Identification of the first small-molecule ligand of the neuronal receptor sortilin and structure determination of the receptor-ligand complex
Andersen, Jacob Lauwring, Schrøder, Tenna Juul, Christensen, Søren, Strandbygård, Dorthe, Pallesen, Lone Tjener, García-Alai, Maria Marta, Lindberg, Samsa, Langgård, Morten, Eskildsen, Jørgen Calí, David, Laurent, Tagmose, Lena, Simonsen, Klaus Baek, Maltas, Philip James, Rønn, Lars Christian Biilmann, de Jong, Inge E. M., Malik, Ibrahim John, Egebjerg, Jan, Karlsson, Jens-Jacob, Uppalanchi, Srinivas, Sakumudi, Durga Rao, Eradi, Pradheep, Watson, Steven P., Thirup, Søren
Published in Acta crystallographica. Section D, Biological crystallography. (01.02.2014)
Published in Acta crystallographica. Section D, Biological crystallography. (01.02.2014)
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The identification of AF38469: An orally bioavailable inhibitor of the VPS10P family sorting receptor Sortilin
Schroder, Tenna Juul, Christensen, Soren, Lindberg, Samsa, Langgard, Morten, David, Laurent, Maltas, Philip J., Eskildsen, Jorgen, Jacobsen, Jan, Tagmose, Lena, Simonsen, Klaus Baek, Ronn, Lars Christian Biilmann, de Jong, Inge E. M., Malik, Ibrahim J., Karlsson, Jens-Jakob, Bundgaard, Christoffer, Egebjerg, Jan, Stavenhagen, Jeffrey B., Strandbygard, Dorthe, Thirup, Soren, Andersen, Jacob Lauwring, Uppalanchi, Srinivas, Pervaram, Sridhar, Kasturi, Shiva Prasad, Eradi, Pradheep, Sakumudi, Durga Rao, Watson, Stephen P.
Published in Bioorganic & medicinal chemistry letters (01.01.2014)
Published in Bioorganic & medicinal chemistry letters (01.01.2014)
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Synthesis and SAR studies of analogues of 4-(3,3-dimethylbutyrylamino)-3,5-difluoro-N-thiazol-2-yl-benzamide (Lu AA41063) as adenosine A(2A) receptor ligands with improved aqueous solubility
Mikkelsen, Gitte Kobberoe, Langgard, Morten, Schroder, Tenna Juul, Kreilgaard, Mads, Jorgensen, Erling B., Brandt, Guillaume, Griffon, Yann, Boffey, Ray, Bang-Andersen, Benny
Published in Bioorganic & medicinal chemistry letters (15.03.2015)
Published in Bioorganic & medicinal chemistry letters (15.03.2015)
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Synthesis and SAR studies of analogues of 4-(3,3-dimethyl-butyrylamino)-3,5-difluoro-N-thiazol-2-yl-benzamide (Lu AA41063) as adenosine A2A receptor ligands with improved aqueous solubility
Mikkelsen, Gitte Kobberøe, Langgård, Morten, Schrøder, Tenna Juul, Kreilgaard, Mads, Jørgensen, Erling B., Brandt, Guillaume, Griffon, Yann, Boffey, Ray, Bang-Andersen, Benny
Published in Bioorganic & medicinal chemistry letters (15.03.2015)
Published in Bioorganic & medicinal chemistry letters (15.03.2015)
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Hit-to-lead optimization of a series of carboxamides of ethyl 2-amino-4-phenylthiazole-5-carboxylates as novel adenosine A2A receptor antagonists
GRAVEN SAMS, Anette, MIKKELSEN, Gitte Kobberøe, LARSEN, Mogens, TORUP, Lars, BRENNUM, Lise Tottrup, SCHRØDER, Tenna Juul, BANG-ANDERSEN, Benny
Published in Bioorganic & medicinal chemistry letters (01.09.2010)
Published in Bioorganic & medicinal chemistry letters (01.09.2010)
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Hit-to-lead optimization of a series of carboxamides of ethyl 2-amino-4-phenylthiazole-5-carboxylates as novel adenosine A 2A receptor antagonists
Sams, Anette Graven, Mikkelsen, Gitte Kobberøe, Larsen, Mogens, Torup, Lars, Brennum, Lise Tøttrup, Schrøder, Tenna Juul, Bang-Andersen, Benny
Published in Bioorganic & medicinal chemistry letters (2010)
Published in Bioorganic & medicinal chemistry letters (2010)
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