Dual Regioselective Targeting the Same Receptor in Nanoparticle-Mediated Combination Immuno/Chemotherapy for Enhanced Image-Guided Cancer Treatment
Shipunova, Victoria O, Komedchikova, Elena N, Kotelnikova, Polina A, Zelepukin, Ivan V, Schulga, Alexey A, Proshkina, Galina M, Shramova, Elena I, Kutscher, Hilliard L, Telegin, Georgij B, Kabashin, Andrei V, Prasad, Paras N, Deyev, Sergey M
Published in ACS nano (27.10.2020)
Published in ACS nano (27.10.2020)
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Journal Article
HER2-Specific Targeted Toxin DARPin-LoPE: Immunogenicity and Antitumor Effect on Intraperitoneal Ovarian Cancer Xenograft Model
Sokolova, Evgeniya A, Shilova, Olga N, Kiseleva, Daria V, Schulga, Alexey A, Balalaeva, Irina V, Deyev, Sergey M
Published in International journal of molecular sciences (15.05.2019)
Published in International journal of molecular sciences (15.05.2019)
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Journal Article
Radionuclide Molecular Imaging of EpCAM Expression in Triple-Negative Breast Cancer Using the Scaffold Protein DARPin Ec1
Vorobyeva, Anzhelika, Bezverkhniaia, Ekaterina, Konovalova, Elena, Schulga, Alexey, Garousi, Javad, Vorontsova, Olga, Abouzayed, Ayman, Orlova, Anna, Deyev, Sergey, Tolmachev, Vladimir
Published in Molecules (Basel, Switzerland) (14.10.2020)
Published in Molecules (Basel, Switzerland) (14.10.2020)
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Journal Article
Recombinant targeted toxin based on HER2-specific DARPin possesses a strong selective cytotoxic effect in vitro and a potent antitumor activity in vivo
Sokolova, Evgeniya, Proshkina, Galina, Kutova, Olga, Shilova, Olga, Ryabova, Anastasiya, Schulga, Alexey, Stremovskiy, Oleg, Zdobnova, Tatiana, Balalaeva, Irina, Deyev, Sergey
Published in Journal of controlled release (10.07.2016)
Published in Journal of controlled release (10.07.2016)
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Journal Article
UCNP-based Photoluminescent Nanomedicines for Targeted Imaging and Theranostics of Cancer
Guryev, Evgenii L, Smyshlyaeva, Anita S, Shilyagina, Natalia Y, Sokolova, Evgeniya A, Shanwar, Samah, Kostyuk, Alexey B, Lyubeshkin, Alexander V, Schulga, Alexey A, Konovalova, Elena V, Lin, Quan, Roy, Indrajit, Balalaeva, Irina V, Deyev, Sergey M, Zvyagin, Andrei V
Published in Molecules (Basel, Switzerland) (19.09.2020)
Published in Molecules (Basel, Switzerland) (19.09.2020)
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Journal Article
Self-assembling nanoparticles biofunctionalized with magnetite-binding protein for the targeted delivery to HER2/neu overexpressing cancer cells
Shipunova, Victoria O., Kotelnikova, Polina A., Aghayeva, Ulkar F., Stremovskiy, Oleg A., Novikov, Ilya A., Schulga, Alexey A., Nikitin, Maxim P., Deyev, Sergey M.
Published in Journal of magnetism and magnetic materials (01.01.2019)
Published in Journal of magnetism and magnetic materials (01.01.2019)
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Journal Article
On the prevention of kidney uptake of radiolabeled DARPins
Altai, Mohamed, Garousi, Javad, Rinne, Sara S., Schulga, Alexey, Deyev, Sergey, Vorobyeva, Anzhelika
Published in EJNMMI research (04.02.2020)
Published in EJNMMI research (04.02.2020)
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Journal Article
Preclinical Evaluation of HER2-Targeting DARPin G3: Impact of Albumin-Binding Domain (ABD) Fusion
Deyev, Sergey M, Oroujeni, Maryam, Garousi, Javad, Gräslund, Torbjörn, Li, Ruonan, Rosly, Alia Hani Binti, Orlova, Anna, Konovalova, Elena, Schulga, Alexey, Vorobyeva, Anzhelika, Tolmachev, Vladimir
Published in International journal of molecular sciences (01.04.2024)
Published in International journal of molecular sciences (01.04.2024)
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Journal Article
Feasibility of Co-Targeting HER3 and EpCAM Using Seribantumab and DARPin-Toxin Fusion in a Pancreatic Cancer Xenograft Model
Xu, Tianqi, Schulga, Alexey, Konovalova, Elena, Rinne, Sara S, Zhang, Hongchao, Vorontsova, Olga, Orlova, Anna, Deyev, Sergey M, Tolmachev, Vladimir, Vorobyeva, Anzhelika
Published in International journal of molecular sciences (02.02.2023)
Published in International journal of molecular sciences (02.02.2023)
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Journal Article
Direct Intra-Patient Comparison of Scaffold Protein-Based Tracers, [ 99m Tc]Tc-ADAPT6 and [ 99m Tc]Tc-(HE) 3 -G3, for Imaging of HER2-Positive Breast Cancer
Bragina, Olga, Chernov, Vladimir, Schulga, Alexey, Konovalova, Elena, Hober, Sophia, Deyev, Sergey, Sörensen, Jens, Tolmachev, Vladimir
Published in Cancers (11.06.2023)
Published in Cancers (11.06.2023)
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Journal Article
Comparative Preclinical Evaluation of Peptide-Based Chelators for the Labeling of DARPin G3 with 99mTc for Radionuclide Imaging of HER2 Expression in Cancer
Larkina, Mariia, Plotnikov, Evgenii, Bezverkhniaia, Ekaterina, Shabanova, Yulia, Tretyakova, Maria, Yuldasheva, Feruza, Zelchan, Roman, Schulga, Alexey, Konovalova, Elena, Vorobyeva, Anzhelika, Garousi, Javad, Gräslund, Torbjörn, Belousov, Mikhail, Tolmachev, Vladimir, Deyev, Sergey
Published in International journal of molecular sciences (03.11.2022)
Published in International journal of molecular sciences (03.11.2022)
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Journal Article
Feasibility of Imaging EpCAM Expression in Ovarian Cancer Using Radiolabeled DARPin Ec1
Vorobyeva, Anzhelika, Konovalova, Elena, Xu, Tianqi, Schulga, Alexey, Altai, Mohamed, Garousi, Javad, Rinne, Sara S, Orlova, Anna, Tolmachev, Vladimir, Deyev, Sergey
Published in International journal of molecular sciences (07.05.2020)
Published in International journal of molecular sciences (07.05.2020)
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Journal Article
Indirect Radioiodination of DARPin G3 Using N-succinimidyl- Para -Iodobenzoate Improves the Contrast of HER2 Molecular Imaging
Vorobyeva, Anzhelika, Schulga, Alexey, Rinne, Sara S, Günther, Tyran, Orlova, Anna, Deyev, Sergey, Tolmachev, Vladimir
Published in International journal of molecular sciences (21.06.2019)
Published in International journal of molecular sciences (21.06.2019)
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Journal Article
Direct In Vivo Comparison of 99mTc-Labeled Scaffold Proteins, DARPin G3 and ADAPT6, for Visualization of HER2 Expression and Monitoring of Early Response for Trastuzumab Therapy
Tolmachev, Vladimir, Bodenko, Vitalina, Oroujeni, Maryam, Deyev, Sergey, Konovalova, Elena, Schulga, Alexey, Lindbo, Sarah, Hober, Sophia, Bragina, Olga, Orlova, Anna, Vorobyeva, Anzhelika
Published in International journal of molecular sciences (02.12.2022)
Published in International journal of molecular sciences (02.12.2022)
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Journal Article
Spatial Structure and pH-dependent Conformational Diversity of Dimeric Transmembrane Domain of the Receptor Tyrosine Kinase EphA1
Bocharov, Eduard V., Mayzel, Maxim L., Volynsky, Pavel E., Goncharuk, Marina V., Ermolyuk, Yaroslav S., Schulga, Alexey A., Artemenko, Elena O., Efremov, Roman G., Arseniev, Alexander S.
Published in The Journal of biological chemistry (24.10.2008)
Published in The Journal of biological chemistry (24.10.2008)
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Journal Article
Phase I Clinical Evaluation of Designed Ankyrin Repeat Protein [99mTc]Tc(CO)3-(HE)3-Ec1 for Visualization of EpCAM-Expressing Lung Cancer
Zelchan, Roman, Chernov, Vladimir, Medvedeva, Anna, Rybina, Anastasia, Bragina, Olga, Mishina, Elizaveta, Larkina, Mariia, Varvashenya, Ruslan, Fominykh, Anastasia, Schulga, Alexey, Konovalova, Elena, Vorobyeva, Anzhelika, Orlova, Anna, Tashireva, Liubov, Deyev, Sergey M., Tolmachev, Vladimir
Published in Cancers (10.08.2024)
Published in Cancers (10.08.2024)
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Journal Article
Left-Handed Dimer of EphA2 Transmembrane Domain: Helix Packing Diversity among Receptor Tyrosine Kinases
Bocharov, Eduard V., Mayzel, Maxim L., Volynsky, Pavel E., Mineev, Konstantin S., Tkach, Elena N., Ermolyuk, Yaroslav S., Schulga, Alexey A., Efremov, Roman G., Arseniev, Alexander S.
Published in Biophysical journal (03.03.2010)
Published in Biophysical journal (03.03.2010)
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Journal Article
Targeted Delivery of HSP70 to Tumor Cells via Supramolecular Complex Based on HER2-Specific DARPin9_29 and the Barnase:Barstar Pair
Alekseeva, Ludmila G, Ovsyanikova, Olga V, Schulga, Alexey A, Grechikhina, Maria V, Shustova, Olga A, Kovalenko, Elena I, Svirshchevskaya, Elena V, Deyev, Sergey M, Sapozhnikov, Alexander M
Published in Cells (Basel, Switzerland) (01.02.2024)
Published in Cells (Basel, Switzerland) (01.02.2024)
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Journal Article
Influence of the Position and Composition of Radiometals and Radioiodine Labels on Imaging of Epcam Expression in Prostate Cancer Model Using the DARPin Ec1
Deyev, Sergey M., Xu, Tianqi, Liu, Yongsheng, Schulga, Alexey, Konovalova, Elena, Garousi, Javad, Rinne, Sara S., Larkina, Maria, Ding, Haozhong, Gräslund, Torbjörn, Orlova, Anna, Tolmachev, Vladimir, Vorobyeva, Anzhelika
Published in Cancers (17.07.2021)
Published in Cancers (17.07.2021)
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Journal Article
Unique Dimeric Structure of BNip3 Transmembrane Domain Suggests Membrane Permeabilization as a Cell Death Trigger
Bocharov, Eduard V., Pustovalova, Yulia E., Pavlov, Konstantin V., Volynsky, Pavel E., Goncharuk, Marina V., Ermolyuk, Yaroslav S., Karpunin, Dmitry V., Schulga, Alexey A., Kirpichnikov, Michail P., Efremov, Roman G., Maslennikov, Innokenty V., Arseniev, Alexander S.
Published in The Journal of biological chemistry (01.06.2007)
Published in The Journal of biological chemistry (01.06.2007)
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