A Binary Bivalent Supramolecular Assembly Platform Based on Cucurbit[8]uril and Dimeric Adapter Protein 14‐3‐3
de Vink, Pim J., Briels, Jeroen M., Schrader, Thomas, Milroy, Lech‐Gustav, Brunsveld, Luc, Ottmann, Christian
Published in Angewandte Chemie International Edition (24.07.2017)
Published in Angewandte Chemie International Edition (24.07.2017)
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The Molecular Tweezer CLR01 Stabilizes a Disordered Protein–Protein Interface
Bier, David, Mittal, Sumit, Bravo-Rodriguez, Kenny, Sowislok, Andrea, Guillory, Xavier, Briels, Jeroen, Heid, Christian, Bartel, Maria, Wettig, Burkhard, Brunsveld, Luc, Sanchez-Garcia, Elsa, Schrader, Thomas, Ottmann, Christian
Published in Journal of the American Chemical Society (15.11.2017)
Published in Journal of the American Chemical Society (15.11.2017)
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CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson’s disease
Bengoa-Vergniory, Nora, Faggiani, Emilie, Ramos-Gonzalez, Paula, Kirkiz, Ecem, Connor-Robson, Natalie, Brown, Liam V., Siddique, Ibrar, Li, Zizheng, Vingill, Siv, Cioroch, Milena, Cavaliere, Fabio, Threlfell, Sarah, Roberts, Bradley, Schrader, Thomas, Klärner, Frank-Gerrit, Cragg, Stephanie, Dehay, Benjamin, Bitan, Gal, Matute, Carlos, Bezard, Erwan, Wade-Martins, Richard
Published in Nature communications (28.09.2020)
Published in Nature communications (28.09.2020)
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Metabolic shift toward oxidative phosphorylation in docetaxel resistant prostate cancer cells
Ippolito, Luigi, Marini, Alberto, Cavallini, Lorenzo, Morandi, Andrea, Pietrovito, Laura, Pintus, Gianfranco, Giannoni, Elisa, Schrader, Thomas, Puhr, Martin, Chiarugi, Paola, Taddei, Maria Letizia
Published in Oncotarget (20.09.2016)
Published in Oncotarget (20.09.2016)
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Lysine-Specific Molecular Tweezers Are Broad-Spectrum Inhibitors of Assembly and Toxicity of Amyloid Proteins
Sinha, Sharmistha, Lopes, Dahabada H. J, Du, Zhenming, Pang, Eric S, Shanmugam, Akila, Lomakin, Aleksey, Talbiersky, Peter, Tennstaedt, Annette, McDaniel, Kirsten, Bakshi, Reena, Kuo, Pei-Yi, Ehrmann, Michael, Benedek, George B, Loo, Joseph A, Klärner, Frank-Gerrit, Schrader, Thomas, Wang, Chunyu, Bitan, Gal
Published in Journal of the American Chemical Society (26.10.2011)
Published in Journal of the American Chemical Society (26.10.2011)
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A tribute to Carsten Schmuck
Niemeyer, Jochen, Piantanida, Ivo, Schrader, Thomas
Published in Beilstein journal of organic chemistry (29.11.2021)
Published in Beilstein journal of organic chemistry (29.11.2021)
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Anti-amyloid treatment is broadly effective in neuronopathic mucopolysaccharidoses and synergizes with gene therapy in MPS-IIIA
Giaccio, Marianna, Monaco, Antonio, Galiano, Laura, Parente, Andrea, Borzacchiello, Luigi, Rubino, Riccardo, Klärner, Frank-Gerrit, Killa, Dennis, Perna, Claudia, Piccolo, Pasquale, Marotta, Marcello, Pan, Xuefang, Khijniak, Marie, Siddique, Ibrar, Schrader, Thomas, Pshezhetsky, Alexey V., Sorrentino, Nicolina Cristina, Bitan, Gal, Fraldi, Alessandro
Published in Molecular therapy (06.11.2024)
Published in Molecular therapy (06.11.2024)
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Inhibition of Staphylococcus aureus biofilm-forming functional amyloid by molecular tweezers
Malishev, Ravit, Salinas, Nir, Gibson, James, Eden, Angela Bailey, Mieres-Perez, Joel, Ruiz-Blanco, Yasser B., Malka, Orit, Kolusheva, Sofiya, Klärner, Frank-Gerrit, Schrader, Thomas, Sanchez-Garcia, Elsa, Wang, Chunyu, Landau, Meytal, Bitan, Gal, Jelinek, Raz
Published in Cell chemical biology (16.09.2021)
Published in Cell chemical biology (16.09.2021)
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Discovery of a brain penetrant small molecule antagonist targeting LPA1 receptors to reduce neuroinflammation and promote remyelination in multiple sclerosis
Poon, Michael M., Lorrain, Kym I., Stebbins, Karin J., Edu, Geraldine C., Broadhead, Alexander R., Lorenzana, Ariana O., Paulson, Bryanna E., Baccei, Christopher S., Roppe, Jeffrey R., Schrader, Thomas O., Valdez, Lino J., Xiong, Yifeng, Chen, Austin C., Lorrain, Daniel S.
Published in Scientific reports (08.05.2024)
Published in Scientific reports (08.05.2024)
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The molecular tweezer CLR01 inhibits aberrant superoxide dismutase 1 (SOD1) self-assembly in vitro and in the G93A-SOD1 mouse model of ALS
Malik, Ravinder, Meng, Helen, Wongkongkathep, Piriya, Corrales, Christian I., Sepanj, Niki, Atlasi, Ryan S., Klärner, Frank-Gerrit, Schrader, Thomas, Spencer, Melissa J., Loo, Joseph A., Wiedau, Martina, Bitan, Gal
Published in The Journal of biological chemistry (08.03.2019)
Published in The Journal of biological chemistry (08.03.2019)
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Molecular Clip and Tweezer Introduce New Mechanisms of Enzyme Inhibition
Talbiersky, Peter, Bastkowski, Frank, Klärner, Frank-Gerrit, Schrader, Thomas
Published in Journal of the American Chemical Society (30.07.2008)
Published in Journal of the American Chemical Society (30.07.2008)
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Specific inhibition of the Survivin–CRM1 interaction by peptide-modified molecular tweezers
Meiners, Annika, Bäcker, Sandra, Hadrović, Inesa, Heid, Christian, Beuck, Christine, Ruiz-Blanco, Yasser B., Mieres-Perez, Joel, Pörschke, Marius, Grad, Jean-Noël, Vallet, Cecilia, Hoffmann, Daniel, Bayer, Peter, Sánchez-García, Elsa, Schrader, Thomas, Knauer, Shirley K.
Published in Nature communications (08.03.2021)
Published in Nature communications (08.03.2021)
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A Fluorescent Polymeric Heparin Sensor
Sun, Wei, Bandmann, Heinz, Schrader, Thomas
Published in Chemistry : a European journal (01.01.2007)
Published in Chemistry : a European journal (01.01.2007)
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Affinity Polymers Tailored for the Protein A Binding Site of Immunoglobulin G Proteins
Latza, Patricia, Gilles, Patrick, Schaller, Torsten, Schrader, Thomas
Published in Chemistry : a European journal (01.09.2014)
Published in Chemistry : a European journal (01.09.2014)
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Attack Detection for Medical Cyber-Physical Systems - A Systematic Literature Review
Weber, Simon, Stein, Stefan, Pilgermann, Michael, Schrader, Thomas
Published in IEEE access (01.01.2023)
Published in IEEE access (01.01.2023)
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