) (01.08.2011)
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Journal Article
Enrichment of NPC1-deficient cells with the lipid LBPA stimulates autophagy, improves lysosomal function, and reduces cholesterol storage
Ilnytska, Olga, Lai, Kimberly, Gorshkov, Kirill, Schultz, Mark L., Tran, Bruce Nguyen, Jeziorek, Maciej, Kunkel, Thaddeus J., Azaria, Ruth D., McLoughlin, Hayley S., Waghalter, Miriam, Xu, Yang, Schlame, Michael, Altan-Bonnet, Nihal, Zheng, Wei, Lieberman, Andrew P., Dobrowolski, Radek, Storch, Judith
Published in The Journal of biological chemistry (01.07.2021)
Published in The Journal of biological chemistry (01.07.2021)
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Journal Article
Endogenous Protein–Protein Interaction Network of the NPC Cholesterol Transporter 1 in the Cerebral Cortex
Javanshad, Roshan, Nguyen, Thu T. A., Azaria, Ruth D., Li, Wenping, Edmison, Daisy, Gong, Liang-Wei, Gowrishankar, Swetha, Lieberman, Andrew P., Schultz, Mark L., Cologna, Stephanie M.
Published in Journal of proteome research (02.08.2024)
Published in Journal of proteome research (02.08.2024)
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Journal Article
Apolipoprotein-mimetic nanodiscs reduce lipid accumulation and improve liver function in acid sphingomyelinase deficiency
Halseth, Troy A., Correia, Adele B., Schultz, Mark L., Fawaz, Maria V., Kuiper, Esmée Q., Kumaran, Preethi, Dorsey, Kristen Hong, Schuchman, Edward H., Lieberman, Andrew P., Schwendeman, Anna
Published in Nanomedicine (01.09.2023)
Published in Nanomedicine (01.09.2023)
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Journal Article
LC3 Immunostaining in the Inferior Olivary Nuclei of Cats With Niemann-Pick Disease Type C1 Is Associated With Patterned Purkinje Cell Loss
Gurda, Brittney L, Bagel, Jessica H, Fisher, Samantha J, Schultz, Mark L, Lieberman, Andrew P, Hand, Peter, Vite, Charles H, Swain, Gary P
Published in Journal of neuropathology and experimental neurology (01.03.2018)
Published in Journal of neuropathology and experimental neurology (01.03.2018)
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Journal Article
Mutant induced neurons and humanized mice enable identification of Niemann-Pick C1 proteostatic therapies
Azaria, Ruth D., Correia, Adele B., Schache, Kylie J., Zapata, Manuela, Pathmasiri, Koralege C., Mohanty, Varshasnata, Nannapaneni, Dharma T., Ashfeld, Brandon L., Helquist, Paul, Wiest, Olaf, Ohgane, Kenji, Li, Qingqing, Fredenburg, Ross A., Blagg, Brian S.J., Cologna, Stephanie M., Schultz, Mark L., Lieberman, Andrew P.
Published in JCI insight (29.08.2024)
Published in JCI insight (29.08.2024)
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Journal Article