Clinical Drug–Drug Interaction Potential of BFE1224, Prodrug of Antifungal Ravuconazole, Using Two Types of Cocktails in Healthy Subjects
Ishii, Yasuyuki, Ito, Yuko, Matsuki, Shunji, Sanpei, Kasumi, Ogawa, Osamu, Takeda, Kenji, Schuck, Edgar L., Uemura, Naoto
Published in Clinical and translational science (01.09.2018)
Published in Clinical and translational science (01.09.2018)
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Physiological, pharmacokinetic, and pharmacodynamic changes in space
Graebe, Annemarie, Schuck, Edgar L, Lensing, Petra, Putcha, Lakshmi, Derendorf, Hartmut
Published in Journal of clinical pharmacology (01.08.2004)
Published in Journal of clinical pharmacology (01.08.2004)
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Pharmacokinetic/ pharmacodynamic evaluation of anti-infective agents
Schuck, Edgar L, Derendorf, Hartmut
Published in Expert review of anti-infective therapy (01.06.2005)
Published in Expert review of anti-infective therapy (01.06.2005)
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Pharmacokinetic characterization of a natural product–inspired novel MEK1 inhibitor E6201 in preclinical species
Kumar, Vipul, Schuck, Edgar L., Pelletier, Robert D., Farah, Nadia, Condon, Krista B., Ye, Meng, Rowbottom, Christopher, King, Belinda M., Zhang, Zhi-Yi, Saxton, Philip L., Wong, Y. Nancy
Published in Cancer chemotherapy and pharmacology (2012)
Published in Cancer chemotherapy and pharmacology (2012)
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E2027, A NOVEL PHOSPHODIESTERASE-9 (PDE9) INHIBITOR IN DEVELOPMENT FOR TREATMENT OF DEMENTIA WITH LEWY BODIES (DLB), SHOWED NO CLINICALLY SIGNIFICANT DRUG INTERACTION WITH DILTIAZEM
Landry, Ishani, Lai, Robert YK, Boyd, Peter, Aluri, Jagadeesh, Chang, Min-Kun, Schuck, Edgar L., Luthman, Johan
Published in Alzheimer's & dementia (01.07.2018)
Published in Alzheimer's & dementia (01.07.2018)
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P1‐055: E2027, A NOVEL PHOSPHODIESTERASE‐9 (PDE9) INHIBITOR IN DEVELOPMENT FOR TREATMENT OF DEMENTIA WITH LEWY BODIES (DLB), SHOWED NO CLINICALLY SIGNIFICANT DRUG INTERACTION WITH DILTIAZEM
Landry, Ishani, Lai, Robert YK, Boyd, Peter, Aluri, Jagadeesh, Chang, Min-Kun, Schuck, Edgar L., Luthman, Johan
Published in Alzheimer's & dementia (01.07.2018)
Published in Alzheimer's & dementia (01.07.2018)
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P4‐657: POPULATION PHARMACOKINETIC/PHARMACODYNAMIC ANALYSES OF BAN2401 IN PATIENTS WITH EARLY ALZHEIMER'S DISEASE: CORRELATION OF BAN2401 EXPOSURE, PET STANDARD UPTAKE VALUE RATIO, AND COGNITIVE OUTCOMES
Schuck, Edgar L., Reyderman, Larisa, Hayato, Seiichi, Takenaka, Osamu, Swanson, Chad J., Lai, Robert YK, Hussein, Ziad, Ferry, Jim
Published in Alzheimer's & dementia (01.07.2019)
Published in Alzheimer's & dementia (01.07.2019)
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Journal Article
O1‐12‐06: PHASE 1 MULTIPLE ASCENDING DOSE (MAD) STUDY OF PHOSPHODIESTERASE‐9 INHIBITOR E2027: CONFIRMATION OF TARGET ENGAGEMENT AND SELECTION OF PHASE 2 DOSE IN DEMENTIA WITH LEWY BODIES
Landry, Ishani, Lai, Robert YK, Boyd, Peter, Aluri, Jagadeesh, Chang, Min-Kun, Ino, Mitsuhiro, Horie, Kanta, Schuck, Edgar L., Luthman, Johan
Published in Alzheimer's & dementia (01.07.2018)
Published in Alzheimer's & dementia (01.07.2018)
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[P1–056]: POPULATION PHARMACOKINETIC‐PHARMACODYNAMIC (PK/PD) MODELING OF E2027, A SELECTIVE PHOSPHODIESTERASE‐9 (PDE9) INHIBITOR, FOLLOWING SINGLE ASCENDING ORAL DOSES IN HEALTHY VOLUNTEERS
Schuck, Edgar L., Lai, Robert Y.K., Aluri, Jagadeesh, Hussein, Ziad, Ino, Mitsuhiro, Kotani, Sadaharu, Chang, Min‐Kun, Savant‐Landry, Ishani, Luthman, Johan
Published in Alzheimer's & dementia (01.07.2017)
Published in Alzheimer's & dementia (01.07.2017)
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Journal Article
PHASE 1 INVESTIGATION INTO THE SAFETY, TOLERABILITY, PHARMACOKINETICS (PK) AND PHARMACODYNAMICS (PD) OF E2027, A SELECTIVE PHOSPHODIESTERASE-9 (PDE9) INHIBITOR
Lai, Robert Y.K., Gordon, Robert, Chang, Min-Kun, Boyd, Peter, Savant-Landry, Ishani, Aluri, Jagadeesh, Ino, Mitsuhiro, Horie, Kanta, Kotani, Sadaharu, Schuck, Edgar L., Luthman, Johan
Published in Alzheimer's & dementia (01.07.2017)
Published in Alzheimer's & dementia (01.07.2017)
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Journal Article
POPULATION PHARMACOKINETIC/PHARMACODYNAMIC ANALYSES OF BAN2401 IN PATIENTS WITH EARLY ALZHEIMER’S DISEASE: CORRELATION OF BAN2401 EXPOSURE, PET STANDARD UPTAKE VALUE RATIO, AND COGNITIVE OUTCOMES
Schuck, Edgar L., Reyderman, Larisa, Hayato, Seiichi, Takenaka, Osamu, Swanson, Chad J., Lai, Robert YK, Hussein, Ziad, Ferry, Jim
Published in Alzheimer's & dementia (01.07.2019)
Published in Alzheimer's & dementia (01.07.2019)
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Journal Article
P4‐657: POPULATION PHARMACOKINETIC/PHARMACODYNAMIC ANALYSES OF BAN2401 IN PATIENTS WITH EARLY ALZHEIMER'S DISEASE: CORRELATION OF BAN2401 EXPOSURE, PET STANDARD UPTAKE VALUE RATIO, AND COGNITIVE OUTCOMES
Schuck, Edgar L., Reyderman, Larisa, Hayato, Seiichi, Takenaka, Osamu, Swanson, Chad J., Lai, Robert YK, Hussein, Ziad, Ferry, Jim
Published in Alzheimer's & dementia (01.07.2019)
Published in Alzheimer's & dementia (01.07.2019)
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Journal Article
POPULATION PHARMACOKINETIC-PHARMACODYNAMIC (PK/PD) MODELING OF E2027, A SELECTIVE PHOSPHODIESTERASE-9 (PDE9) INHIBITOR, FOLLOWING SINGLE ASCENDING ORAL DOSES IN HEALTHY VOLUNTEERS
Schuck, Edgar L., Lai, Robert Y.K., Aluri, Jagadeesh, Hussein, Ziad, Ino, Mitsuhiro, Kotani, Sadaharu, Chang, Min-Kun, Savant-Landry, Ishani, Luthman, Johan
Published in Alzheimer's & dementia (01.07.2017)
Published in Alzheimer's & dementia (01.07.2017)
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Journal Article