Increased 4R-Tau Induces Pathological Changes in a Human-Tau Mouse Model
Schoch, Kathleen M., DeVos, Sarah L., Miller, Rebecca L., Chun, Seung J., Norrbom, Michaela, Wozniak, David F., Dawson, Hana N., Bennett, C. Frank, Rigo, Frank, Miller, Timothy M.
Published in Neuron (Cambridge, Mass.) (01.06.2016)
Published in Neuron (Cambridge, Mass.) (01.06.2016)
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Journal Article
Targeted ASO-mediated Atp1a2 knockdown in astrocytes reduces SOD1 aggregation and accelerates disease onset in mutant SOD1 mice
Iyer, Abhirami K, Schoch, Kathleen M, Verbeck, Anthony, Galasso, Grant, Chen, Hao, Smith, Sarah, Oldenborg, Anna, Miller, Timothy M, Karch, Celeste M, Bonni, Azad
Published in PloS one (28.11.2023)
Published in PloS one (28.11.2023)
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Journal Article
Calpains mediate axonal cytoskeleton disintegration during Wallerian degeneration
Ma, Marek, Ferguson, Toby A, Schoch, Kathleen M, Li, Jian, Qian, Yaping, Shofer, Frances S, Saatman, Kathryn E, Neumar, Robert W
Published in Neurobiology of disease (01.08.2013)
Published in Neurobiology of disease (01.08.2013)
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Journal Article
Astrocytic 4R tau expression drives astrocyte reactivity and dysfunction
Ezerskiy, Lubov A, Schoch, Kathleen M, Sato, Chihiro, Beltcheva, Mariana, Horie, Kanta, Rigo, Frank, Martynowicz, Ryan, Karch, Celeste M, Bateman, Randall J, Miller, Timothy M
Published in JCI insight (11.01.2022)
Published in JCI insight (11.01.2022)
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Journal Article
Genetic Manipulation of Cell Death and Neuroplasticity Pathways in Traumatic Brain Injury
Schoch, Kathleen M., Madathil, Sindhu K., Saatman, Kathryn E.
Published in Neurotherapeutics (01.04.2012)
Published in Neurotherapeutics (01.04.2012)
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Journal Article
Antisense Oligonucleotides for the Study and Treatment of ALS
Boros, Benjamin D., Schoch, Kathleen M., Kreple, Collin J., Miller, Timothy M.
Published in Neurotherapeutics (01.07.2022)
Published in Neurotherapeutics (01.07.2022)
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Journal Article
Tau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy
DeVos, Sarah L, Miller, Rebecca L, Schoch, Kathleen M, Holmes, Brandon B, Kebodeaux, Carey S, Wegener, Amy J, Chen, Guo, Shen, Tao, Tran, Hien, Nichols, Brandon, Zanardi, Tom A, Kordasiewicz, Holly B, Swayze, Eric E, Bennett, C Frank, Diamond, Marc I, Miller, Timothy M
Published in Science translational medicine (25.01.2017)
Published in Science translational medicine (25.01.2017)
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Journal Article
Acute Trem2 reduction triggers increased microglial phagocytosis, slowing amyloid deposition in mice
Schoch, Kathleen M., Ezerskiy, Lubov A., Morhaus, Michaela M., Bannon, Riley N., Sauerbeck, Andrew D., Shabsovich, Mark, Jafar-nejad, Paymaan, Rigo, Frank, Miller, Timothy M.
Published in Proceedings of the National Academy of Sciences - PNAS (06.07.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (06.07.2021)
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Journal Article
Is presymptomatic ALS perivascular?
Kreple, Collin J., Schoch, Kathleen M., Miller, Timothy M.
Published in Nature medicine (01.04.2021)
Published in Nature medicine (01.04.2021)
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Journal Article
Improving scientific communication with service, education and career development
Dicks, Amanda, Bhatia, Himanshi, Clemens, Adam W., Locke, Marissa C., Mueller, Elizabeth A., Murphy, Daniel, Pomper, Nathan, Robinson, Anne E., Schoch, Kathleen M.
Published in Nature biotechnology (01.10.2021)
Published in Nature biotechnology (01.10.2021)
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Journal Article
MicroRNA Profiling Reveals Marker of Motor Neuron Disease in ALS Models
Hoye, Mariah L, Koval, Erica D, Wegener, Amy J, Hyman, Theodore S, Yang, Chengran, O'Brien, David R, Miller, Rebecca L, Cole, Tracy, Schoch, Kathleen M, Shen, Tao, Kunikata, Tomonori, Richard, Jean-Philippe, Gutmann, David H, Maragakis, Nicholas J, Kordasiewicz, Holly B, Dougherty, Joseph D, Miller, Timothy M
Published in The Journal of neuroscience (31.05.2017)
Published in The Journal of neuroscience (31.05.2017)
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Journal Article
Synthesis and in vitro characterization of a P2X7 radioligand [123I]TZ6019 and its response to neuroinflammation in a mouse model of Alzheimer disease
Jin, Hongjun, Han, Junbin, Resing, Derek, Liu, Hui, Yue, Xuyi, Miller, Rebecca L., Schoch, Kathleen M., Miller, Timothy M., Perlmutter, Joel S., Egan, Terrance M., Tu, Zhude
Published in European journal of pharmacology (05.02.2018)
Published in European journal of pharmacology (05.02.2018)
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Journal Article
TREM2 inhibition triggers antitumor cell activity of myeloid cells in glioblastoma
Sun, Rui, Han, Rowland, McCornack, Colin, Khan, Saad, Tabor, G Travis, Chen, Yun, Hou, Jinchao, Jiang, Haowu, Schoch, Kathleen M, Mao, Diane D, Cleary, Ryan, Yang, Alicia, Liu, Qin, Luo, Jingqin, Petti, Allegra, Miller, Timothy M, Ulrich, Jason D, Holtzman, David M, Kim, Albert H
Published in Science advances (12.05.2023)
Published in Science advances (12.05.2023)
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Journal Article
Antisense oligonucleotides extend survival and reverse decrement in muscle response in ALS models
McCampbell, Alex, Cole, Tracy, Wegener, Amy J, Tomassy, Giulio S, Setnicka, Amy, Farley, Brandon J, Schoch, Kathleen M, Hoye, Mariah L, Shabsovich, Mark, Sun, Linhong, Luo, Yi, Zhang, Mingdi, Comfort, Nicole, Wang, Bin, Amacker, Jessica, Thankamony, Sai, Salzman, David W, Cudkowicz, Merit, Graham, Danielle L, Bennett, C Frank, Kordasiewicz, Holly B, Swayze, Eric E, Miller, Timothy M
Published in The Journal of clinical investigation (01.08.2018)
Published in The Journal of clinical investigation (01.08.2018)
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Journal Article
Calpastatin overexpression limits calpain-mediated proteolysis and behavioral deficits following traumatic brain injury
Schoch, Kathleen M., Evans, Heather N., Brelsfoard, Jennifer M., Madathil, Sindhu K., Takano, Jiro, Saido, Takaomi C., Saatman, Kathryn E.
Published in Experimental neurology (01.08.2012)
Published in Experimental neurology (01.08.2012)
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Journal Article
TSC1 loss increases risk for tauopathy by inducing tau acetylation and preventing tau clearance via chaperone-mediated autophagy
Alquezar, Carolina, Schoch, Kathleen M, Geier, Ethan G, Ramos, Eliana Marisa, Scrivo, Aurora, Li, Kathy H, Argouarch, Andrea R, Mlynarski, Elisabeth E, Dombroski, Beth, DeTure, Michael, Dickson, Dennis W, Yokoyama, Jennifer S, Cuervo, Ana M, Burlingame, Alma L, Schellenberg, Gerard D, Miller, Timothy M, Miller, Bruce L, Kao, Aimee W
Published in Science advances (05.11.2021)
Published in Science advances (05.11.2021)
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Journal Article