Practical implementation of DNA methylation and copy-number-based CNS tumor diagnostics: the Heidelberg experience
Capper, David, Stichel, Damian, Sahm, Felix, Jones, David T. W., Schrimpf, Daniel, Sill, Martin, Schmid, Simone, Hovestadt, Volker, Reuss, David E., Koelsche, Christian, Reinhardt, Annekathrin, Wefers, Annika K., Huang, Kristin, Sievers, Philipp, Ebrahimi, Azadeh, Schöler, Anne, Teichmann, Daniel, Koch, Arend, Hänggi, Daniel, Unterberg, Andreas, Platten, Michael, Wick, Wolfgang, Witt, Olaf, Milde, Till, Korshunov, Andrey, Pfister, Stefan M., von Deimling, Andreas
Published in Acta neuropathologica (01.08.2018)
Published in Acta neuropathologica (01.08.2018)
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Journal Article
IDH mutant diffuse and anaplastic astrocytomas have similar age at presentation and little difference in survival: a grading problem for WHO
Reuss, David E., Mamatjan, Yasin, Schrimpf, Daniel, Capper, David, Hovestadt, Volker, Kratz, Annekathrin, Sahm, Felix, Koelsche, Christian, Korshunov, Andrey, Olar, Adriana, Hartmann, Christian, Reijneveld, Jaap C., Wesseling, Pieter, Unterberg, Andreas, Platten, Michael, Wick, Wolfgang, Herold-Mende, Christel, Aldape, Kenneth, von Deimling, Andreas
Published in Acta neuropathologica (01.06.2015)
Published in Acta neuropathologica (01.06.2015)
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Journal Article
Prognostic impact of genetic alterations and methylation classes in meningioma
Berghoff, Anna S., Hielscher, Thomas, Ricken, Gerda, Furtner, Julia, Schrimpf, Daniel, Widhalm, Georg, Rajky, Ursula, Marosi, Christine, Hainfellner, Johannes A., Deimling, Andreas, Sahm, Felix, Preusser, Matthias
Published in Brain pathology (Zurich, Switzerland) (01.03.2022)
Published in Brain pathology (Zurich, Switzerland) (01.03.2022)
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Journal Article
Next-generation sequencing in routine brain tumor diagnostics enables an integrated diagnosis and identifies actionable targets
Sahm, Felix, Schrimpf, Daniel, Jones, David T. W., Meyer, Jochen, Kratz, Annekathrin, Reuss, David, Capper, David, Koelsche, Christian, Korshunov, Andrey, Wiestler, Benedikt, Buchhalter, Ivo, Milde, Till, Selt, Florian, Sturm, Dominik, Kool, Marcel, Hummel, Manuela, Bewerunge-Hudler, Melanie, Mawrin, Christian, Schüller, Ulrich, Jungk, Christine, Wick, Antje, Witt, Olaf, Platten, Michael, Herold-Mende, Christel, Unterberg, Andreas, Pfister, Stefan M., Wick, Wolfgang, von Deimling, Andreas
Published in Acta neuropathologica (01.06.2016)
Published in Acta neuropathologica (01.06.2016)
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Journal Article
Pan-mutant IDH1 inhibitor BAY 1436032 for effective treatment of IDH1 mutant astrocytoma in vivo
Pusch, Stefan, Krausert, Sonja, Fischer, Viktoria, Balss, Jörg, Ott, Martina, Schrimpf, Daniel, Capper, David, Sahm, Felix, Eisel, Jessica, Beck, Ann-Christin, Jugold, Manfred, Eichwald, Viktoria, Kaulfuss, Stefan, Panknin, Olaf, Rehwinkel, Hartmut, Zimmermann, Katja, Hillig, Roman C., Guenther, Judith, Toschi, Luisella, Neuhaus, Roland, Haegebart, Andrea, Hess-Stumpp, Holger, Bauser, Markus, Wick, Wolfgang, Unterberg, Andreas, Herold-Mende, Christel, Platten, Michael, von Deimling, Andreas
Published in Acta neuropathologica (01.04.2017)
Published in Acta neuropathologica (01.04.2017)
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Journal Article
Methylation array profiling of adult brain tumours: diagnostic outcomes in a large, single centre
Jaunmuktane, Zane, Capper, David, Jones, David T W, Schrimpf, Daniel, Sill, Martin, Dutt, Monika, Suraweera, Nirosha, Pfister, Stefan M, von Deimling, Andreas, Brandner, Sebastian
Published in Acta neuropathologica communications (20.02.2019)
Published in Acta neuropathologica communications (20.02.2019)
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Journal Article
Methylation-based classification of benign and malignant peripheral nerve sheath tumors
Röhrich, Manuel, Koelsche, Christian, Schrimpf, Daniel, Capper, David, Sahm, Felix, Kratz, Annekathrin, Reuss, Jana, Hovestadt, Volker, Jones, David T. W., Bewerunge-Hudler, Melanie, Becker, Albert, Weis, Joachim, Mawrin, Christian, Mittelbronn, Michel, Perry, Arie, Mautner, Victor-Felix, Mechtersheimer, Gunhild, Hartmann, Christian, Okuducu, Ali Fuat, Arp, Mirko, Seiz-Rosenhagen, Marcel, Hänggi, Daniel, Heim, Stefanie, Paulus, Werner, Schittenhelm, Jens, Ahmadi, Rezvan, Herold-Mende, Christel, Unterberg, Andreas, Pfister, Stefan M., von Deimling, Andreas, Reuss, David E.
Published in Acta neuropathologica (01.06.2016)
Published in Acta neuropathologica (01.06.2016)
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Journal Article
Infratentorial IDH-mutant astrocytoma is a distinct subtype
Banan, Rouzbeh, Stichel, Damian, Bleck, Anja, Hong, Bujung, Lehmann, Ulrich, Suwala, Abigail, Reinhardt, Annekathrin, Schrimpf, Daniel, Buslei, Rolf, Stadelmann, Christine, Ehlert, Karoline, Prinz, Marco, Acker, Till, Schittenhelm, Jens, Kaul, David, Schweizer, Leonille, Capper, David, Harter, Patrick N., Etminan, Nima, Jones, David T. W., Pfister, Stefan M., Herold-Mende, Christel, Wick, Wolfgang, Sahm, Felix, von Deimling, Andreas, Hartmann, Christian, Reuss, David E.
Published in Acta neuropathologica (01.10.2020)
Published in Acta neuropathologica (01.10.2020)
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Journal Article
Routine RNA sequencing of formalin-fixed paraffin-embedded specimens in neuropathology diagnostics identifies diagnostically and therapeutically relevant gene fusions
Stichel, Damian, Schrimpf, Daniel, Casalini, Belén, Meyer, Jochen, Wefers, Annika K., Sievers, Philipp, Korshunov, Andrey, Koelsche, Christian, Reuss, David E., Reinhardt, Annekathrin, Ebrahimi, Azadeh, Fernández-Klett, Francisco, Kessler, Tobias, Sturm, Dominik, Ecker, Jonas, Milde, Till, Herold-Mende, Christel, Witt, Olaf, Pfister, Stefan M., Wick, Wolfgang, Jones, David T. W., von Deimling, Andreas, Sahm, Felix
Published in Acta neuropathologica (01.11.2019)
Published in Acta neuropathologica (01.11.2019)
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Journal Article
Genomic characterization of DICER1-associated neoplasms uncovers molecular classes
Kommoss, Felix K F, Chong, Anne-Sophie, Chong, Anne-Laure, Pfaff, Elke, Jones, David T W, Hiemcke-Jiwa, Laura S, Kester, Lennart A, Flucke, Uta, Gessler, Manfred, Schrimpf, Daniel, Sahm, Felix, Clarke, Blaise A, Stewart, Colin J R, Wang, Yemin, Gilks, C Blake, Kommoss, Friedrich, Huntsman, David G, Schüller, Ulrich, Koelsche, Christian, McCluggage, W Glenn, von Deimling, Andreas, Foulkes, William D
Published in Nature communications (25.03.2023)
Published in Nature communications (25.03.2023)
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Journal Article
Integrated Genomic Classification of Melanocytic Tumors of the Central Nervous System Using Mutation Analysis, Copy Number Alterations, and DNA Methylation Profiling
Griewank, Klaus G, Koelsche, Christian, van de Nes, Johannes A P, Schrimpf, Daniel, Gessi, Marco, Möller, Inga, Sucker, Antje, Scolyer, Richard A, Buckland, Michael E, Murali, Rajmohan, Pietsch, Torsten, von Deimling, Andreas, Schadendorf, Dirk
Published in Clinical cancer research (15.09.2018)
Published in Clinical cancer research (15.09.2018)
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Journal Article
Comparison of transcriptome profiles between medulloblastoma primary and recurrent tumors uncovers novel variance effects in relapses
Okonechnikov, Konstantin, Federico, Aniello, Schrimpf, Daniel, Sievers, Philipp, Sahm, Felix, Koster, Jan, Jones, David T W, von Deimling, Andreas, Pfister, Stefan M, Kool, Marcel, Korshunov, Andrey
Published in Acta neuropathologica communications (12.01.2023)
Published in Acta neuropathologica communications (12.01.2023)
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Journal Article
DNA methylation‐based profiling of bone and soft tissue tumours: a validation study of the ‘DKFZ Sarcoma Classifier’
Lyskjær, Iben, De Noon, Solange, Tirabosco, Roberto, Rocha, Ana Maia, Lindsay, Daniel, Amary, Fernanda, Ye, Hongtao, Schrimpf, Daniel, Stichel, Damian, Sill, Martin, Koelsche, Christian, Pillay, Nischalan, Von Deimling, Andreas, Beck, Stephan, Flanagan, Adrienne M
Published in The journal of pathology. Clinical research (01.07.2021)
Published in The journal of pathology. Clinical research (01.07.2021)
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Journal Article
Molecular Transition of an Adult Low-Grade Brain Tumor to an Atypical Teratoid/Rhabdoid Tumor Over a Time-Course of 14 Years
Schweizer, Yvonne, Meszaros, Zsolt, Jones, David T.W, Koelsche, Christian, Boudalil, Miream, Fiesel, Petra, Schrimpf, Daniel, Piro, Rosario M, Brehmer, Stefanie, von Deimling, Andreas, Kerl, Ulrich, Seiz-Rosenhagen, Marcel, Capper, David
Published in Journal of neuropathology and experimental neurology (01.08.2017)
Published in Journal of neuropathology and experimental neurology (01.08.2017)
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Journal Article
Malignant Transformation of a Dysembryoplastic Neuroepithelial Tumor (DNET) Characterized by Genome-Wide Methylation Analysis
Heiland, Dieter Henrik, Staszewski, Ori, Hirsch, Martin, Masalha, Waseem, Franco, Pamela, Grauvogel, Jürgen, Capper, David, Schrimpf, Daniel, Urbach, Horst, Weyerbrock, Astrid
Published in Journal of neuropathology and experimental neurology (01.04.2016)
Published in Journal of neuropathology and experimental neurology (01.04.2016)
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Journal Article
Molecular analysis of pediatric CNS-PNET revealed nosologic heterogeneity and potent diagnostic markers for CNS neuroblastoma with FOXR2-activation
Korshunov, Andrey, Okonechnikov, Konstantin, Schmitt-Hoffner, Felix, Ryzhova, Marina, Sahm, Felix, Stichel, Damian, Schrimpf, Daniel, Reuss, David E, Sievers, Philipp, Suwala, Abigail Kora, Kumirova, Ella, Zheludkova, Olga, Golanov, Andrey, Jones, David T W, Pfister, Stefan M, Kool, Marcel, von Deimling, Andreas
Published in Acta neuropathologica communications (03.02.2021)
Published in Acta neuropathologica communications (03.02.2021)
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Journal Article
EpiDiP/NanoDiP: a versatile unsupervised machine learning edge computing platform for epigenomic tumour diagnostics
Hench, Jürgen, Hultschig, Claus, Brugger, Jon, Mariani, Luigi, Guzman, Raphael, Soleman, Jehuda, Leu, Severina, Benton, Miles, Stec, Irenäus Maria, Hench, Ivana Bratic, Hoffmann, Per, Harter, Patrick, Weber, Katharina J, Albers, Anne, Thomas, Christian, Hasselblatt, Martin, Schüller, Ulrich, Restelli, Lisa, Capper, David, Hewer, Ekkehard, Diebold, Joachim, Kolenc, Danijela, Schneider, Ulf C, Rushing, Elisabeth, Della Monica, Rosa, Chiariotti, Lorenzo, Sill, Martin, Schrimpf, Daniel, von Deimling, Andreas, Sahm, Felix, Kölsche, Christian, Tolnay, Markus, Frank, Stephan
Published in Acta neuropathologica communications (04.04.2024)
Published in Acta neuropathologica communications (04.04.2024)
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Journal Article
Reference on copy number variations in pleomorphic xanthoastrocytoma: Implications for diagnostic approach
Reuss, David E, Schrimpf, Daniel, Stichel, Damian, Ebrahimi, Azadeh, Dampier, Chris, Aldape, Kenneth, Snuderl, Matija, Capper, David, Sill, Martin, Jones, David T W, Pfister, Stefan M, Sahm, Felix, von Deimling, Andreas
Published in Free Neuropathology (01.11.2023)
Published in Free Neuropathology (01.11.2023)
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Journal Article
Genome-wide methylation profiling and copy number analysis in atypical fibroxanthomas and pleomorphic dermal sarcomas indicate a similar molecular phenotype
Koelsche, Christian, Stichel, Damian, Griewank, Klaus G, Schrimpf, Daniel, Reuss, David E, Bewerunge-Hudler, Melanie, Vokuhl, Christian, Dinjens, Winand N M, Petersen, Iver, Mittelbronn, Michel, Cuevas-Bourdier, Adrian, Buslei, Rolf, Pfister, Stefan M, Flucke, Uta, Mechtersheimer, Gunhild, Mentzel, Thomas, von Deimling, Andreas
Published in Clinical sarcoma research (14.02.2019)
Published in Clinical sarcoma research (14.02.2019)
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Journal Article
Heterogeneity of DNA methylation profiles and copy number alterations in 10782 adult-type glioblastomas, IDH-wildtype
Reuss, David E, Schrimpf, Daniel, Cherkezov, Asan, Suwala, Abigail K, Lausová, Tereza, Snuderl, Matija, Capper, David, Sill, Martin, Jones, David T W, Pfister, Stefan M, Sahm, Felix, von Deimling, Andreas
Published in Free Neuropathology (2024)
Published in Free Neuropathology (2024)
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Journal Article