2-Oxoglutarate-Dependent Oxygenases
Islam, Md. Saiful, Leissing, Thomas M, Chowdhury, Rasheduzzaman, Hopkinson, Richard J, Schofield, Christopher J
Published in Annual review of biochemistry (20.06.2018)
Published in Annual review of biochemistry (20.06.2018)
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Synthesis of meta-substituted arene bioisosteres from [3.1.1]propellane
Frank, Nils, Nugent, Jeremy, Shire, Bethany R., Pickford, Helena D., Rabe, Patrick, Sterling, Alistair J., Zarganes-Tzitzikas, Tryfon, Grimes, Thomas, Thompson, Amber L., Smith, Russell C., Schofield, Christopher J., Brennan, Paul E., Duarte, Fernanda, Anderson, Edward A.
Published in Nature (London) (24.11.2022)
Published in Nature (London) (24.11.2022)
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Mechanisms of human histone and nucleic acid demethylases
Walport, Louise J, Hopkinson, Richard J, Schofield, Christopher J
Published in Current opinion in chemical biology (01.12.2012)
Published in Current opinion in chemical biology (01.12.2012)
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Journal Article
Recent Progress in Histone Demethylase Inhibitors
McAllister, Tom E, England, Katherine S, Hopkinson, Richard J, Brennan, Paul E, Kawamura, Akane, Schofield, Christopher J
Published in Journal of medicinal chemistry (25.02.2016)
Published in Journal of medicinal chemistry (25.02.2016)
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Journal Article
The oxygenase Jmjd6--a case study in conflicting assignments
Böttger, Angelika, Islam, Md Saiful, Chowdhury, Rasheduzzaman, Schofield, Christopher J, Wolf, Alexander
Published in Biochemical journal (01.06.2015)
Published in Biochemical journal (01.06.2015)
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Journal Article
Structure–function relationships of human JmjC oxygenases—demethylases versus hydroxylases
Markolovic, Suzana, Leissing, Thomas M, Chowdhury, Rasheduzzaman, Wilkins, Sarah E, Lu, Xin, Schofield, Christopher J
Published in Current opinion in structural biology (01.12.2016)
Published in Current opinion in structural biology (01.12.2016)
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Journal Article
Structural basis of metallo-β-lactamase, serine-β-lactamase and penicillin-binding protein inhibition by cyclic boronates
Brem, Jürgen, Cain, Ricky, Cahill, Samuel, McDonough, Michael A, Clifton, Ian J, Jiménez-Castellanos, Juan-Carlos, Avison, Matthew B, Spencer, James, Fishwick, Colin W G, Schofield, Christopher J
Published in Nature communications (08.08.2016)
Published in Nature communications (08.08.2016)
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Journal Article
MeDBA: the Metalloenzyme Data Bank and Analysis platform
Yu, Jun-Lin, Wu, Song, Zhou, Cong, Dai, Qing-Qing, Schofield, Christopher J, Li, Guo-Bo
Published in Nucleic acids research (06.01.2023)
Published in Nucleic acids research (06.01.2023)
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Characterization of the SARS-CoV-2 ExoN (nsp14ExoN–nsp10) complex: implications for its role in viral genome stability and inhibitor identification
Baddock, Hannah T, Brolih, Sanja, Yosaatmadja, Yuliana, Ratnaweera, Malitha, Bielinski, Marcin, Swift, Lonnie P, Cruz-Migoni, Abimael, Fan, Haitian, Keown, Jeremy R, Walker, Alexander P, Morris, Garrett M, Grimes, Jonathan M, Fodor, Ervin, Schofield, Christopher J, Gileadi, Opher, McHugh, Peter J
Published in Nucleic acids research (22.02.2022)
Published in Nucleic acids research (22.02.2022)
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Journal Article
DNA Modification under Mild Conditions by Suzuki-Miyaura Cross-Coupling for the Generation of Functional Probes
Lercher, Lukas, McGouran, Joanna F., Kessler, Benedikt M., Schofield, Christopher J., Davis, Benjamin G.
Published in Angewandte Chemie (International ed.) (27.09.2013)
Published in Angewandte Chemie (International ed.) (27.09.2013)
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Journal Article
Catalysis by the Non-Heme Iron(II) Histone Demethylase PHF8 Involves Iron Center Rearrangement and Conformational Modulation of Substrate Orientation
Chaturvedi, Shobhit S, Ramanan, Rajeev, Lehnert, Nicolai, Schofield, Christopher J, Karabencheva-Christova, Tatyana G, Christov, Christo Z
Published in ACS catalysis (17.01.2020)
Published in ACS catalysis (17.01.2020)
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Journal Article
Highly selective inhibition of histone demethylases by de novo macrocyclic peptides
Kawamura, Akane, Münzel, Martin, Kojima, Tatsuya, Yapp, Clarence, Bhushan, Bhaskar, Goto, Yuki, Tumber, Anthony, Katoh, Takayuki, King, Oliver N F, Passioura, Toby, Walport, Louise J, Hatch, Stephanie B, Madden, Sarah, Müller, Susanne, Brennan, Paul E, Chowdhury, Rasheduzzaman, Hopkinson, Richard J, Suga, Hiroaki, Schofield, Christopher J
Published in Nature communications (06.04.2017)
Published in Nature communications (06.04.2017)
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