Evaluation of a Three-Dimensional Primary Human Hepatocyte Spheroid Model: Adoption and Industrialization for the Enhanced Detection of Drug-Induced Liver Injury
Schofield, Christopher A, Walker, Tracy M, Taylor, Maxine A, Patel, Metul, Vlachou, Denise F, Macina, Justyna M, Vidgeon-Hart, Martin P, Williams, Ann, McGill, Paul J, Newman, Carla F, Sakatis, Melanie Z
Published in Chemical research in toxicology (20.12.2021)
Published in Chemical research in toxicology (20.12.2021)
Get full text
Journal Article
A Scalable 3D High-Content Imaging Protocol for Measuring a Drug Induced DNA Damage Response Using Immunofluorescent Subnuclear γH2AX Spots in Patient Derived Ovarian Cancer Organoids
Keles, Hakan, Schofield, Christopher A., Rannikmae, Helena, Edwards, Erin Elizabeth, Mohamet, Lisa
Published in ACS pharmacology & translational science (13.01.2023)
Published in ACS pharmacology & translational science (13.01.2023)
Get full text
Journal Article
A multicenter assessment of single-cell models aligned to standard measures of cell health for prediction of acute hepatotoxicity
Sison-Young, Rowena L., Lauschke, Volker M., Johann, Esther, Alexandre, Eliane, Antherieu, Sébastien, Aerts, Hélène, Gerets, Helga H. J., Labbe, Gilles, Hoët, Delphine, Dorau, Martina, Schofield, Christopher A., Lovatt, Cerys A., Holder, Julie C., Stahl, Simone H., Richert, Lysiane, Kitteringham, Neil R., Jones, Robert P., Elmasry, Mohamed, Weaver, Richard J., Hewitt, Philip G., Ingelman-Sundberg, Magnus, Goldring, Chris E., Park, B. Kevin
Published in Archives of toxicology (01.03.2017)
Published in Archives of toxicology (01.03.2017)
Get full text
Journal Article
A multicenter assessment of single-cell models aligned to standard measures of cell health for prediction of acute hepatotoxicity
Sison-Young, Rowena L., Lauschke, Volker M., Johann, Esther, Alexandre, Eliane, Antherieu, Sébastien, Aerts, Hélène, Gerets, Helga H. J., Labbe, Gilles, Hoët, Delphine, Dorau, Martina, Schofield, Christopher A., Lovatt, Cerys A., Holder, Julie C., Stahl, Simone H., Richert, Lysiane, Kitteringham, Neil R., Jones, Robert P., Elmasry, Mohamed, Weaver, Richard J., Hewitt, Philip G., Ingelman-Sundberg, Magnus, Goldring, Chris E., Park, B. Kevin
Published in Archives of toxicology (01.03.2017)
Published in Archives of toxicology (01.03.2017)
Get full text
Journal Article
A Scalable 3D High-Content Imaging Protocol for Measuring a Drug Induced DNA Damage Response Using Immunofluorescent Sub-nuclear γH2AX Spots in Patient Derived Ovarian Cancer Organoids
Keles, Hakan, Schofield, Christopher A, Rannikmae, Helena, Edwards, Erin Elizabeth, Mohamet, Lisa
Published in bioRxiv (19.09.2022)
Published in bioRxiv (19.09.2022)
Get full text
Paper
JMJD6 targeting agents for treatment of prostate cancer
SHARPE ADAM, TOMBIN ANTHONY, ISLAM MD SAIFUL, DEBONO JOHN, WELTY JONATHAN, PLIMATE, STEPHEN, PASKALIS, ALEC, SCHOFIELD, CHRISTOPHER
Year of Publication 03.11.2023
Get full text
Year of Publication 03.11.2023
Patent
METHOD OF OPERATING AN ANALYTICAL LABORATORY
SCHOFIELD CHRISTOPHER, GULIAS CARLOS FERNANDEZ, CHOTZIDIS ANGELOS, SMIT WERNER, VON HOPFFGARTEN MORITZ, ARNOLD DANIEL, RAUSCHER FLORIAN REINHARD, TAN CHYE YIN PRISCILLA
Year of Publication 25.08.2020
Get full text
Year of Publication 25.08.2020
Patent
INHIBITORS OF METALLO-BETA-LACTAMASES
JONES PHILIP, RYDZIK ANNA M, HEWITT JOANNE, SCHOFIELD CHRISTOPHER J, PANNIFER ANDREW, BREM JURGEN, MCDONOUGH MICHAEL A, MORRISON ANGUS
Year of Publication 28.09.2018
Get full text
Year of Publication 28.09.2018
Patent
A method for assaying FTO (2-oxoglutarate dependent oxygenase) activity
GERKEN THOMAS, PONTING CHRISTOPHER PAUL, SCHOFIELD CHRISTOPHER JOSEPH, ASHCROFT FRANCES MARY
Year of Publication 06.10.2010
Get full text
Year of Publication 06.10.2010
Patent
Hif hydroxylase inhibitors
PUGH CHRISTOPHER WILLIAM, RATCLIFFE PETER JOHN, SCHOFIELD CHRISTOPHER JOSEPH, MAXWELL PATRICK HENRY
Year of Publication 18.06.2008
Get full text
Year of Publication 18.06.2008
Patent
Hif hydroxylase inhibitors
PUGH CHRISTOPHER WILLIAM, RATCLIFFE PETER JOHN, SCHOFIELD CHRISTOPHER JOSEPH, MAXWELL PATRICK HENRY
Year of Publication 18.06.2008
Get full text
Year of Publication 18.06.2008
Patent
HIF hydroxylase inhibitors
PUGH CHRISTOPHER WILLIAM, RATCLIFFE PETER JOHN, SCHOFIELD CHRISTOPHER JOSEPH, MAXWELL PATRICK HENRY
Year of Publication 18.06.2008
Get full text
Year of Publication 18.06.2008
Patent
Hif hydroxylase inhibitors
PUGH CHRISTOPHER WILLIAM, RATCLIFFE PETER JOHN, SCHOFIELD CHRISTOPHER JOSEPH, MAXWELL PATRICK HENRY
Year of Publication 18.06.2008
Get full text
Year of Publication 18.06.2008
Patent
Hif hydroxylase inhibitors
PUGH CHRISTOPHER WILLIAM, RATCLIFFE PETER JOHN, SCHOFIELD CHRISTOPHER JOSEPH, MAXWELL PATRICK HENRY
Year of Publication 18.06.2008
Get full text
Year of Publication 18.06.2008
Patent
HIF hydroxylase inhibitors
PUGH CHRISTOPHER WILLIAM, RATCLIFFE PETER JOHN, SCHOFIELD CHRISTOPHER JOSEPH, MAXWELL PATRICK HENRY
Year of Publication 20.02.2008
Get full text
Year of Publication 20.02.2008
Patent