Weight bearing as a measure of disease progression and efficacy of anti-inflammatory compounds in a model of monosodium iodoacetate-induced osteoarthritis
Bove, S.E, Calcaterra, S.L, Brooker, R.M, Huber, C.M, Guzman, R.E, Juneau, P.L, Schrier, D.J, Kilgore, K.S
Published in Osteoarthritis and cartilage (01.11.2003)
Published in Osteoarthritis and cartilage (01.11.2003)
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Synthesis, Structure−Activity Relationships, and in Vivo Evaluations of Substituted Di-tert-butylphenols as a Novel Class of Potent, Selective, and Orally Active Cyclooxygenase-2 Inhibitors. 2. 1,3,4- and 1,2,4-Thiadiazole Series
Song, Yuntao, Connor, David T, Sercel, Anthony D, Sorenson, Roderick J, Doubleday, Robert, Unangst, Paul C, Roth, Bruce D, Beylin, Vlad G, Gilbertsen, Richard B, Chan, Kam, Schrier, Denis J, Guglietta, Antonio, Bornemeier, Dirk A, Dyer, Richard D
Published in Journal of medicinal chemistry (08.04.1999)
Published in Journal of medicinal chemistry (08.04.1999)
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1,3,4-Oxadiazole, 1,3,4-thiadiazole, and 1,2,4-triazole analogs of the fenamates: in vitro inhibition of cyclooxygenase and 5-lipoxygenase activities
Boschelli, Diane H, Connor, David T, Bornemeier, Dirk A, Dyer, Richard D, Kennedy, John A, Kuipers, Paul J, Okonkwo, Godwin C, Schrier, Denis J, Wright, Clifford D
Published in Journal of medicinal chemistry (01.06.1993)
Published in Journal of medicinal chemistry (01.06.1993)
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Synthesis and biological evaluation of 5-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]oxazoles, -thiazoles, and -imidazoles: novel dual 5-lipoxygenase and cyclooxygenase inhibitors with antiinflammatory activity
Unangst, Paul C, Connor, David T, Cetenko, Wiaczeslaw A, Sorenson, Roderick J, Kostlan, Catherine R, Sircar, Jagadish C, Wright, Clifford D, Schrier, Denis J, Dyer, Richard D
Published in Journal of medicinal chemistry (01.01.1994)
Published in Journal of medicinal chemistry (01.01.1994)
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Nuclease-Resistant Ribozymes Decrease Stromelysin mRNA Levels in Rabbit Synovium Following Exogenous Delivery to the Knee Joint
Flory, Craig M., Pavco, Pamela A., Jarvis, Thale C., Lesch, Mark E., Wincott, Francine E., Beigelman, Leonid, Hunt, Stephen W., Schrier, Denis J.
Published in Proceedings of the National Academy of Sciences - PNAS (23.01.1996)
Published in Proceedings of the National Academy of Sciences - PNAS (23.01.1996)
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Styrylpyrazoles, styrylisoxazoles, and styrylisothiazoles. Novel 5-lipoxygenase and cyclooxygenase inhibitors
Flynn, Daniel L, Belliotti, Thomas R, Boctor, Amal M, Connor, David T, Kostlan, Catherine R, Nies, Donald E, Ortwine, Daniel F, Schrier, Denis J, Sircar, Jagadish C
Published in Journal of medicinal chemistry (01.02.1991)
Published in Journal of medicinal chemistry (01.02.1991)
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The biochemistry and pharmacology of PD 116124 (8-amino-2'-nordeoxyguanosine), an inhibitor of purine nucleoside phosphorylase (PNP)
Dong, M K, Scott, M E, Schrier, D J, Suto, M J, Sircar, J C, Black, A, Chang, T, Gilbertsen, R B
Published in The Journal of pharmacology and experimental therapeutics (01.01.1992)
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Published in The Journal of pharmacology and experimental therapeutics (01.01.1992)
Journal Article
3-Alkoxybenzo[b]thiophene-2-carboxamides as Inhibitors of Neutrophil-Endothelial Cell Adhesion
Boschelli, Diane H, Kramer, James B, Connor, David T, Lesch, Mark E, Schrier, Denis J, Ferin, Mark A, Wright, Clifford D
Published in Journal of medicinal chemistry (01.03.1994)
Published in Journal of medicinal chemistry (01.03.1994)
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Journal Article
Synthesis, Structure−Activity Relationships, and in Vivo Evaluations of Substituted Di-tert-butylphenols as a Novel Class of Potent, Selective, and Orally Active Cyclooxygenase-2 Inhibitors. 1. Thiazolone and Oxazolone Series
Song, Yuntao, Connor, David T, Doubleday, Robert, Sorenson, Roderick J, Sercel, Anthony D, Unangst, Paul C, Roth, Bruce D, Gilbertsen, Richard B, Chan, Kam, Schrier, Denis J, Guglietta, Antonio, Bornemeier, Dirk A, Dyer, Richard D
Published in Journal of medicinal chemistry (08.04.1999)
Published in Journal of medicinal chemistry (08.04.1999)
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Journal Article
Anti-inflammatory properties of Gö 6850: a selective inhibitor of protein kinase C
Jacobson, P B, Kuchera, S L, Metz, A, Schächtele, C, Imre, K, Schrier, D J
Published in The Journal of pharmacology and experimental therapeutics (01.11.1995)
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Published in The Journal of pharmacology and experimental therapeutics (01.11.1995)
Journal Article
Expression of lung vascular and airway ICAM-1 after exposure to bacterial lipopolysaccharide
Beck-Schimmer, B, Schimmer, RC, Warner, RL, Schmal, H, Nordblom, G, Flory, CM, Lesch, ME, Friedl, HP, Schrier, DJ, Ward, PA
Published in American journal of respiratory cell and molecular biology (01.09.1997)
Published in American journal of respiratory cell and molecular biology (01.09.1997)
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Role of angiotensin-converting enzyme in Bacille Calmette-Guérin-induced granulomatous inflammation. Increased angiotensin-converting enzyme levels in lung lavage and suppression of inflammation with captopril
Schrier, D J, Ripani, L M, Katzenstein, A L, Moore, V L
Published in The Journal of clinical investigation (01.03.1982)
Published in The Journal of clinical investigation (01.03.1982)
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