Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia
Konopleva, Marina, Contractor, Rooha, Tsao, Twee, Samudio, Ismael, Ruvolo, Peter P., Kitada, Shinichi, Deng, Xingming, Zhai, Dayong, Shi, Yue-Xi, Sneed, Thomas, Verhaegen, Monique, Soengas, Maria, Ruvolo, Vivian R., McQueen, Teresa, Schober, Wendy D., Watt, Julie C., Jiffar, Tilahun, Ling, Xiaoyang, Marini, Frank C., Harris, David, Dietrich, Martin, Estrov, Zeev, McCubrey, James, May, W. Stratford, Reed, John C., Andreeff, Michael
Published in Cancer cell (01.11.2006)
Published in Cancer cell (01.11.2006)
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Triptolide induces caspase-dependent cell death mediated via the mitochondrial pathway in leukemic cells
Carter, Bing Z., Mak, Duncan H., Schober, Wendy D., McQueen, Teresa, Harris, David, Estrov, Zeev, Evans, Randall L., Andreeff, Michael
Published in Blood (15.07.2006)
Published in Blood (15.07.2006)
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Triptolide sensitizes AML cells to TRAIL-induced apoptosis via decrease of XIAP and p53-mediated increase of DR5
Carter, Bing Z., Mak, Duncan H., Schober, Wendy D., Dietrich, Martin F., Pinilla, Clemencia, Vassilev, Lyubomir T., Reed, John C., Andreeff, Michael
Published in Blood (01.04.2008)
Published in Blood (01.04.2008)
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Targeting of BMI-1 expression by the novel small molecule PTC596 in mantle cell lymphoma
Maeda, Aya, Nishida, Yuki, Weetall, Marla, Cao, Liangxian, Branstrom, Arthur, Ishizawa, Jo, Nii, Takenobu, Schober, Wendy D, Abe, Yoshiaki, Matsue, Kosei, Yoshimura, Mariko, Kimura, Shinya, Kojima, Kensuke
Published in Oncotarget (19.06.2018)
Published in Oncotarget (19.06.2018)
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Simultaneous activation of p53 and inhibition of XIAP enhance the activation of apoptosis signaling pathways in AML
Carter, Bing Z., Mak, Duncan H., Schober, Wendy D., Koller, Erich, Pinilla, Clemencia, Vassilev, Lyubomir T., Reed, John C., Andreeff, Michael
Published in Blood (14.01.2010)
Published in Blood (14.01.2010)
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Concomitant Inhibition of MDM2 and Bcl-2 Protein Function Synergistically Induce Mitochondrial Apoptosis in AML
Kojima, Kensuke, Konopleva, Marina, Samudio, Ismael J, Schober, Wendy D, Bornmann, William, Andreeff, Michael
Published in Cell cycle (Georgetown, Tex.) (01.12.2006)
Published in Cell cycle (Georgetown, Tex.) (01.12.2006)
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Up-regulation of MDR1 and induction of doxorubicin resistance by histone deacetylase inhibitor depsipeptide (FK228) and ATRA in acute promyelocytic leukemia cells
Tabe, Yoko, Konopleva, Marina, Contractor, Rooha, Munsell, Mark, Schober, Wendy D., Jin, Linhua, Tsutsumi-Ishii, Yuko, Nagaoka, Isao, Igari, Jun, Andreeff, Michael
Published in Blood (15.02.2006)
Published in Blood (15.02.2006)
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Small-molecule XIAP inhibitors derepress downstream effector caspases and induce apoptosis of acute myeloid leukemia cells
Carter, Bing Z., Gronda, Marcela, Wang, Zhiliang, Welsh, Kate, Pinilla, Clemencia, Andreeff, Michael, Schober, Wendy D., Nefzi, Adel, Pond, Gregory R., Mawji, Imtiaz A., Houghten, Richard A., Ostresh, John, Brandwein, Joseph, Minden, Mark D., Schuh, Andre C., Wells, Richard A., Messner, Hans, Chun, Kathy, Reed, John C., Schimmer, Aaron D.
Published in Blood (15.05.2005)
Published in Blood (15.05.2005)
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Triptolide induces cell death independent of cellular responses to imatinib in blast crisis chronic myelogenous leukemia cells including quiescent CD34+ primitive progenitor cells
Mak, Duncan H, Schober, Wendy D, Chen, Wenjing, Konopleva, Marina, Cortes, Jorge, Kantarjian, Hagop M, Andreeff, Michael, Carter, Bing Z
Published in Molecular cancer therapeutics (01.09.2009)
Published in Molecular cancer therapeutics (01.09.2009)
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Reciprocal leukemia-stroma VCAM-1/VLA-4-dependent activation of NF-κB mediates chemoresistance
Jacamo, Rodrigo, Chen, Ye, Wang, Zhiqiang, Ma, Wencai, Zhang, Min, Spaeth, Erika L., Wang, Ying, Battula, Venkata L., Mak, Po Yee, Schallmoser, Katharina, Ruvolo, Peter, Schober, Wendy D., Shpall, Elizabeth J., Nguyen, Martin H., Strunk, Dirk, Bueso-Ramos, Carlos E., Konoplev, Sergej, Davis, R. Eric, Konopleva, Marina, Andreeff, Michael
Published in Blood (24.04.2014)
Published in Blood (24.04.2014)
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Peroxisome proliferator-activated receptor γ and retinoid X receptor ligands are potent inducers of differentiation and apoptosis in leukemias
Konopleva, Marina, Elstner, Elena, McQueen, Teresa J, Tsao, Twee, Sudarikov, Andrey, Hu, Wei, Schober, Wendy D, Wang, Rui-Yu, Chism, David, Kornblau, Steven M, Younes, Anas, Collins, Steven J, Koeffler, H Phillip, Andreeff, Michael
Published in Molecular cancer therapeutics (01.10.2004)
Published in Molecular cancer therapeutics (01.10.2004)
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Regulation and Targeting of Eg5, a Mitotic Motor Protein in Blast Crisis CML: Overcoming Imatinib Resistance
Carter, Bing Z., Mak, Duncan H., Shi, Yuexi, Schober, Wendy D, Wang, Rui-Yu, Konopleva, Marina, Koller, Erich, Dean, Nicholas M., Andreeff, Michael
Published in Cell cycle (Georgetown, Tex.) (01.10.2006)
Published in Cell cycle (Georgetown, Tex.) (01.10.2006)
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Evaluation of apoptosis induction by concomitant inhibition of MEK, mTOR, and Bcl-2 in human acute myelogenous leukemia cells
Zhang, Weiguo, Ruvolo, Vivian R, Gao, Chen, Zhou, Liran, Bornmann, William, Tsao, Twee, Schober, Wendy D, Smith, Paul, Guichard, Sylvie, Konopleva, Marina, Andreeff, Michael
Published in Molecular cancer therapeutics (01.07.2014)
Published in Molecular cancer therapeutics (01.07.2014)
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Blockade of Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase and Murine Double Minute Synergistically Induces Apoptosis in Acute Myeloid Leukemia via BH3-Only Proteins Puma and Bim
WEIGUO ZHANG, KONOPLEVA, Marina, BURKS, Jared K, DYWER, Karen C, SCHOBER, Wendy D, YANG, Jer-Yen, MCQUEEN, Teresa J, HUNG, Mien-Chie, ANDREEFF, Michael
Published in Cancer research (Chicago, Ill.) (15.03.2010)
Published in Cancer research (Chicago, Ill.) (15.03.2010)
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Regulation of survivin expression through Bcr-Abl/MAPK cascade: targeting survivin overcomes imatinib resistance and increases imatinib sensitivity in imatinib-responsive CML cells
Carter, Bing Z., Mak, Duncan H., Schober, Wendy D., Cabreira-Hansen, Maria, Beran, Miloslav, McQueen, Teresa, Chen, Wenjing, Andreeff, Michael
Published in Blood (15.02.2006)
Published in Blood (15.02.2006)
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Caspase-independent cell death in AML: caspase inhibition in vitro with pan-caspase inhibitors or in vivo by XIAP or Survivin does not affect cell survival or prognosis
Carter, Bing Z., Kornblau, Steven M., Tsao, Twee, Wang, Rui-Yu, Schober, Wendy D., Milella, Michele, Sung, Hsi-Guang, Reed, John C., Andreeff, Michael
Published in Blood (01.12.2003)
Published in Blood (01.12.2003)
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Synergistic induction of apoptosis by simultaneous disruption of the Bcl-2 and MEK/MAPK pathways in acute myelogenous leukemia
Milella, Michele, Estrov, Zeev, Kornblau, Steven M., Carter, Bing Z., Konopleva, Marina, Tari, Ana, Schober, Wendy D., Harris, David, Leysath, Clinton E., Lopez-Berestein, Gabriel, Huang, Ziwei, Andreeff, Michael
Published in Blood (01.05.2002)
Published in Blood (01.05.2002)
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Tetra-O-methyl nordihydroguaiaretic acid inhibits growth and induces death of leukemia cells independent of Cdc2 and survivin
Mak, Duncan H., Schober, Wendy D., Chen, Wenjing, Heller, Jonathan, Andreeff, Michael, Carter, Bing Z.
Published in Leukemia & lymphoma (01.01.2007)
Published in Leukemia & lymphoma (01.01.2007)
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Targeting Survivin Expression Induces Cell Proliferation Defect and SubsequentCell Death Involving Mitochondrial Pathway in Myeloid Leukemic Cells
Carter, Bing Z., Wang, Rui-Yu, Schober, Wendy D, Milella, Michele, Chism, David, Andreeff, Michael
Published in Cell cycle (Georgetown, Tex.) (12.09.2003)
Published in Cell cycle (Georgetown, Tex.) (12.09.2003)
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GCS-100 Induces Apoptosis of Acute Myeloid Leukemia Cells By Disrupting Galectin-Mediated Survival Signaling
Davis, Richard E., Ruvolo, Vivian R, Wang, Zhiqiang, Ma, Wencai, Schober, Wendy D., Rolke, James, Tidmarsh, George, Andreeff, Michael, Ruvolo, Peter P.
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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