The N-terminus of the Aspergillus fumigatus group III hybrid histidine kinase TcsC is essential for its physiological activity and targets the protein to the nucleus
Vincek, Anna, Wolf, Anja, Thomas, Astrid, Ebel, Frank, Schruefer, Sebastian
Published in mBio (17.07.2024)
Published in mBio (17.07.2024)
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Journal Article
Distinct transcriptional responses to fludioxonil in Aspergillus fumigatus and its ΔtcsC and Δskn7 mutants reveal a crucial role for Skn7 in the cell wall reorganizations triggered by this antifungal
Schruefer, Sebastian, Pschibul, Annica, Wong, Sarah Sze Wah, Sae-Ong, Tongta, Wolf, Thomas, Schäuble, Sascha, Panagiotou, Gianni, Brakhage, Axel A, Aimanianda, Vishukumar, Kniemeyer, Olaf, Ebel, Frank
Published in BMC genomics (14.11.2023)
Published in BMC genomics (14.11.2023)
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Phosphatidylinositol 3-Kinase (PI3K) Orchestrates Aspergillus fumigatus-Induced Eosinophil Activation Independently of Canonical Toll-Like Receptor (TLR)/C-Type-Lectin Receptor (CLR) Signaling
Dietschmann, Axel, Schruefer, Sebastian, Westermann, Stefanie, Henkel, Fiona, Castiglione, Kirstin, Willebrand, Ralf, Adam, Jasmin, Ruland, Jürgen, Lang, Roland, Sheppard, Donald C, Esser-von-Bieren, Julia, Radtke, Daniel, Krappmann, Sven, Voehringer, David
Published in mBio (30.08.2022)
Published in mBio (30.08.2022)
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Ypd1 Is an Essential Protein of the Major Fungal Pathogen Aspergillus fumigatus and a Key Element in the Phosphorelay That Is Targeted by the Antifungal Drug Fludioxonil
Schruefer, Sebastian, Spadinger, Anja, Kleinemeier, Christoph, Schmid, Laura, Ebel, Frank
Published in Frontiers in fungal biology (18.10.2021)
Published in Frontiers in fungal biology (18.10.2021)
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Combretastatin A-4 derived 5-(1-methyl-4-phenyl-imidazol-5-yl)indoles with superior cytotoxic and anti-vascular effects on chemoresistant cancer cells and tumors
Mahal, Katharina, Biersack, Bernhard, Schruefer, Sebastian, Resch, Marcus, Ficner, Ralf, Schobert, Rainer, Mueller, Thomas
Published in European journal of medicinal chemistry (08.08.2016)
Published in European journal of medicinal chemistry (08.08.2016)
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Journal Article
Distinct transcriptional responses to fludioxonil in Aspergillus fumigatus and its [DELA]tcsC and [DELA]skn7 mutants reveal a crucial role for Skn7 in the cell wall reorganizations triggered by this antifungal
Schruefer, Sebastian, Pschibul, Annica, Wong, Sarah Sze Wah, Sae-Ong, Tongta, Wolf, Thomas, Schäuble, Sascha, Panagiotou, Gianni, Brakhage, Axel A, Aimanianda, Vishukumar, Kniemeyer, Olaf, Ebel, Frank
Published in BMC genomics (14.11.2023)
Published in BMC genomics (14.11.2023)
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Journal Article
Pentafluorophenyl Substitution of Natural Di(indol‐3‐yl)methane Strongly Enhances Growth Inhibition and Apoptosis Induction in Various Cancer Cell Lines
Ahmad, Aamir, Dandawate, Prasad, Schruefer, Sebastian, Padhye, Subhash, Sarkar, Fazlul H., Schobert, Rainer, Biersack, Bernhard
Published in Chemistry & biodiversity (01.04.2019)
Published in Chemistry & biodiversity (01.04.2019)
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Journal Article
Biological evaluation of 4,5-diarylimidazoles with hydroxamic acid appendages as novel dual mode anticancer agents
Mahal, Katharina, Schruefer, Sebastian, Steinemann, Gustav, Rausch, Franziska, Schobert, Rainer, Biersack, Bernhard, Höpfner, Michael
Published in Cancer chemotherapy and pharmacology (01.04.2015)
Published in Cancer chemotherapy and pharmacology (01.04.2015)
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Ferrocene-substituted 3,3′-diindolylmethanes with improved anticancer activity
Muenzner, Julienne K., Ahmad, Aamir, Rothemund, Matthias, Schrüfer, Sebastian, Padhye, Subhash, Sarkar, Fazlul H., Schobert, Rainer, Biersack, Bernhard
Published in Applied organometallic chemistry (01.06.2016)
Published in Applied organometallic chemistry (01.06.2016)
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