Evaluation of off-target and on-target scoring algorithms and integration into the guide RNA selection tool CRISPOR
Haeussler, Maximilian, Schönig, Kai, Eckert, Hélène, Eschstruth, Alexis, Mianné, Joffrey, Renaud, Jean-Baptiste, Schneider-Maunoury, Sylvie, Shkumatava, Alena, Teboul, Lydia, Kent, Jim, Joly, Jean-Stephane, Concordet, Jean-Paul
Published in Genome Biology (05.07.2016)
Published in Genome Biology (05.07.2016)
Get full text
Journal Article
mTOR inhibitor reverses autistic-like social deficit behaviours in adult rats with both Tsc2 haploinsufficiency and developmental status epilepticus
Schneider, Miriam, de Vries, Petrus J., Schönig, Kai, Rößner, Veit, Waltereit, Robert
Published in European archives of psychiatry and clinical neuroscience (01.08.2017)
Published in European archives of psychiatry and clinical neuroscience (01.08.2017)
Get full text
Journal Article
The potential for beta-structure in the repeat domain of tau protein determines aggregation, synaptic decay, neuronal loss, and coassembly with endogenous Tau in inducible mouse models of tauopathy
Mocanu, Maria-Magdalena, Nissen, Astrid, Eckermann, Katrin, Khlistunova, Inna, Biernat, Jacek, Drexler, Dagmar, Petrova, Olga, Schönig, Kai, Bujard, Hermann, Mandelkow, Eckhard, Zhou, Lepu, Rune, Gabriele, Mandelkow, Eva-Maria
Published in The Journal of neuroscience (16.01.2008)
Published in The Journal of neuroscience (16.01.2008)
Get full text
Journal Article
Defective glycosylation of coagulation factor XII underlies hereditary angioedema type III
Björkqvist, Jenny, de Maat, Steven, Lewandrowski, Urs, Di Gennaro, Antonio, Oschatz, Chris, Schönig, Kai, Nöthen, Markus M, Drouet, Christian, Braley, Hal, Nolte, Marc W, Sickmann, Albert, Panousis, Con, Maas, Coen, Renné, Thomas
Published in The Journal of clinical investigation (01.08.2015)
Published in The Journal of clinical investigation (01.08.2015)
Get full text
Journal Article
Losing Control: Excessive Alcohol Seeking after Selective Inactivation of Cue-Responsive Neurons in the Infralimbic Cortex
Pfarr, Simone, Meinhardt, Marcus W, Klee, Manuela L, Hansson, Anita C, Vengeliene, Valentina, Schönig, Kai, Bartsch, Dusan, Hope, Bruce T, Spanagel, Rainer, Sommer, Wolfgang H
Published in The Journal of neuroscience (29.07.2015)
Published in The Journal of neuroscience (29.07.2015)
Get full text
Journal Article
A progressive dopaminergic phenotype associated with neurotoxic conversion of α-synuclein in BAC-transgenic rats
NUBER, Silke, HARMUTH, Florian, CALAMINUS, Carsten, PICHLER, Bernd J, JENSEN, Poul H, MÜLLER, Christian P, AMATO, Davide, KORNHUBER, Johannes, TEISMANN, Peter, YAMAKADO, Hodaka, TAKAHASHI, Ryosuke, WINKLER, Juergen, KOHL, Zacharias, MASLIAH, Eliezer, RIESS, Olaf, ADAME, Anthony, TREJO, Margaritha, SCHÖNIG, Kai, ZIMMERMANN, Frank, BAUER, Claudia, CASADEI, Nicolas, GIEL, Christiane
Published in Brain (London, England : 1878) (01.02.2013)
Published in Brain (London, England : 1878) (01.02.2013)
Get full text
Journal Article
An analgesic pathway from parvocellular oxytocin neurons to the periaqueductal gray in rats
Iwasaki, Mai, Lefevre, Arthur, Althammer, Ferdinand, Clauss Creusot, Etienne, Łąpieś, Olga, Petitjean, Hugues, Hilfiger, Louis, Kerspern, Damien, Melchior, Meggane, Küppers, Stephanie, Krabichler, Quirin, Patwell, Ryan, Kania, Alan, Gruber, Tim, Kirchner, Matthew K., Wimmer, Moritz, Fröhlich, Henning, Dötsch, Laura, Schimmer, Jonas, Herpertz, Sabine C., Ditzen, Beate, Schaaf, Christian P., Schönig, Kai, Bartsch, Dusan, Gugula, Anna, Trenk, Aleksandra, Blasiak, Anna, Stern, Javier E., Darbon, Pascal, Grinevich, Valery, Charlet, Alexandre
Published in Nature communications (24.02.2023)
Published in Nature communications (24.02.2023)
Get full text
Journal Article
Deletion of psychiatric risk gene Cacna1c impairs hippocampal neurogenesis in cell‐autonomous fashion
Völkening, Bianca, Schönig, Kai, Kronenberg, Golo, Bartsch, Dusan, Weber, Tillmann
Published in Glia (01.05.2017)
Published in Glia (01.05.2017)
Get full text
Journal Article
Altered PVN‐to‐CA2 hippocampal oxytocin pathway and reduced number of oxytocin‐receptor expressing astrocytes in heart failure rats
Althammer, Ferdinand, Roy, Ranjan K., Lefevre, Arthur, Najjar, Rami S., Schoenig, Kai, Bartsch, Dusan, Eliava, Marina, Feresin, Rafaela G., Hammock, Elizabeth A. D., Murphy, Anne Z., Charlet, Alexandre, Grinevich, Valery, Stern, Javier E.
Published in Journal of neuroendocrinology (01.07.2022)
Published in Journal of neuroendocrinology (01.07.2022)
Get full text
Journal Article
A Clathrin light chain A reporter mouse for in vivo imaging of endocytosis
Grimm, Elisabeth, van der Hoeven, Franciscus, Sardella, Donato, Willig, Katrin I, Engel, Ulrike, Veits, Nisha, Engel, Robert, Cavalcanti-Adam, Elisabetta Ada, Bestvater, Felix, Bordoni, Luca, Jennemann, Richard, Schönig, Kai, Schiessl, Ina Maria, Sandhoff, Roger
Published in PloS one (23.09.2022)
Published in PloS one (23.09.2022)
Get full text
Journal Article
An efficient and versatile system for acute and chronic modulation of renal tubular function in transgenic mice
Koesters, Robert, Traykova-Brauch, Milena, Schönig, Kai, Greiner, Oliver, Miloud, Tewfik, Jauch, Anna, Bode, Manja, Felsher, Dean W, Glick, Adam B, Kwiatkowski, David J, Bujard, Hermann, Horst, Jürgen, von Knebel Doeberitz, Magnus, Niggli, Felix K, Kriz, Wilhelm, Gröne, Hermann-Josef
Published in Nature medicine (01.09.2008)
Published in Nature medicine (01.09.2008)
Get full text
Journal Article
Differential Roles for L-Type Calcium Channel Subtypes in Alcohol Dependence
Uhrig, Stefanie, Vandael, David, Marcantoni, Andrea, Dedic, Nina, Bilbao, Ainhoa, Vogt, Miriam A, Hirth, Natalie, Broccoli, Laura, Bernardi, Rick E, Schönig, Kai, Gass, Peter, Bartsch, Dusan, Spanagel, Rainer, Deussing, Jan M, Sommer, Wolfgang H, Carbone, Emilio, Hansson, Anita C
Published in Neuropsychopharmacology (New York, N.Y.) (01.04.2017)
Published in Neuropsychopharmacology (New York, N.Y.) (01.04.2017)
Get full text
Journal Article
The β-Propensity of Tau Determines Aggregation and Synaptic Loss in Inducible Mouse Models of Tauopathy
Eckermann, Katrin, Mocanu, Maria-Magdalena, Khlistunova, Inna, Biernat, Jacek, Nissen, Astrid, Hofmann, Anne, Schönig, Kai, Bujard, Hermann, Haemisch, Andreas, Mandelkow, Eckhard, Zhou, Lepu, Rune, Gabriele, Mandelkow, Eva-Maria
Published in The Journal of biological chemistry (26.10.2007)
Published in The Journal of biological chemistry (26.10.2007)
Get full text
Journal Article
CRISPR-Cas9 mediated generation of a conditional poly(A) binding protein nuclear 1 (Pabpn1) mouse model reveals an essential role for hematopoietic stem cells
Sommerkamp, Pia, Sommerkamp, Alexander C., Zeisberger, Petra, Eiben, Paula Leonie, Narr, Andreas, Korkmaz, Aylin, Przybylla, Adriana, Sohn, Markus, van der Hoeven, Franciscus, Schönig, Kai, Trumpp, Andreas
Published in Scientific reports (03.05.2022)
Published in Scientific reports (03.05.2022)
Get full text
Journal Article
Hyperoxia but not AOX expression mitigates pathological cardiac remodeling in a mouse model of inflammatory cardiomyopathy
Dhandapani, Praveen K., Begines-Moreno, Isabel M., Brea-Calvo, Gloria, Gärtner, Ulrich, Graeber, Thomas G., Javier Sanchez, Gerardo, Morty, Rory E., Schönig, Kai, Hoeve, Johanna ten, Wietelmann, Astrid, Braun, Thomas, Jacobs, Howard T., Szibor, Marten
Published in Scientific reports (04.09.2019)
Published in Scientific reports (04.09.2019)
Get full text
Journal Article
Forebrain-specific, conditional silencing of Staufen2 alters synaptic plasticity, learning, and memory in rats
Berger, Stefan M, Fernández-Lamo, Iván, Schönig, Kai, Fernández Moya, Sandra M, Ehses, Janina, Schieweck, Rico, Clementi, Stefano, Enkel, Thomas, Grothe, Sascha, von Bohlen Und Halbach, Oliver, Segura, Inmaculada, Delgado-García, José María, Gruart, Agnès, Kiebler, Michael A, Bartsch, Dusan
Published in Genome Biology (17.11.2017)
Published in Genome Biology (17.11.2017)
Get full text
Journal Article
Inducible knockdown of procollagen I protects mice from liver fibrosis and leads to dysregulated matrix genes and attenuated inflammation
Molokanova, Olena, Schönig, Kai, Weng, Shih-Yen, Wang, Xiaoyu, Bros, Matthias, Diken, Mustafa, Ohngemach, Svetlana, Karsdal, Morten, Strand, Dennis, Nikolaev, Alexei, Eshkind, Leonid, Schuppan, Detlef
Published in Matrix biology (01.03.2018)
Published in Matrix biology (01.03.2018)
Get full text
Journal Article