Loss of protein phosphatase 2A regulatory subunit PPP2R5A is associated with increased incidence of stress-induced proarrhythmia
Pluteanu, Florentina, Glaser, Dennis, Massing, Fabian, Schulte, Jan S, Kirchhefer, Uwe
Published in Frontiers in cardiovascular medicine (28.05.2024)
Published in Frontiers in cardiovascular medicine (28.05.2024)
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Atrial fibrillation and heart failure-associated remodeling of two-pore-domain potassium (K2P) channels in murine disease models: focus on TASK-1
Wiedmann, Felix, Schulte, Jan S., Gomes, Bruna, Zafeiriou, Maria-Patapia, Ratte, Antonius, Rathjens, Franziska, Fehrmann, Edda, Scholz, Beatrix, Voigt, Niels, Müller, Frank Ulrich, Thomas, Dierk, Katus, Hugo A., Schmidt, Constanze
Published in Basic research in cardiology (01.07.2018)
Published in Basic research in cardiology (01.07.2018)
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Induction of ICER is superseded by smICER, challenging the impact of ICER under chronic beta‐adrenergic stimulation
Seidl, Matthias D., Fels, Benedikt, Kranick, Daniel, Sternberg, Alexandra, Grimm, Kristina, Stümpel, Frank T., Pluteanu, Florentina, Schulte, Jan S., Heinick, Alexander, Kojima, Nobuhiko, Endo, Shogo, Huge, Andreas, Stoll, Monika, Müller, Frank U.
Published in The FASEB journal (01.08.2020)
Published in The FASEB journal (01.08.2020)
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Suppression of Early and Late Afterdepolarizations by Heterozygous Knockout of the Na+/Ca2+ Exchanger in a Murine Model
Bögeholz, Nils, Pauls, Paul, Bauer, B Klemens, Schulte, Jan S, Dechering, Dirk G, Frommeyer, Gerrit, Kirchhefer, Uwe, Goldhaber, Joshua I, Müller, Frank U, Eckardt, Lars, Pott, Christian
Published in Circulation. Arrhythmia and electrophysiology (01.10.2015)
Published in Circulation. Arrhythmia and electrophysiology (01.10.2015)
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Journal Article
Increased in vivo perpetuation of whole-heart ventricular arrhythmia in heterozygous Na+/Ca2+ exchanger knockout mice
Bögeholz, Nils, Knappe, Vincent, Pauls, Paul, Schulte, Jan S., Goldhaber, Joshua I., Müller, Frank U., Nickenig, Georg, Eckardt, Lars, Schrickel, Jan W., Beiert, Thomas
Published in International journal of cardiology. Heart & vasculature (01.02.2023)
Published in International journal of cardiology. Heart & vasculature (01.02.2023)
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Journal Article
Distinct Occurrence of Proarrhythmic Afterdepolarizations in Atrial Versus Ventricular Cardiomyocytes: Implications for Translational Research on Atrial Arrhythmia
Bögeholz, Nils, Pauls, Paul, Dechering, Dirk G, Frommeyer, Gerrit, Goldhaber, Joshua I, Pott, Christian, Eckardt, Lars, Müller, Frank U, Schulte, Jan S
Published in Frontiers in pharmacology (21.08.2018)
Published in Frontiers in pharmacology (21.08.2018)
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Journal Article
The Effects of SEA0400 on Ca2+ Transient Amplitude and Proarrhythmia Depend on the Na+/Ca2+ Exchanger Expression Level in Murine Models
Bögeholz, Nils, Schulte, Jan S., Kaese, Sven, Bauer, B. Klemens, Pauls, Paul, Dechering, Dirk G., Frommeyer, Gerrit, Goldhaber, Joshua I., Kirchhefer, Uwe, Eckardt, Lars, Pott, Christian, Müller, Frank U.
Published in Frontiers in pharmacology (21.09.2017)
Published in Frontiers in pharmacology (21.09.2017)
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Journal Article
First report on an inotropic peptide activating tetrodotoxin-sensitive, "neuronal" sodium currents in the heart
Kirchhof, Paulus, Tal, Tzachy, Fabritz, Larissa, Klimas, Jan, Nesher, Nir, Schulte, Jan S, Ehling, Petra, Kanyshkova, Tatayana, Budde, Thomas, Nikol, Sigrid, Fortmueller, Lisa, Stallmeyer, Birgit, Müller, Frank U, Schulze-Bahr, Eric, Schmitz, Wilhelm, Zlotkin, Eliahu, Kirchhefer, Uwe
Published in Circulation. Heart failure (01.01.2015)
Published in Circulation. Heart failure (01.01.2015)
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Journal Article
Impaired myocellular Ca2+ cycling in protein phosphatase PP2A-B56α KO mice is normalized by β-adrenergic stimulation
Glaser, Dennis, Heinick, Alexander, Herting, Julius R., Massing, Fabian, Müller, Frank U., Pauls, Paul, Rozhdestvensky, Timofey S., Schulte, Jan S., Seidl, Matthias D., Skryabin, Boris V., Stümpel, Frank, Kirchhefer, Uwe
Published in The Journal of biological chemistry (01.09.2022)
Published in The Journal of biological chemistry (01.09.2022)
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Journal Article
Stretch-activated two-pore-domain (K2P) potassium channels in the heart: Focus on atrial fibrillation and heart failure
Schmidt, Constanze, Wiedmann, Felix, Kallenberger, Stefan M., Ratte, Antonius, Schulte, Jan S., Scholz, Beatrix, Müller, Frank Ulrich, Voigt, Niels, Zafeiriou, Maria-Patapia, Ehrlich, Joachim R., Tochtermann, Ursula, Veres, Gábor, Ruhparwar, Arjang, Karck, Matthias, Katus, Hugo A., Thomas, Dierk
Published in Progress in biophysics and molecular biology (01.11.2017)
Published in Progress in biophysics and molecular biology (01.11.2017)
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Journal Article
Corrigendum to “Chronic β-adrenergic stimulation reverses depressed Ca handling in mice overexpressing inhibitor-2 of protein phosphatase 1” [J Mol Cell Cardiol 125 (2018) 195–204]
Kirchhefer, Uwe, Hammer, Elke, Heinick, Alexander, Herpertz, Thomas, Isensee, Gunnar, Müller, Frank U., Neumann, Joachim, Schulte, Jan S., Schulte, Kirsten, Seidl, Matthias D., Boknik, Peter
Published in Journal of molecular and cellular cardiology (01.06.2020)
Published in Journal of molecular and cellular cardiology (01.06.2020)
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Journal Article
Chronic β-adrenergic stimulation reverses depressed Ca handling in mice overexpressing inhibitor-2 of protein phosphatase 1
Kirchhefer, Uwe, Hammer, Elke, Heinick, Alexander, Herpertz, Thomas, Isensee, Gunnar, Müller, Frank U., Neumann, Joachim, Schulte, Kirsten, Seidl, Matthias D., Boknik, Peter, Schulte, Jan S.
Published in Journal of molecular and cellular cardiology (01.12.2018)
Published in Journal of molecular and cellular cardiology (01.12.2018)
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Journal Article
Cardiac Function Is Regulated by B56α-mediated Targeting of Protein Phosphatase 2A (PP2A) to Contractile Relevant Substrates
Kirchhefer, Uwe, Brekle, Christiane, Eskandar, John, Isensee, Gunnar, Kučerová, Dana, Müller, Frank U., Pinet, Florence, Schulte, Jan S., Seidl, Matthias D., Boknik, Peter
Published in The Journal of biological chemistry (05.12.2014)
Published in The Journal of biological chemistry (05.12.2014)
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Journal Article
Annexin A4 is a novel direct regulator of adenylyl cyclase type 5
Heinick, Alexander, Husser, Xenia, Himmler, Kirsten, Kirchhefer, Uwe, Nunes, Frank, Schulte, Jan S, Seidl, Matthias D, Rolfes, Christina, Dedman, John R, Kaetzel, Marcia A, Gerke, Volker, Schmitz, Wilhelm, Müller, Frank U
Published in The FASEB journal (01.09.2015)
Published in The FASEB journal (01.09.2015)
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Tropisetron suppresses collagen synthesis in skin fibroblasts via [alpha]7 nicotinic acetylcholine receptor and attenuates fibrosis in a scleroderma mouse model
Stegemann, Agatha, Sindrilaru, Anca, Eckes, Beate, del Rey, Adriana, Heinick, Alexander, Schulte, Jan S, Müller, Frank U, Grando, Sergei A, Fiebich, Bernd L, Scharffetter-Kochanek, Karin, Luger, Thomas A, Böhm, Markus
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.03.2013)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.03.2013)
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Journal Article
Overexpression of the Na + /Ca 2+ exchanger influences ouabain-mediated spontaneous Ca 2+ activity but not positive inotropy
Bögeholz, Nils, Pauls, Paul, Bauer, Bastian K, Schulte, Jan S, Frommeyer, Gerrit, Dechering, Dirk G, Boknik, Peter, Kirchhefer, Uwe, Müller, Frank U, Pott, Christian, Eckardt, Lars
Published in Fundamental & clinical pharmacology (01.02.2019)
Published in Fundamental & clinical pharmacology (01.02.2019)
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Journal Article
Overexpression of the Na+/Ca2+ exchanger influences ouabain‐mediated spontaneous Ca2+ activity but not positive inotropy
Bögeholz, Nils, Pauls, Paul, Bauer, Bastian K., Schulte, Jan S., Frommeyer, Gerrit, Dechering, Dirk G., Boknik, Peter, Kirchhefer, Uwe, Müller, Frank U., Pott, Christian, Eckardt, Lars
Published in Fundamental & clinical pharmacology (01.02.2019)
Published in Fundamental & clinical pharmacology (01.02.2019)
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Journal Article
Overexpression of cAMP-response element modulator causes abnormal growth and development of the atrial myocardium resulting in a substrate for sustained atrial fibrillation in mice
Kirchhof, Paulus, Marijon, Eloi, Fabritz, Larissa, Li, Na, Wang, Wei, Wang, Tiannan, Schulte, Kirsten, Hanstein, Juliane, Schulte, Jan S, Vogel, Mathis, Mougenot, Nathalie, Laakmann, Sandra, Fortmueller, Lisa, Eckstein, Jens, Verheule, Sander, Kaese, Sven, Staab, Ariane, Grote-Wessels, Stephanie, Schotten, Ulrich, Moubarak, Ghassan, Wehrens, Xander H.T, Schmitz, Wilhelm, Hatem, Stéphane, Müller, Frank Ulrich
Published in International journal of cardiology (20.06.2013)
Published in International journal of cardiology (20.06.2013)
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Journal Article
Proarrhythmia in a non-failing murine model of cardiac-specific Na+/Ca2+ exchanger overexpression: whole heart and cellular mechanisms
Pott, Christian, Muszynski, Adam, Ruhe, Matthias, Bögeholz, N., Schulte, Jan S., Milberg, Peter, Mönnig, Gerold, Fabritz, Larissa, Goldhaber, Joshua I., Breithardt, Günter, Schmitz, Wilhelm, Philipson, Kenneth D., Eckardt, Lars, Kirchhof, Paulus, Müller, Frank U.
Published in Basic research in cardiology (01.03.2012)
Published in Basic research in cardiology (01.03.2012)
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Journal Article
Corrigendum to “Overexpression of cAMP-response element modulator causes abnormal growth and development of the atrial myocardium resulting in a substrate for sustained atrial fibrillation in mice” Int J Cardiol 166 (2013), 366–74
Kirchhof, Paulus, Marijon, Eloi, Fabritz, Larissa, Li, Na, Wang, Wei, Wang, Tiannan, Schulte, Kirsten, Hanstein, Juliane, Schulte, Jan S, Vogel, Mathis, Mougenot, Nathalie, Laakmann, Sandra, Fortmueller, Lisa, Eckstein, Jens, Verheule, Sander, Kaese, Sven, Staab, Ariane, Grote-Wessels, Stephanie, Schotten, Ulrich, Moubarak, Ghassan, Wehrens, Xander H.T, Schmitz, Wilhelm, Hatem, Stéphane, Müller, Frank Ulrich
Published in International journal of cardiology (01.04.2014)
Published in International journal of cardiology (01.04.2014)
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